This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
HSP60
catalog :
15282-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 26
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 2a
Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, et al. Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice. Int J Biol Sci. 2020;16:284-297 pubmed publisher
Jiang D, Cui H, Xie N, Banerjee S, Liu R, Dai H, et al. ATF4 Mediates Mitochondrial Unfolded Protein Response (UPRmt) in Alveolar Epithelial Cells. Am J Respir Cell Mol Biol. 2020;: pubmed publisher
Zhou H, Yuan D, Gao W, Tian J, Sun H, Yu S, et al. Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia. IUBMB Life. 2020;72:1659-1679 pubmed publisher
Meng F, Wu L, Dong L, Mitchell A, James Block C, Liu J, et al. EGFL9 promotes breast cancer metastasis by inducing cMET activation and metabolic reprogramming. Nat Commun. 2019;10:5033 pubmed publisher
Santiago J, Silva J, Fardilha M. First Insights on the Presence of the Unfolded Protein Response in Human Spermatozoa. Int J Mol Sci. 2019;20: pubmed publisher
Yang X, Zhao H, Wang Y, Liu J, Guo M, Fei D, et al. The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum. Biol Trace Elem Res. 2019;: pubmed publisher
Wang W, Wang M, Ruan Y, Tan J, Wang H, Yang T, et al. Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy. J Agric Food Chem. 2019;: pubmed publisher
Kato R, Ijiri Y, Hayashi T, Uetrecht J. The 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes; Implications for Carbamazepine-induced Hypersensitivity Reactions. Drug Metab Dispos. 2019;: pubmed publisher
Zhang Z, Wang N, Ma Q, Chen Y, Yao L, Zhang L, et al. Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells. Acta Pharmacol Sin. 2019;: pubmed publisher
Xu H, Li Y, Liu R, Wu L, Zhang C, Ding N, et al. Protective effects of ghrelin on brain mitochondria after cardiac arrest and resuscitation. Neuropeptides. 2019;: pubmed publisher
Guan M, Zhang Y, Huang Q, He L, Fang Q, Zhang J, et al. Fetal bovine serum inhibits neomycin-induced apoptosis of hair cell-like HEI-OC-1 cells by maintaining mitochondrial function. Am J Transl Res. 2019;11:1343-1358 pubmed
Li B, Cao Y, Meng G, Qian L, Xu T, Yan C, et al. Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway. EBioMedicine. 2019;39:239-254 pubmed publisher
Ryan T, Yamaguchi D, Schmidt C, Zeczycki T, Shaikh S, Brophy P, et al. Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants. JCI Insight. 2018;3: pubmed publisher
Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, et al. Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis. Cancer Sci. 2018;109:3762-3773 pubmed publisher
Liu J, Zhao H, Wang Y, Shao Y, Zhang L, Xing M. Impacts of simultaneous exposure to arsenic (III) and copper (II) on inflammatory response, immune homeostasis, and heat shock response in chicken thymus. Int Immunopharmacol. 2018;64:60-68 pubmed publisher
Flippo K, Gnanasekaran A, Perkins G, Ajmal A, Merrill R, Dickey A, et al. AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission. J Neurosci. 2018;38:8233-8242 pubmed publisher
Xu B, Lian S, Li S, Guo J, Wang J, Wang D, et al. GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose. Brain Res Bull. 2018;142:163-175 pubmed publisher
González Serrano L, Karim L, Pierre F, Schwenzer H, Rotig A, Munnich A, et al. Three human aminoacyl-tRNA synthetases have distinct sub-mitochondrial localizations that are unaffected by disease-associated mutations. J Biol Chem. 2018;293:13604-13615 pubmed publisher
Wang Y, Zhao H, Liu J, Shao Y, Li J, Luo L, et al. Copper and arsenic-induced oxidative stress and immune imbalance are associated with activation of heat shock proteins in chicken intestines. Int Immunopharmacol. 2018;60:64-75 pubmed publisher
Shao Y, Zhao H, Wang Y, Liu J, Li J, Chai H, et al. Arsenic and/or copper caused inflammatory response via activation of inducible nitric oxide synthase pathway and triggered heat shock protein responses in testis tissues of chicken. Environ Sci Pollut Res Int. 2018;25:7719-7729 pubmed publisher
Chang C, Liu W, Hung H, Gean C, Tsai H, Su C, et al. Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells. BMC Cancer. 2017;17:905 pubmed publisher
Wang Y, Zhao H, Shao Y, Liu J, Li J, Xing M. Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken. Oncotarget. 2017;8:98103-98116 pubmed publisher
Wu L, Guo X, Lyu Y, Clarke S, Lucas E, Smith B, et al. Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice. Sci Rep. 2017;7:14624 pubmed publisher
Liu X, Wang W, Song G, Wei X, Zeng Y, Han P, et al. Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network. PLoS ONE. 2017;12:e0182558 pubmed publisher
Shi M, Liu Y, Feng L, Cui Y, Chen Y, Wang P, et al. Protective Effects of Scutellarin on Human Cardiac Microvascular Endothelial Cells against Hypoxia-Reoxygenation Injury and Its Possible Target-Related Proteins. Evid Based Complement Alternat Med. 2015;2015:278014 pubmed publisher
Zhao Y, Zhang C, Wei X, Li P, Cui Y, Qin Y, et al. Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation. Sci Rep. 2015;5:15352 pubmed publisher
product information
CatalogNo :
15282-1-AP
AntigenName :
HSP60
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
heat shock 60kDa protein 1 (chaperonin)
Immunogen :
Recombinant Protein
Species :
chick, chicken, human, mouse, rat, rice
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
60 kDa chaperonin, Chaperonin 60, CPN60, GROEL, Heat shock protein 60, HLD4, HSP 60, HSP60, HSP65, HSPD1, HuCHA60, P60 lymphocyte protein, SPG13
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC003030
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:50 ; IHC 1:100 ; IP 1:4000 ; WB 1:30000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.