This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
OGDH
catalog :
15212-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, western blot knockout validation
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; loading ...; fig s6e
Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 11a
  • immunocytochemistry; human; loading ...; fig 1c, 2c
Dobolyi A, Bagó A, Palkovits M, Nemeria N, Jordan F, Doczi J, et al. Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation. Brain Struct Funct. 2020;225:639-667 pubmed publisher
Babetto E, Wong K, Beirowski B. A glycolytic shift in Schwann cells supports injured axons. Nat Neurosci. 2020;: pubmed publisher
Feng Q, Li X, Sun W, Sun M, Li Z, Sheng H, et al. Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1. Biochem Pharmacol. 2020;178:114092 pubmed publisher
Baksh S, Todorova P, Gur Cohen S, Hurwitz B, Ge Y, Novak J, et al. Extracellular serine controls epidermal stem cell fate and tumour initiation. Nat Cell Biol. 2020;22:779-790 pubmed publisher
Miura Y, Hayakawa A, Kikuchi S, Tsumoto H, Umezawa K, Chiba Y, et al. Fumarate accumulation involved in renal diabetic fibrosis in Goto-Kakizaki rats. Arch Biochem Biophys. 2019;678:108167 pubmed publisher
Wang T, Yao J, Chen S, Mao Z, Brinton R. Allopregnanolone Reverses Bioenergetic Deficits in Female Triple Transgenic Alzheimer's Mouse Model. Neurotherapeutics. 2019;: pubmed publisher
Tang K, Yu Y, Zhu L, Xu P, Chen J, Ma J, et al. Hypoxia-reprogrammed tricarboxylic acid cycle promotes the growth of human breast tumorigenic cells. Oncogene. 2019;: pubmed publisher
Graham L, Naldrett M, Kohama S, Smith C, Lamont D, McColl B, et al. Regional Molecular Mapping of Primate Synapses during Normal Healthy Aging. Cell Rep. 2019;27:1018-1026.e4 pubmed publisher
Hamanaka R, O Leary E, Witt L, Tian Y, Gökalp G, Meliton A, et al. Glutamine Metabolism is Required for Collagen Protein Synthesis in Lung Fibroblasts. Am J Respir Cell Mol Biol. 2019;: pubmed publisher
Jin W, Jin W, Pan D. Ifi27 is indispensable for mitochondrial function and browning in adipocytes. Biochem Biophys Res Commun. 2018;501:273-279 pubmed publisher
Hu Z, Du M, Lai W, Liang Y, Liu Q, Mo Y, et al. Energy Metabolism in the Bone is Associated with Histomorphometric Changes in Rats with Hyperthyroidism. Cell Physiol Biochem. 2018;46:1471-1482 pubmed publisher
Chen Q, Kirk K, Shurubor Y, Zhao D, Arreguin A, Shahi I, et al. Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations. Cell Metab. 2018;27:1007-1025.e5 pubmed publisher
Wu L, Cao K, Ni Z, Li W, Chen Z, Cheng H, et al. Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice. J Ethnopharmacol. 2018;222:71-78 pubmed publisher
Gu Z, Zhang H, Li Y, Shen S, Yin X, Zhang W, et al. CDC5L drives FAH expression to promote metabolic reprogramming in melanoma. Oncotarget. 2017;8:114328-114343 pubmed publisher
Graham L, Eaton S, Brunton P, Atrih A, Smith C, Lamont D, et al. Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture. Mol Neurodegener. 2017;12:77 pubmed publisher
Schatton D, Pla Martín D, Marx M, Hansen H, Mourier A, Nemazanyy I, et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017;216:675-693 pubmed publisher
Han C, Yang L, Choi H, Baddour J, Achreja A, Liu Y, et al. Amplification of USP13 drives ovarian cancer metabolism. Nat Commun. 2016;7:13525 pubmed publisher
Allen E, Ulanet D, Pirman D, Mahoney C, Coco J, Si Y, et al. Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDH. Cell Rep. 2016;17:876-890 pubmed publisher
product information
CatalogNo :
15212-1-AP
AntigenName :
OGDH
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat, sheep
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
AKGDH, E1k, OGDC, OGDC E1, OGDH
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC004964
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Organelle Marker;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; WB 1:8000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.