This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CHOP; GADD153
catalog :
15204-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 129
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2e
Yang X, Guo Q, Feng T, Lu Q, Ge L, Pan J, et al. IL13Rα1 protects against rheumatoid arthritis by combating the apoptotic resistance of fibroblast-like synoviocytes. Arthritis Res Ther. 2020;22:184 pubmed publisher
  • western blot; mouse; loading ...; fig s3b
Zhang S, Liu W, Yang Y, Sun K, Li S, Xu H, et al. Tmem30a Deficiency in endothelial cells impairs cell proliferation and angiogenesis. J Cell Sci. 2019;: pubmed publisher
  • western blot; mouse; 1:400; loading ...; fig 3c
Lei X, Cui K, Liu Q, Zhang H, Li Z, Huang B, et al. Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway. Reprod Domest Anim. 2016;51:75-84 pubmed publisher
Li B, Yao J, Guo K, He F, Chen K, Lin Z, et al. Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators. Eur J Med Chem. 2020;204:112608 pubmed publisher
Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, et al. Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1. J Cell Mol Med. 2020;: pubmed publisher
Chen K, Chen Y, Cheng C, Jhan K, Wang L. Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes. Parasit Vectors. 2020;13:317 pubmed publisher
Wang Y, Li C, Li J, Wang G, Li L. Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, et al. Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway. Brain Res Bull. 2020;162:73-83 pubmed publisher
Pang X, Qiao Q, Vonglorkham S, Feng Z, Pang L, Chen S, et al. Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy. Biomed Pharmacother. 2020;129:110375 pubmed publisher
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu B, et al. Role of Endoplasmic Reticulum Stress in Otitis Media. Front Genet. 2020;11:495 pubmed publisher
Tang X, Yu Q, Wen X, Qi D, Peng J, He J, et al. Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue. Shock. 2020;54:110-118 pubmed publisher
Yuan F, Jiang H, Yin H, Jiang X, Jiao F, Chen S, et al. Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation. Nat Commun. 2020;11:2847 pubmed publisher
Dong Q, Chen Y, Liu W, Liu X, Chen A, Yang X, et al. 25-Hydroxycholesterol promotes vascular calcification via activation of endoplasmic reticulum stress. Eur J Pharmacol. 2020;880:173165 pubmed publisher
Xiong Y, Jin E, Yin Q, Che C, He S. Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells. Biol Trace Elem Res. 2020;: pubmed publisher
Zhou H, Yuan D, Gao W, Tian J, Sun H, Yu S, et al. Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia. IUBMB Life. 2020;72:1659-1679 pubmed publisher
Song L, Piao Z, Yao L, Zhang L, Lu Y. Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats. Exp Anim. 2020;69:363-373 pubmed publisher
Xiong Y, Xin D, Hu Q, Wang L, Qiu J, Yuan H, et al. Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage. Neural Regen Res. 2020;15:1920-1930 pubmed publisher
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, et al. Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biol. 2020;32:101514 pubmed publisher
Sümegi A, Hendrik Z, Gáll T, Felszeghy E, Szakszon K, Antal Szalmas P, et al. A novel splice site indel alteration in the EIF2AK3 gene is responsible for the first cases of Wolcott-Rallison syndrome in Hungary. BMC Med Genet. 2020;21:61 pubmed publisher
Tang L, Ren X, Han Y, Chen L, Meng X, Zhang C, et al. Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum. Neurochem Int. 2020;136:104728 pubmed publisher
Zhang X, Wang Y, Tong J, Ning X, Zhou F, Yang X, et al. Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells. FEBS Open Bio. 2020;10:827-834 pubmed publisher
Xiong Y, Yin Q, Li J, He S. Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes. Animals (Basel). 2020;10: pubmed publisher
Dong Y, Xing Y, Sun J, Sun W, Xu Y, Quan C. Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway. Molecules. 2020;25: pubmed publisher
Xiong Y, Yin Q, Jin E, Chen H, He S. Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells. Molecules. 2020;25: pubmed publisher
Zhang L, Zhou Y, Xia Q, Chen Y, Li J. All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells. Toxicol Lett. 2020;322:77-86 pubmed publisher
Chen K, Hua H, Zhu Z, Wu T, Jia Z, Liu Q. Artemisinin and dihydroartemisinin promote β-cell apoptosis induced by palmitate via enhancing ER stress. Apoptosis. 2020;: pubmed publisher
Xu W, Tao M, Hu Z, Chang T, Wang Y. Minocycline induces apoptosis of photoreceptor cells by regulating ER stress. Exp Eye Res. 2020;190:107887 pubmed publisher
Zhang W, Zhu T, Chen L, Luo W, Chao J. MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR. Am J Physiol Heart Circ Physiol. 2020;318:H59-H71 pubmed publisher
Zheng D, Chen Y, Ai S, Zhang R, Gao Z, Liang C, et al. Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress. Research (Wash D C). 2019;2019:4803624 pubmed publisher
Zhong X, Wang B, Zhang G, Yuan Y, Hu X, Xiong J, et al. Autophagy Activation Is Involved in Acidic Fibroblast Growth Factor Ameliorating Parkinson's Disease via Regulating Tribbles Homologue 3. Front Pharmacol. 2019;10:1428 pubmed publisher
Harvey R, Pöyry T, Stoneley M, Willis A. Signaling from mTOR to eIF2α mediates cell migration in response to the chemotherapeutic doxorubicin. Sci Signal. 2019;12: pubmed publisher
Sun Y, Gong J, Cao Y. Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?. Int J Nanomedicine. 2019;14:9285-9294 pubmed publisher
Zhu H, Liu L, Deng H, Li Z, Sheng J, He X, et al. Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma. J Cell Physiol. 2019;: pubmed publisher
Tang Q, Ren L, Liu J, Li W, Zheng X, Wang J, et al. Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis. Cell Prolif. 2019;:e12706 pubmed publisher
Doycheva D, Xu N, Kaur H, Malaguit J, McBride D, Tang J, et al. Adenoviral TMBIM6 vector attenuates ER-stress-induced apoptosis in a neonatal hypoxic-ischemic rat model. Dis Model Mech. 2019;12: pubmed publisher
Hu J, Wu Q, Wang Z, Hong J, Chen R, Li B, et al. Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress. Biomed Pharmacother. 2019;120:109475 pubmed publisher
Xin X, Zhang R, Yuan X, Liu L. Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line. Med Sci Monit. 2019;25:7100-7114 pubmed publisher
Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, et al. Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway. Oxid Med Cell Longev. 2019;2019:8781690 pubmed publisher
Li S, Jiang W, Xiao W, Li K, Zhang Y, Guo X, et al. KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma. World J Gastrointest Oncol. 2019;11:599-621 pubmed publisher
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, et al. Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1. EMBO Rep. 2019;:e48115 pubmed publisher
Li C, Pan Y, Gao Y, Shi F, Wang Y, Sun X. Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity. Apoptosis. 2019;24:812-825 pubmed publisher
Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, et al. Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo. Theranostics. 2019;9:4084-4100 pubmed publisher
Yu M, Qin H, Wang H, Liu J, Liu S, Yan Q. N-glycosylation of uterine endometrium determines its receptivity. J Cell Physiol. 2019;: pubmed publisher
Chen X, Bian M, Jin H, Lian N, Shao J, Zhang F, et al. Dihydroartemisinin attenuates alcoholic fatty liver through regulation of lipin-1 signaling. IUBMB Life. 2019;: pubmed publisher
Wang Q, Xin X, Wang T, Wan J, Ou Y, Yang Z, et al. Japanese encephalitis virus induces apoptosis and encephalitis by activating the PERK pathway. J Virol. 2019;: pubmed publisher
Ye J, Qi L, Chen K, Li R, Song S, Zhou C, et al. Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo. Int J Oncol. 2019;55:331-339 pubmed publisher
Xie Y, Zhou X, Yuan H, Qiu J, Xin D, Chu X, et al. Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress. Neural Regen Res. 2019;14:1734-1742 pubmed publisher
Huang W, Liang Y, Ma X. Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells. Cancer Cell Int. 2019;19:151 pubmed publisher
Xu W, Wu Y, Hu Z, Sun L, Dou G, Zhang Z, et al. Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity. Mol Ther Nucleic Acids. 2019;16:778-790 pubmed publisher
Tang S, Wang J, Liu J, Huang Y, Zhou Y, Yang S, et al. Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway. Ren Fail. 2019;41:455-466 pubmed publisher
Stein M, Malhotra J, Tarapore R, Malhotra U, Silk A, Chan N, et al. Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration. J Immunother Cancer. 2019;7:136 pubmed publisher
Zhang L, Xia Q, Zhou Y, Li J. Endoplasmic reticulum stress and autophagy contribute to cadmium-induced cytotoxicity in retinal pigment epithelial cells. Toxicol Lett. 2019;311:105-113 pubmed publisher
Yang H, Li J, Yang C, Liu H, Cao Y. Multi-walled carbon nanotubes promoted lipid accumulation in human aortic smooth muscle cells. Toxicol Appl Pharmacol. 2019;374:11-19 pubmed publisher
Long J, Ma W, Yu Z, Liu H, Cao Y. Multi-walled carbon nanotubes (MWCNTs) promoted lipid accumulation in THP-1 macrophages through modulation of endoplasmic reticulum (ER) stress. Nanotoxicology. 2019;:1-14 pubmed publisher
Zhao Y, Yan J, Li A, Zhang Z, Li Z, Guo K, et al. Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats. Toxicol Lett. 2019;310:31-38 pubmed publisher
Lindén M, Thomsen C, Grundevik P, Jonasson E, Andersson D, Runnberg R, et al. FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex. EMBO Rep. 2019;20: pubmed publisher
Yin M, Shen Z, Yang L, Zheng W, Song H. Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway. Int J Mol Med. 2019;43:2086-2102 pubmed publisher
Ji Y, Ge Y, Xu X, Ye S, Fan Y, Zhang J, et al. Vildagliptin Reduces Stenosis of Injured Carotid Artery in Diabetic Mouse Through Inhibiting Vascular Smooth Muscle Cell Proliferation via ER Stress/NF-κB Pathway. Front Pharmacol. 2019;10:142 pubmed publisher
Zhao Y, Yu Y, Li H, Zhang Z, Guo S, Zhu S, et al. FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma. Mol Oncol. 2019;13:1150-1165 pubmed publisher
Moss S, Taylor I, Ruggero D, Gestwicki J, Shokat K, Mukherjee S. A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis. Cell Host Microbe. 2019;25:454-462.e6 pubmed publisher
Huang C, Yao R, Zhu Z, Pang D, Cao X, Feng B, et al. A pectic polysaccharide from water decoction of Xinjiang Lycium barbarum fruit protects against intestinal endoplasmic reticulum stress. Int J Biol Macromol. 2019;130:508-514 pubmed publisher
Fu Z, Liu F, Liu C, Jin B, Jiang Y, Tang M, et al. Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability. Biochim Biophys Acta Mol Basis Dis. 2019;1865:1428-1435 pubmed publisher
Xu S, Di Z, He Y, Wang R, Ma Y, Sun R, et al. Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress. J Neuroinflammation. 2019;16:35 pubmed publisher
Sun X, Zhao D, Lu F, Peng S, Yu M, Liu N, et al. Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys44 to prevent cardiac structural damage in diabetic cardiomyopathy. Br J Pharmacol. 2019;: pubmed publisher
Wu W, Li W, Wei J, Wang C, Yao Y, Zhu W, et al. Chronic intermittent hypoxia accelerates liver fibrosis in rats with combined hypoxia and nonalcoholic steatohepatitis via angiogenesis rather than endoplasmic reticulum stress. Acta Biochim Biophys Sin (Shanghai). 2019;51:159-167 pubmed publisher
Gu M, Zhao P, Zhang S, Fan S, Yang L, Tong Q, et al. Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice. Br J Pharmacol. 2019;176:847-863 pubmed publisher
Ullah O, Li Z, Ali I, Xu L, Liu H, Jin H, et al. Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos. In Vitro Cell Dev Biol Anim. 2019;55:82-93 pubmed publisher
Hong J, Hu Z, Wu Q, Tang C, Hu J, Chen R, et al. The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration. Biosci Rep. 2019;39: pubmed publisher
Nie J, Duan Q, He M, Li X, Wang B, Zhou C, et al. Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na+ and Ca2+ handling. J Cell Physiol. 2019;234:11587-11601 pubmed publisher
Wu Y, Yue Y, Fu S, Li Y, Wu D, Lv J, et al. Icariside II prevents hypertensive heart disease by alleviating endoplasmic reticulum stress via the PERK/ATF-4/CHOP signalling pathway in spontaneously hypertensive rats. J Pharm Pharmacol. 2019;71:400-407 pubmed publisher
Li S, Jiang Z, Chai W, Xu Y, Wang Y. Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons. Neurochem Int. 2019;122:73-84 pubmed publisher
Azhary J, Harada M, Takahashi N, Nose E, Kunitomi C, Koike H, et al. Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS. Endocrinology. 2019;160:119-132 pubmed publisher
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells. Inflammation. 2019;42:64-80 pubmed publisher
Wang X, Xia H, Qin H, Kang X, Hu H, Zheng J, et al. 20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway. J Cell Biochem. 2019;120:5085-5096 pubmed publisher
Wang M, Yang Q, Long J, Ding Y, Zou X, Liao G, et al. A comparative study of toxicity of TiO2, ZnO, and Ag nanoparticles to human aortic smooth-muscle cells. Int J Nanomedicine. 2018;13:8037-8049 pubmed publisher
Yamaguchi Y, Oh hashi K, Matsuoka Y, Takemura H, Yamakita S, Matsuda M, et al. Endoplasmic Reticulum Stress in the Dorsal Root Ganglion Contributes to the Development of Pain Hypersensitivity after Nerve Injury. Neuroscience. 2018;394:288-299 pubmed publisher
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, et al. Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism. Int Immunopharmacol. 2018;65:256-267 pubmed publisher
Pang X, Zhang Y, Shi X, Li D, Han J. ERp44 depletion exacerbates ER stress and aggravates diabetic nephropathy in db/db mice. Biochem Biophys Res Commun. 2018;504:921-926 pubmed publisher
Chen T, Zhu H, Wang Y, Zhao P, Chen J, Sun J, et al. Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways. Am J Transl Res. 2018;10:2555-2566 pubmed
Xu Y, Sun D, Song C, Wang R, Dong X. MnTMPyP inhibits paraquat-induced pulmonary epithelial-like cell injury by inhibiting oxidative stress. J Toxicol Sci. 2018;43:545-555 pubmed publisher
Duan Y, Jin Y, Guo M, Duan L, Wang J. Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture. J Cancer. 2018;9:2723-2733 pubmed publisher
Chen J, Zhang Z, Song J, Liu Q, Wang C, Huang Z, et al. 18?-Glycyrrhetinic-acid-mediated unfolded protein response induces autophagy and apoptosis in hepatocellular carcinoma. Sci Rep. 2018;8:9365 pubmed publisher
Geng W, Qin F, Ren J, Xiao S, Wang A. Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice. Exp Cell Res. 2018;369:243-250 pubmed publisher
Cai Y, Zheng Y, Gu J, Wang S, Wang N, Yang B, et al. Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78. Cell Death Dis. 2018;9:636 pubmed publisher
Wang X, Han X, Li M, Han Y, Zhang Y, Zhao S, et al. Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress. Microvasc Res. 2018;119:98-104 pubmed publisher
Li Z, Meng Z, Lu J, Chen F, Wong W, Tse G, et al. TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2018;120:1-11 pubmed publisher
Liu L, Xu L, Zhang S, Wang D, Dong G, Chen H, et al. STF-083010, an inhibitor of XBP1 splicing, attenuates acute renal failure in rats by suppressing endoplasmic reticulum stress-induced apoptosis and inflammation. Exp Anim. 2018;67:373-382 pubmed publisher
Tan N, Li X, Zhai L, Liu D, Li J, Yokota H, et al. Effects of knee loading on obesity-related non-alcoholic fatty liver disease in an ovariectomized mouse model with high-fat diet. Hepatol Res. 2018;48:839-849 pubmed publisher
Wang Z, Cui R, Wang K. Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78. Exp Ther Med. 2018;15:2818-2823 pubmed publisher
Tsai T, Lai K, Su J, Wu Y, Sheu J. 7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway. Mar Drugs. 2018;16: pubmed publisher
Chan J, Bittner S, Bittner A, Atwal S, Shen W, Inayathullah M, et al. Nordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet-Induced Metabolic Dysfunction in Mice. J Pharmacol Exp Ther. 2018;365:281-290 pubmed publisher
Sun Z, Zhang H, Wang X, Wang Q, Zhang C, Wang J, et al. TMCO1 is essential for ovarian follicle development by regulating ER Ca2+ store of granulosa cells. Cell Death Differ. 2018;25:1686-1701 pubmed publisher
Zhao J, Xiang X, Zhang H, Jiang D, Liang Y, Qing W, et al. CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage. Exp Neurol. 2018;302:22-33 pubmed publisher
Chen X, Bian M, Zhang C, Kai J, Yao Z, Jin H, et al. Dihydroartemisinin inhibits ER stress-mediated mitochondrial pathway to attenuate hepatocyte lipoapoptosis via blocking the activation of the PI3K/Akt pathway. Biomed Pharmacother. 2018;97:975-984 pubmed publisher
Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, et al. Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes. Cell Biosci. 2017;7:67 pubmed publisher
Zong S, Liu T, Wan F, Chen P, Luo P, Xiao H. Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model. Audiol Neurootol. 2017;22:160-168 pubmed publisher
Liu M, Liu S, Tan W, Tang F, Long J, Li Z, et al. Gaseous signalling molecule SO2 via Hippo?MST pathway to improve myocardial fibrosis of diabetic rats. Mol Med Rep. 2017;16:8953-8963 pubmed publisher
Liu X, Jin X, Su R, Li Z. The reproductive toxicology of male SD rats after PM2.5 exposure mediated by the stimulation of endoplasmic reticulum stress. Chemosphere. 2017;189:547-555 pubmed publisher
Shao J, Yin Y, Yin X, Ji L, Xin Y, Zou J, et al. Transthyretin Exerts Pro-Apoptotic Effects in Human Retinal Microvascular Endothelial Cells Through a GRP78-Dependent Pathway in Diabetic Retinopathy. Cell Physiol Biochem. 2017;43:788-800 pubmed publisher
Huang R, Zhang Y, Han B, Bai Y, Zhou R, Gan G, et al. Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG. Autophagy. 2017;13:1722-1741 pubmed publisher
Liu S, Xin D, Wang L, Zhang T, Bai X, Li T, et al. Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress. Redox Biol. 2017;13:528-540 pubmed publisher
Huang Y, Zhu D, Chen X, Chen Q, Luo Z, Liu C, et al. Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway. Oncotarget. 2017;8:40264-40275 pubmed publisher
Zhou B, Zhou D, Wei X, Zhong R, Xu J, Sun L. Astragaloside IV attenuates free fatty acid-induced ER stress and lipid accumulation in hepatocytes via AMPK activation. Acta Pharmacol Sin. 2017;38:998-1008 pubmed publisher
Cai Q, Zhao M, Liu X, Wang X, Nie Y, Li P, et al. Reduced expression of citrate synthase leads to excessive superoxide formation and cell apoptosis. Biochem Biophys Res Commun. 2017;485:388-394 pubmed publisher
Colvin B, Longtine M, Chen B, Costa M, Nelson D. Oleate attenuates palmitate-induced endoplasmic reticulum stress and apoptosis in placental trophoblasts. Reproduction. 2017;153:369-380 pubmed publisher
Jiang Y, Chen X, Fan M, Li H, Zhu W, Chen X, et al. TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-?B pathway. Mol Immunol. 2017;82:123-136 pubmed publisher
Yang F, Yu X, Li T, Wu J, Zhao Y, Liu J, et al. Exogenous H2S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes. Am J Physiol Endocrinol Metab. 2017;312:E190-E203 pubmed publisher
Dai C, Lei L, Li B, Lin Y, Xiao X, Tang S. Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin. Toxicol Mech Methods. 2017;27:165-172 pubmed publisher
Li J, Yang S, Li X, Liu D, Wang Z, Guo J, et al. Role of endoplasmic reticulum stress in disuse osteoporosis. Bone. 2017;97:2-14 pubmed publisher
Wu H, Wang Y, Wu C, Yang P, Li H, Li Z. Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission. J Agric Food Chem. 2016;64:9356-9367 pubmed
Iizuka Y, Kim H, Izawa T, Sakurai K, Hirako S, Wada M, et al. Protective effects of fish oil and pioglitazone on pancreatic tissue in obese KK mice with type 2 diabetes. Prostaglandins Leukot Essent Fatty Acids. 2016;115:53-59 pubmed publisher
Liu J, Li M, Gong J, Han P, Wang Y, Li D, et al. Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells. Biol Open. 2017;6:29-34 pubmed publisher
Sidoli M, Musner N, Silvestri N, Ungaro D, D Antonio M, Cavener D, et al. Ablation of Perk in Schwann Cells Improves Myelination in the S63del Charcot-Marie-Tooth 1B Mouse. J Neurosci. 2016;36:11350-11361 pubmed
Li T, Feng R, Zhao C, Wang Y, Wang J, Liu S, et al. Dimethylarginine Dimethylaminohydrolase 1 Protects Against High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice. Antioxid Redox Signal. 2017;26:598-609 pubmed publisher
Chen Y, Liu Y, Lin S, Yang S, Que H, Liu S. Identification of Novel SCIRR69-Interacting Proteins During ER Stress Using SILAC-Immunoprecipitation Quantitative Proteomics Approach. Neuromolecular Med. 2017;19:81-93 pubmed publisher
Wang Q, Duan L, Xu Z, Wang J, Xi S. The protective effect of the earthworm active ingredients on hepatocellular injury induced by endoplasmic reticulum stress. Biomed Pharmacother. 2016;82:304-11 pubmed publisher
Zhang W, Chen L, Shen Y, Xu J. Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway. Toxicol In Vitro. 2016;36:186-196 pubmed publisher
Bai X, Liu S, Yuan L, Xie Y, Li T, Wang L, et al. Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice. Brain Res. 2016;1646:410-417 pubmed publisher
Wu Y, Adi D, Long M, Wang J, Liu F, Gai M, et al. 4-Phenylbutyric Acid Induces Protection against Pulmonary Arterial Hypertension in Rats. PLoS ONE. 2016;11:e0157538 pubmed publisher
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu K, et al. Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs. Biomed Pharmacother. 2016;80:63-72 pubmed publisher
Zhou Y, Zhang S, Dai C, Tang S, Yang X, Li D, et al. Quinocetone triggered ER stress-induced autophagy via ATF6/DAPK1-modulated mAtg9a trafficking. Cell Biol Toxicol. 2016;32:141-52 pubmed publisher
Huang M, Xu A, Wu X, Zhang Y, Guo Y, Guo F, et al. Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells. Arch Virol. 2016;161:699-703 pubmed publisher
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product information
CatalogNo :
15204-1-AP
AntigenName :
CHOP; GADD153
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
DNA-damage-inducible transcript 3
Immunogen :
Recombinant Protein
Species :
bovine, chicken, hamster, human, mouse, rat, swine
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
C/EBP homologous protein, C/EBP homologous protein 10, CEBPZ, CHOP, CHOP 10, CHOP10, DDIT 3, DDIT3, GADD153
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC003637
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IHC 1:50 ; WB 1:300 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.