This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
MGEA5
catalog :
14711-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:500; fig 1
Nagai Okatani C, Minamino N. Aberrant Glycosylation in the Left Ventricle and Plasma of Rats with Cardiac Hypertrophy and Heart Failure. PLoS ONE. 2016;11:e0150210 pubmed publisher
Hodrea J, Balogh D, Hosszú A, Lenart L, Besztercei B, Koszegi S, et al. Reduced O-GlcNAcylation and tubular hypoxia contribute to the antifibrotic effect of SGLT2 inhibitor dapagliflozin in the diabetic kidney. Am J Physiol Renal Physiol. 2020;318:F1017-F1029 pubmed publisher
Rahman M, Hwang H, Cho Y, Rhim H. Modulation of O-GlcNAcylation Regulates Autophagy in Cortical Astrocytes. Oxid Med Cell Longev. 2019;2019:6279313 pubmed publisher
Han X, Li X, Liu H, Zhang H, Li A, Dong M, et al. O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion. Oncol Rep. 2019;42:2065-2074 pubmed publisher
Hwang J, Kim K, Park J, Kim S, Cho H, Lee Y, et al. Glucosamine improves survival in a mouse model of sepsis and attenuates sepsis-induced lung injury and inflammation. J Biol Chem. 2019;294:608-622 pubmed publisher
Lin Y, Lin C, Yeh Y, Ho H, Wu Y, Chen M, et al. High O-linked N-acetylglucosamine transferase expression predicts poor survival in patients with early stage lung adenocarcinoma. Oncotarget. 2018;9:31032-31044 pubmed publisher
Selvan N, George S, Serajee F, Shaw M, Hobson L, Kalscheuer V, et al. O-GlcNAc transferase missense mutations linked to X-linked intellectual disability deregulate genes involved in cell fate determination and signaling. J Biol Chem. 2018;293:10810-10824 pubmed publisher
Willems A, Gundogdu M, Kempers M, Giltay J, Pfundt R, Elferink M, et al. Mutations in N-acetylglucosamine (O-GlcNAc) transferase in patients with X-linked intellectual disability. J Biol Chem. 2017;292:12621-12631 pubmed publisher
Vaidyanathan K, Niranjan T, Selvan N, Teo C, May M, Patel S, et al. Identification and characterization of a missense mutation in the O-linked ?-N-acetylglucosamine (O-GlcNAc) transferase gene that segregates with X-linked intellectual disability. J Biol Chem. 2017;292:8948-8963 pubmed publisher
Gellai R, Hodrea J, Lenart L, Hosszú A, Koszegi S, Balogh D, et al. Role of O-linked N-acetylglucosamine modification in diabetic nephropathy. Am J Physiol Renal Physiol. 2016;311:F1172-F1181 pubmed publisher
Shibutani M, Mori T, Miyano T, Miyake M. Removal of O-GlcNAcylation is important for pig preimplantation development. J Reprod Dev. 2015;61:341-50 pubmed publisher
Guo X, Shang J, Deng Y, Yuan X, Zhu D, Liu H. Alterations in left ventricular function during intermittent hypoxia: Possible involvement of O-GlcNAc protein and MAPK signaling. Int J Mol Med. 2015;36:150-8 pubmed publisher
Sodi V, Khaku S, Krutilina R, Schwab L, Vocadlo D, Seagroves T, et al. mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer. Mol Cancer Res. 2015;13:923-33 pubmed publisher
Keembiyehetty C, Love D, Harwood K, Gavrilova O, Comly M, Hanover J. Conditional knock-out reveals a requirement for O-linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis. J Biol Chem. 2015;290:7097-113 pubmed publisher
Zimmerman A, Harris R. In vivo and in vitro evidence that chronic activation of the hexosamine biosynthetic pathway interferes with leptin-dependent STAT3 phosphorylation. Am J Physiol Regul Integr Comp Physiol. 2015;308:R543-55 pubmed publisher
Harris R, Apolzan J. Hexosamine biosynthetic pathway activity in leptin resistant sucrose-drinking rats. Physiol Behav. 2015;138:208-18 pubmed publisher
product information
CatalogNo :
14711-1-AP
AntigenName :
MGEA5
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
meningioma expressed antigen 5 (hyaluronidase)
Immunogen :
Recombinant Protein
Species :
drosophila, human, mouse, pig, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ChIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Beta N acetylhexosaminidase, Bifunctional protein NCOAT, HAT, HEXC, Hexosaminidase C, KIAA0679, MEA5, Meningioma expressed antigen 5, MGEA5, N acetyl beta glucosaminidase, NCOAT, O GlcNAcase, OGA
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC039583
Category :
Cytoskeleton/Scaffold Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:500 ; WB 1:4000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.