This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SIGMAR1
catalog :
15168-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3b
Niu F, Liao K, Hu G, Sil S, Callen S, Guo M, et al. Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS. J Cell Biol. 2019;218:700-721 pubmed publisher
Liu Y, Ma X, Fujioka H, Liu J, Chen S, Zhu X. DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1. Proc Natl Acad Sci U S A. 2019;116:25322-25328 pubmed publisher
Zhai M, Liu C, Li Y, Zhang P, Yu Z, Zhu H, et al. Dexmedetomidine inhibits neuronal apoptosis by inducing Sigma-1 receptor signaling in cerebral ischemia-reperfusion injury. Aging (Albany NY). 2019;11:9556-9568 pubmed publisher
Morihara R, Yamashita T, Liu X, Nakano Y, Fukui Y, Sato K, et al. Protective effect of a novel sigma-1 receptor agonist is associated with reduced endoplasmic reticulum stress in stroke male mice. J Neurosci Res. 2018;96:1707-1716 pubmed publisher
Wang X, Wen Y, Dong J, Cao C, Yuan S. Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes. Proteomics. 2018;18:e1700478 pubmed publisher
Li D, Zhang S, Yao Y, Xiang Y, Ma X, Wei X, et al. Sigma-1 receptor agonist increases axon outgrowth of hippocampal neurons via voltage-gated calcium ions channels. CNS Neurosci Ther. 2017;23:930-939 pubmed publisher
Zhang X, Wu F, Jiao Y, Tang T, Yang L, Lu C, et al. An Increase of Sigma-1 Receptor in the Penumbra Neuron after Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2017;26:1981-1987 pubmed publisher
Zhang K, Zhao Z, Lan L, Wei X, Wang L, Liu X, et al. Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel. Front Pharmacol. 2017;8:302 pubmed publisher
Jesse C, Bushuven E, Tripathi P, Chandrasekar A, Simon C, Drepper C, et al. ALS-Associated Endoplasmic Reticulum Proteins in Denervated Skeletal Muscle: Implications for Motor Neuron Disease Pathology. Brain Pathol. 2017;27:781-794 pubmed publisher
Ka M, Kook Y, Liao K, Buch S, Kim W. Transactivation of TrkB by Sigma-1 receptor mediates cocaine-induced changes in dendritic spine density and morphology in hippocampal and cortical neurons. Cell Death Dis. 2016;7:e2414 pubmed publisher
Lim Y, Cho I, Schoel L, Cho G, Golden J. Hereditary spastic paraplegia-linked REEP1 modulates endoplasmic reticulum/mitochondria contacts. Ann Neurol. 2015;78:679-96 pubmed publisher
product information
CatalogNo :
15168-1-AP
AntigenName :
SIGMAR1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
sigma non-opioid intracellular receptor 1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, CoIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
hSigmaR1, OPRS1, SIG 1R, Sigma 1 type opioid receptor, Sigma1 receptor, Sigma1R, SIGMAR1, SR BP, SR BP1, SR31747 binding protein, SRBP
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC004899
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:200 ; WB 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.