This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
GOT2
catalog :
14800-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; fig s20c
  • western blot; mouse; loading ...; fig 3c
Wang P, Xu J, Wang Y, Cao X. An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism. Science. 2017;358:1051-1055 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Li W, Chen C, Zhao X, Ye H, Zhao Y, Fu Z, et al. HIF-2? regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma. J Cell Mol Med. 2017;21:2896-2908 pubmed publisher
Xu J, Khoury N, Jackson C, Escobar I, Stegelmann S, Dave K, et al. Ischemic Neuroprotectant PKCε Restores Mitochondrial Glutamate Oxaloacetate Transaminase in the Neuronal NADH Shuttle after Ischemic Injury. Transl Stroke Res. 2019;: pubmed publisher
Hamanaka R, O Leary E, Witt L, Tian Y, Gökalp G, Meliton A, et al. Glutamine Metabolism is Required for Collagen Protein Synthesis in Lung Fibroblasts. Am J Respir Cell Mol Biol. 2019;: pubmed publisher
Hong R, Zhang W, Xia X, Zhang K, Wang Y, Wu M, et al. Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation. Mol Oncol. 2019;13:959-977 pubmed publisher
Cai W, Zhang C, Wu Y, Zhuang G, Ye Z, Zhang C, et al. Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion. Cell Res. 2018;: pubmed publisher
Feist M, Schwarzfischer P, Heinrich P, Sun X, Kemper J, von Bonin F, et al. Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression. Nat Commun. 2018;9:1514 pubmed publisher
Chen Q, Kirk K, Shurubor Y, Zhao D, Arreguin A, Shahi I, et al. Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations. Cell Metab. 2018;27:1007-1025.e5 pubmed publisher
Wang Y, Wang H, Xu J, Tan J, Fu L, Wang J, et al. Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner. Nat Commun. 2018;9:545 pubmed publisher
Tan H, Sim A, Long Y. Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation. Nat Commun. 2017;8:338 pubmed publisher
Kitazawa S, Ebara S, Ando A, Baba Y, Satomi Y, Soga T, et al. Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors. Oncotarget. 2017;8:28922-28938 pubmed publisher
Qin S, Zhou Y, Gray L, Kusebauch U, McEvoy L, Antoine D, et al. Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients. J Proteome Res. 2016;15:3724-3740 pubmed
Sun L, Song L, Wan Q, Wu G, Li X, Wang Y, et al. cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions. Cell Res. 2015;25:429-44 pubmed publisher
product information
CatalogNo :
14800-1-AP
AntigenName :
GOT2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
FABP 1, FABPpm, Fatty acid binding protein, GOT2, KAT4, KATIV, mAspAT, mitAAT, Transaminase A
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000525
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:100 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.