This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CBS
catalog :
14787-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 36
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3a
Ahmad A, Druzhyna N, Szabo C. Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn. Burns. 2017;43:1021-1033 pubmed publisher
Wang B, Xu T, Li Y, Wang W, Lyu C, Luo D, et al. Trophoblast H2S maintains early pregnancy via regulating maternal-fetal interface immune hemostasis. J Clin Endocrinol Metab. 2020;: pubmed publisher
Zhong L, Ding W, Zeng Q, He B, Zhang H, Wang L, et al. Sodium Tanshinone IIA Sulfonate Attenuates Erectile Dysfunction in Rats with Hyperlipidemia. Oxid Med Cell Longev. 2020;2020:7286958 pubmed publisher
Zeng Q, He S, Zhong L, Wang L, Cheng F, Zhang H, et al. [Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury]. Nan Fang Yi Ke Da Xue Xue Bao. 2019;39:1329-1336 pubmed publisher
Han Y, Li Y, Hu Z, Wang X, Liu J, Ren X, et al. Hydrogen sulfide-mediated resistance against water avoidance stress-induced gastritis by maintenance of gastric microbial homeostasis. Microbiologyopen. 2019;:e951 pubmed publisher
Chen S, Yue T, Huang Z, Zhu J, Bu D, Wang X, et al. Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cells. Cancer Lett. 2019;466:49-60 pubmed publisher
Módis K, Ramanujam V, Govar A, Lopez E, Anderson K, Wang R, et al. Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis. Biochem Pharmacol. 2019;169:113604 pubmed publisher
Zou S, Shimizu T, Yamamoto M, Shimizu S, Higashi Y, Saito M. Hydrogen sulfide-induced relaxation of the bladder is attenuated in spontaneously hypertensive rats. Int Urol Nephrol. 2019;51:1507-1515 pubmed publisher
Chang L, Wang Z, Ma F, Tran B, Zhong R, Xiong Y, et al. ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway. Oxid Med Cell Longev. 2019;2019:6173685 pubmed publisher
Sun Y, Teng Z, Sun X, Zhang L, Chen J, Wang B, et al. Exogenous H2S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD+-SIRT3 pathway in cardiac tissues of db/db mice. Am J Physiol Endocrinol Metab. 2019;317:E284-E297 pubmed publisher
Sikura K, Potor L, Szerafin T, Oros M, Nagy P, Mehes G, et al. Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease. Br J Pharmacol. 2019;: pubmed publisher
Goren I, Köhler Y, Aglan A, Pfeilschifter J, Beck K, Frank S. Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes. Nitric Oxide. 2019;87:31-42 pubmed publisher
Chen S, Zuo S, Zhu J, Yue T, Bu D, Wang X, et al. Decreased expression of cystathionine β-synthase exacerbates intestinal barrier injury in ulcerative colitis. J Crohns Colitis. 2019;: pubmed publisher
Badiei A, Sudharsan R, Santana E, Dunaief J, Aguirre G. Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina. Exp Eye Res. 2019;181:72-84 pubmed publisher
Abdollahi Govar A, Töro G, Szaniszlo P, Pavlidou A, Bibli S, Thanki K, et al. 3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics. Br J Pharmacol. 2019;: pubmed publisher
Zou S, Shimizu T, Shimizu S, Higashi Y, Nakamura K, Ono H, et al. Possible role of hydrogen sulfide as an endogenous relaxation factor in the rat bladder and prostate. Neurourol Urodyn. 2018;37:2519-2526 pubmed publisher
Zhang G, Lu D, Duan S, Gao Y, Liu S, Hong Y, et al. Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways. Oxid Med Cell Longev. 2018;2018:9647809 pubmed publisher
Brown Borg H, Rakoczy S, Wonderlich J, Borg K, Rojanathammanee L. Metabolic adaptation of short-living growth hormone transgenic mice to methionine restriction and supplementation. Ann N Y Acad Sci. 2018;1418:118-136 pubmed publisher
Bellessort B, Bachelot A, Grouthier V, De Lombares C, Narboux Nême N, Garagnani P, et al. Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain. J Pain Res. 2018;11:715-725 pubmed publisher
Chen Y, Jin S, Teng X, Hu Z, Zhang Z, Qiu X, et al. Hydrogen Sulfide Attenuates LPS-Induced Acute Kidney Injury by Inhibiting Inflammation and Oxidative Stress. Oxid Med Cell Longev. 2018;2018:6717212 pubmed publisher
Pang H, Yue S, Tang Y, Chen Y, Tan Y, Cao Y, et al. Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia. Front Pharmacol. 2018;9:165 pubmed publisher
Untereiner A, Pavlidou A, Druzhyna N, Papapetropoulos A, Hellmich M, Szabo C. Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells. Biochem Pharmacol. 2018;149:174-185 pubmed publisher
Katsouda A, Szabo C, Papapetropoulos A. Reduced adipose tissue H2S in obesity. Pharmacol Res. 2018;128:190-199 pubmed publisher
Magierowski M, Magierowska K, Surmiak M, Hubalewska Mazgaj M, Kwiecien S, Wallace J, et al. The effect of hydrogen sulfide-releasing naproxen (ATB-346) versus naproxen on formation of stress-induced gastric lesions, the regulation of systemic inflammation, hypoxia and alterations in gastric microcirculation. J Physiol Pharmacol. 2017;68:749-756 pubmed
Nalli A, Wang H, Bhattacharya S, Blakeney B, Murthy K. Inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide. Pharmacol Res Perspect. 2017;5: pubmed publisher
Phillips C, Zatarain J, Nicholls M, Porter C, Widen S, Thanki K, et al. Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis. Cancer Res. 2017;77:5741-5754 pubmed publisher
Liu S, Xin D, Wang L, Zhang T, Bai X, Li T, et al. Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress. Redox Biol. 2017;13:528-540 pubmed publisher
Kuang W, Zhang X, Zhu W, Lan Z. Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium. Environ Toxicol Pharmacol. 2017;54:125-132 pubmed publisher
Untereiner A, Olah G, Módis K, Hellmich M, Szabo C. H2S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells. Biochem Pharmacol. 2017;136:86-98 pubmed publisher
Ma S, Zhong D, Ma P, Li G, Hua W, Sun Y, et al. Exogenous Hydrogen Sulfide Ameliorates Diabetes-Associated Cognitive Decline by Regulating the Mitochondria-Mediated Apoptotic Pathway and IL-23/IL-17 Expression in db/db Mice. Cell Physiol Biochem. 2017;41:1838-1850 pubmed publisher
Magierowski M, Magierowska K, Hubalewska Mazgaj M, Adamski J, Bakalarz D, Sliwowski Z, et al. Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage. Pharmacol Res. 2016;114:235-250 pubmed publisher
Gui Y, Li A, Qiu B, Chen F, Chen L, Liu D, et al. Endogenous CBS-H2S Pathway Contributes to the Development of CCI-Induced Neuropathic Pain. Neurochem Res. 2016;41:1381-9 pubmed publisher
Zhang Y, Yang J, Wang T, Wang S, Liu J, Yin C, et al. Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction. J Sex Med. 2016;13:350-60 pubmed publisher
Miyamoto R, Otsuguro K, Yamaguchi S, Ito S. Neuronal regulation of expression of hydrogen sulfide-producing enzyme cystathionine β-synthase in rat spinal cord astrocytes. Neurosci Res. 2015;97:52-9 pubmed publisher
Nalli A, Rajagopal S, Mahavadi S, Grider J, Murthy K. Inhibition of RhoA-dependent pathway and contraction by endogenous hydrogen sulfide in rabbit gastric smooth muscle cells. Am J Physiol Cell Physiol. 2015;308:C485-95 pubmed publisher
Salloum F, Sturz G, Yin C, Rehman S, Hoke N, Kukreja R, et al. Beetroot juice reduces infarct size and improves cardiac function following ischemia-reperfusion injury: Possible involvement of endogenous H2S. Exp Biol Med (Maywood). 2015;240:669-81 pubmed publisher
product information
CatalogNo :
14787-1-AP
AntigenName :
CBS
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
cystathionine-beta-synthase
Immunogen :
Recombinant Protein
Species :
dog, human, mouse, rabbit, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Beta thionase, CBS, cystathionine beta synthase, HIP4, Serine sulfhydrase
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000440
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:500 ; WB 1:2500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.