This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
ISCU
catalog :
14812-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:6000; fig s4
  • western blot; human; 1:6000; fig s4
Nabhan J, Wood K, Rao V, Morin J, Bhamidipaty S, LaBranche T, et al. Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich's ataxia. Sci Rep. 2016;6:20019 pubmed publisher
Zhang R, Hou T, Cheng H, Wang X. NDUFAB1 protects against obesity and insulin resistance by enhancing mitochondrial metabolism. FASEB J. 2019;33:13310-13322 pubmed publisher
Niihori M, Eccles C, Kurdyukov S, Zemskova M, Varghese M, Stepanova A, et al. Rats with Human Mutation of NFU1 Develop Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2019;: pubmed publisher
Hou T, Zhang R, Jian C, Ding W, Wang Y, Ling S, et al. NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly. Cell Res. 2019;29:754-766 pubmed publisher
Ma Q, Dasgupta C, Li Y, Huang L, Zhang L. MicroRNA-210 Downregulates ISCU and Induces Mitochondrial Dysfunction and Neuronal Death in Neonatal Hypoxic-Ischemic Brain Injury. Mol Neurobiol. 2019;: pubmed publisher
Dong Y, McMillian E, Clark E, Lin H, Lynch D. GRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich Ataxia cellular models. Hum Mol Genet. 2018;: pubmed publisher
Gupta P, Singh P, Pandey H, Seth P, Mukhopadhyay C. Phosphoinositide-3-kinase inhibition elevates ferritin level resulting depletion of labile iron pool and blocking of glioma cell proliferation. Biochim Biophys Acta Gen Subj. 2018;1863:547-564 pubmed publisher
Guo W, Lian S, Zhen L, Zang S, Chen Y, Lang L, et al. The Favored Mechanism for Coping with Acute Cold Stress: Upregulation of miR-210 in Rats. Cell Physiol Biochem. 2018;46:2090-2102 pubmed publisher
Ferecatu I, Canal F, Fabbri L, Mazure N, Bouton C, Golinelli Cohen M. Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1? activation. PLoS ONE. 2018;13:e0194782 pubmed publisher
Masaldan S, Clatworthy S, Gamell C, Meggyesy P, Rigopoulos A, Haupt S, et al. Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis. Redox Biol. 2018;14:100-115 pubmed publisher
Wu L, Guo X, Lyu Y, Clarke S, Lucas E, Smith B, et al. Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice. Sci Rep. 2017;7:14624 pubmed publisher
Funauchi Y, Tanikawa C, Yi Lo P, Mori J, Daigo Y, Takano A, et al. Regulation of iron homeostasis by the p53-ISCU pathway. Sci Rep. 2015;5:16497 pubmed publisher
product information
CatalogNo :
14812-1-AP
AntigenName :
ISCU
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
iron-sulfur cluster scaffold homolog (E. coli)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
2310020H20Rik, HML, hnifU, ISCU, ISCU2, ISU2, NIFU, NifU like protein, NIFUN
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC061903
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Plasma/Serum;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:500 ; WB 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.