This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Collagen Type I
catalog :
14695-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry
citations: 171
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:1000; loading ...; fig 7d
Tran B, Yu Y, Chang L, Tan B, Jia W, Xiong Y, et al. A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway. Int J Nanomedicine. 2019;14:10061-10077 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 3b
Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, et al. Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro. Med Sci Monit. 2019;25:5375-5388 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 6b
  • immunocytochemistry; human; 1:50; loading ...; fig s2
  • western blot; human; 1:1000; loading ...; fig 3b
Wang M, Xiong L, Jiang L, Lu Y, Liu F, Song L, et al. miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7. EBioMedicine. 2019;41:670-682 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 4a
Wang L, Zhao R, Liu C, Liu M, Li S, Li J, et al. A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation. J Forensic Leg Med. 2016;39:138-46 pubmed publisher
Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, et al. Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease. Antioxidants (Basel). 2020;9: pubmed publisher
Wang T, Jian Z, Baskys A, Yang J, Li J, Guo H, et al. MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system. Biomaterials. 2020;257:120264 pubmed publisher
Wang Z, Zhao Y, Zhao H, Zhou J, Feng D, Tang F, et al. Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression. Mol Ther Nucleic Acids. 2020;21:751-763 pubmed publisher
Cutolo M, Soldano S, Montagna P, Martinelli G, Tardito S, Corallo C, et al. Apremilast interferes with the TGFβ1-induced transition of human skin fibroblasts into profibrotic myofibroblasts: in vitro study. Rheumatology (Oxford). 2020;: pubmed publisher
Zhang W, Ling C, Zhang A, Liu H, Jiang Y, Li X, et al. An all-silk-derived functional nanosphere matrix for sequential biomolecule delivery and in situ osteochondral regeneration. Bioact Mater. 2020;5:832-843 pubmed publisher
Wang X, Li D, Wu H, Liu F, Liu F, Zhang Q, et al. LncRNA TRPC7-AS1 regulates nucleus pulposus cellular senescence and ECM synthesis via competing with HPN for miR-4769-5p binding. Mech Ageing Dev. 2020;190:111293 pubmed publisher
Lin X, Li Y, Zhang X, Wei Y, Wen S, Lu Z, et al. Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways. Cell Biochem Funct. 2020;: pubmed publisher
Du Y, Xiao H, Wan J, Wang X, Li T, Zheng S, et al. Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts. Int J Mol Med. 2020;46:633-640 pubmed publisher
Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, et al. Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression. Biomed Pharmacother. 2020;127:110132 pubmed publisher
Tan Y, Li Y, Zhou F, Guo J, Wang T, Shi Y, et al. Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora. J Pharmacol Sci. 2020;143:165-175 pubmed publisher
Wang W, Zhang L, Guo C, Han J. Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy. Nutr Metab (Lond). 2020;17:29 pubmed publisher
Peng L, Yu M, Yang M, Liu P, Zhou H, Huang W, et al. Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction. Am J Hypertens. 2020;33:775-783 pubmed publisher
Zhao H, Lewellen B, Wilson R, Cui D, Drake J, Zhang M, et al. Long-term voluntary running prevents the onset of symptomatic Friedreich's ataxia in mice. Sci Rep. 2020;10:6095 pubmed publisher
Lv F, Li N, Kong M, Wu J, Fan Z, Miao D, et al. CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels. Front Cell Dev Biol. 2020;8:176 pubmed publisher
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, et al. TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis. J Cell Mol Med. 2020;24:5224-5237 pubmed publisher
Liu Y, Wang H, Huang Y, Weng Y, Chen R, Tsai W, et al. Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models. Biochem Pharmacol. 2020;175:113919 pubmed publisher
Zhang N, Zhang Y, Qian H, Wu S, Cao L, Sun Y. Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling. Cell Death Differ. 2020;27:2605-2619 pubmed publisher
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, et al. Silica particles disorganize the polarization of pulmonary macrophages in mice. Ecotoxicol Environ Saf. 2020;193:110364 pubmed publisher
Sun H, Zhao A, Li M, Dong H, Sun Y, Zhang X, et al. Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis. Cell Death Dis. 2020;11:146 pubmed publisher
Wang N, Xu F, Lu S, Zhang N, Sun Y. Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration. Biochem Biophys Res Commun. 2020;525:272-279 pubmed publisher
Zhou Z, Ni J, Li J, Huo C, Miao N, Yin F, et al. RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice. J Mol Med (Berl). 2020;98:527-540 pubmed publisher
Huang J, Chen C, Liang C, Luo P, Xia G, Zhang L, et al. Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development. Stem Cells Dev. 2020;29:401-413 pubmed publisher
Sun L, Qu L, Brigstock D, Li H, Li Y, Gao R. Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line. Int J Med Sci. 2020;17:137-144 pubmed publisher
Xu F, Shen X, Sun C, Xu X, Wang W, Zheng J. The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion. Med Sci Monit. 2020;26:e920670 pubmed publisher
Zhang N, Zhang Y, Wu B, You S, Sun Y. Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury. Redox Biol. 2020;30:101419 pubmed publisher
Fu S, Li Y, Wu Y, Yue Y, Yang D. Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis. J Pharm Pharmacol. 2020;72:227-235 pubmed publisher
Deng D, Pei H, Lan T, Zhu J, Tang M, Xue L, et al. Synthesis and discovery of new compounds bearing coumarin scaffold for the treatment of pulmonary fibrosis. Eur J Med Chem. 2020;185:111790 pubmed publisher
Ma N, Lu R, Zhao D, Jiang Z, Tang M, Bao C, et al. Left Atrial Appendage Fibrosis and 3-Year Clinical Outcomes in Atrial Fibrillation After Endoscopic Ablation: A Histologic Analysis. Ann Thorac Surg. 2020;109:69-76 pubmed publisher
Shao Q, Jiang C, Xia Y, Zhao M, Zhang Q, Jin B, et al. Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway. Int J Clin Exp Pathol. 2019;12:867-875 pubmed
Li Z, Chen D, Jia Y, Feng Y, Wang C, Tong Y, et al. Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway. Oxid Med Cell Longev. 2019;2019:6565283 pubmed publisher
Wang X, Lin L, Chai X, Wu Y, Li Y, Liu X. Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts. Int J Mol Med. 2019;: pubmed publisher
Chen T, Peng S, Wang Y, Hu Y, Shen Y, Xu Y, et al. Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection. Biomolecules. 2019;9: pubmed publisher
Zhang S, Hu P, Liu T, Li Z, Huang Y, Liao J, et al. Kartogenin hydrolysis product 4-aminobiphenyl distributes to cartilage and mediates cartilage regeneration. Theranostics. 2019;9:7108-7121 pubmed publisher
Zou L, Chen C, Yan X, Lin Q, Fang J, Li P, et al. Resveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways. Mol Nutr Food Res. 2019;:e1900418 pubmed publisher
Gu W, Yuan Y, Wang L, Yang H, Li S, Tang Z, et al. Long non-coding RNA TUG1 promotes airway remodelling by suppressing the miR-145-5p/DUSP6 axis in cigarette smoke-induced COPD. J Cell Mol Med. 2019;23:7200-7209 pubmed publisher
Zheng B, Fang Q, Wang X, Shi B, Zhao W, Chen C, et al. The effect of topical ramipril and losartan cream in inhibiting scar formation. Biomed Pharmacother. 2019;118:109394 pubmed publisher
Dias H, de Oliveira J, Donadio M, Kimura S. Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts. PLoS ONE. 2019;14:e0222202 pubmed publisher
Liu N, Feng J, Lu X, Yao Z, Liu Q, Lv Y, et al. Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways. Mediators Inflamm. 2019;2019:6175091 pubmed publisher
Zhang C, Zhu X, Li L, Ma T, Shi M, Yang Y, et al. A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation. Diabetes Metab Syndr Obes. 2019;12:1297-1309 pubmed publisher
Tan X, Hu L, Shu Z, Chen L, Li X, Du M, et al. Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy. Diabetes. 2019;68:2063-2073 pubmed publisher
Ge Y, Wang J, Wu D, Zhou Y, Qiu S, Chen J, et al. lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis. Mol Ther Nucleic Acids. 2019;17:741-753 pubmed publisher
Ban D, Hua S, Zhang W, Shen C, Miao X, Liu W. Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2. Cell Mol Biol Lett. 2019;24:52 pubmed publisher
Zhang Y, Yang J, Zhuan L, Zang G, Wang T, Liu J. Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats. Peerj. 2019;7:e7507 pubmed publisher
Lou L, Ni F, Chen L, Shaker S, Li W, Wang R, et al. Germacrane Sesquiterpenoids as a New Type of Anticardiac Fibrosis Agent Targeting Transforming Growth Factor β Type I Receptor. J Med Chem. 2019;: pubmed publisher
Liu Z, Zhang Y, Wang X, Fan X, Zhang Y, Li X, et al. SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition. Biomed Pharmacother. 2019;118:109227 pubmed publisher
Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, et al. Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice. Clin Sci (Lond). 2019;133:1705-1720 pubmed publisher
Du M, Duan J, Zhang C, Yang H, Guan X, Zhong W, et al. Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition. Cell Biol Int. 2019;: pubmed publisher
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, et al. Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma. EBioMedicine. 2019;45:168-180 pubmed publisher
Sun J, Su W, Zhao X, Shan T, Jin T, Guo Y, et al. LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a. Biosci Rep. 2019;39: pubmed publisher
Sun F, Zhuang Y, Zhu H, Wu H, Li D, Zhan L, et al. LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction. J Mol Cell Cardiol. 2019;: pubmed publisher
Liu H, Dong Y, Feng X, Li L, Jiao Y, Bai S, et al. miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats. Stem Cell Res Ther. 2019;10:180 pubmed publisher
Hsu Y, Chuang H, Lee Y, Lin Y, Chiu Y, Wang Y, et al. Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride. Cells. 2019;8: pubmed publisher
Yang R, Jia Q, Ma S, Wang Y, Mehmood S, Chen Y. Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway. Int J Mol Med. 2019;44:549-558 pubmed publisher
Shi A, Heinayati A, Bao D, Liu H, Ding X, Tong X, et al. Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects. Stem Cell Res Ther. 2019;10:172 pubmed publisher
Ge W, Zhang W, Gao R, Li B, Zhu H, Wang J. IMM-H007 improves heart function via reducing cardiac fibrosis. Eur J Pharmacol. 2019;857:172442 pubmed publisher
Milanesi S, Garibaldi S, Saio M, Ghigliotti G, Picciotto D, Ameri P, et al. Indoxyl Sulfate Induces Renal Fibroblast Activation through a Targetable Heat Shock Protein 90-Dependent Pathway. Oxid Med Cell Longev. 2019;2019:2050183 pubmed publisher
Liu X, Shan X, Chen H, Li Z, Zhao P, Zhang C, et al. Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis. Front Pharmacol. 2019;10:538 pubmed publisher
Yuan H, Xu J, Xu X, Gao T, Wang Y, Fan Y, et al. Calhex231 Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro. Biol Pharm Bull. 2019;42:1337-1344 pubmed publisher
Qu R, Chen X, Yuan Y, Wang W, Qiu C, Liu L, et al. Ghrelin Fights Against Titanium Particle-Induced Inflammatory Osteolysis Through Activation of β-Catenin Signaling Pathway. Inflammation. 2019;: pubmed publisher
Wang Q, Xu X, Kang Z, Zhang Z, Li Y. Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes. Artif Cells Nanomed Biotechnol. 2019;47:2139-2145 pubmed publisher
Sun X, Huang X, Zhu X, Liu L, Mo S, Wang H, et al. HBOA ameliorates CCl4-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways. Biomed Pharmacother. 2019;115:108901 pubmed publisher
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, et al. Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90. Toxicol Appl Pharmacol. 2019;371:63-73 pubmed publisher
Dong G, Liang F, Sun B, Wang C, Liu Y, Guan X, et al. Presence and function of stress granules in atrial fibrillation. PLoS ONE. 2019;14:e0213769 pubmed publisher
Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, et al. Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells. Pain Physician. 2019;22:155-164 pubmed
Gersch R, Raum J, Calvert C, Percec I. Fibroblasts Derived From Human Adipose Stem Cells Produce More Effective Extracellular Matrix and Migrate Faster Compared to Primary Dermal Fibroblasts. Aesthet Surg J. 2019;: pubmed publisher
Wang S, Xu C, Yu S, Wu X, Jie Z, Dai H. Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement. J Mech Behav Biomed Mater. 2019;94:42-50 pubmed publisher
Kong D, Zhang D, Cui Q, Wang K, Tang J, Liu Z, et al. Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro. Biomed Pharmacother. 2019;113:108706 pubmed publisher
Yao S, Xu Y, Shao C, Nudelman F, Sommerdijk N, Tang R. A Biomimetic Model for Mineralization of Type-I Collagen Fibrils. Methods Mol Biol. 2019;1944:39-54 pubmed publisher
Li K, Deng G, Deng Y, Chen S, Wu H, Cheng C, et al. High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-κB signaling. J Cell Physiol. 2019;: pubmed publisher
Zhao J, Meng M, Zhang J, Li L, Zhu X, Zhang L, et al. Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction. Mol Med Rep. 2019;19:3168-3178 pubmed publisher
Ding M, Fang Q, Cui Y, Shen Q, Liu Q, Wang P, et al. Liraglutide prevents β-cell apoptosis via inactivation of NOX2 and its related signaling pathway. J Diabetes Complications. 2019;33:267-277 pubmed publisher
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P. Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats. Gene. 2019;697:11-18 pubmed publisher
Qi H, Heise S, Zhou J, Schuhladen K, Yang Y, Cui N, et al. Electrophoretic Deposition of Bioadaptive Drug Delivery Coatings on Magnesium Alloy for Bone Repair. ACS Appl Mater Interfaces. 2019;11:8625-8634 pubmed publisher
Che X, Wu H, Jia C, Sun H, Ou S, Wang J, et al. A Novel Tissue-Engineered Corneal Stromal Equivalent Based on Amniotic Membrane and Keratocytes. Invest Ophthalmol Vis Sci. 2019;60:517-527 pubmed publisher
Wang W, Li W, Wang Y, Wang L, Mi Y, Lu J, et al. Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation. Clin Sci (Lond). 2019;133:515-530 pubmed publisher
Chen Y, Zhu D, Gao J, Xu Z, Tao S, Yin W, et al. Diminished membrane recruitment of Akt is instrumental in alcohol-associated osteopenia via the PTEN/Akt/GSK-3β/β-catenin axis. FEBS J. 2019;286:1101-1119 pubmed publisher
Zhang L, Zhang Y, Fei C, Zhang J, Wang L, Yi Z, et al. Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition. Biochem Biophys Res Commun. 2019;508:660-666 pubmed publisher
Ye M, Xu L, Fu M, Chen D, Mattina T, Zufardi O, et al. Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development. Am J Med Genet A. 2019;179:71-77 pubmed publisher
Li Y, Feng Y, Cao P, Ke J, Fang W, Cai H, et al. Role of synovium-derived fibrous cartilage in temporomandibular joint synovial chondromatosis. J Oral Pathol Med. 2019;48:79-86 pubmed publisher
Dou F, Liu Y, Liu L, Wang J, Sun T, Mu F, et al. Aloe-Emodin Ameliorates Renal Fibrosis Via Inhibiting PI3K/Akt/mTOR Signaling Pathway In Vivo and In Vitro. Rejuvenation Res. 2019;22:218-229 pubmed publisher
Liu T, Xu L, Wang C, Chen K, Xia Y, Li J, et al. Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin. J Gastroenterol Hepatol. 2019;34:263-276 pubmed publisher
Deng Z, Li W, Xu J, Yu M, Li D, Tan Q, et al. ClC-3 chloride channels are involved in estradiol regulation of bone formation by MC3T3-E1 osteoblasts. J Cell Biochem. 2018;: pubmed publisher
Zhu J, Wang R, Xu T, Zhang S, Zhao Y, Li Z, et al. Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway. Front Pharmacol. 2018;9:1277 pubmed publisher
Li H, Ma N, Wang J, Wang Y, Yuan C, Wu J, et al. Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization. Technol Cancer Res Treat. 2018;17:1533033818809984 pubmed publisher
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, et al. CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice. Biomed Pharmacother. 2018;108:1640-1650 pubmed publisher
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X. Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro. Med Sci Monit. 2018;24:7654-7664 pubmed publisher
Deng G, Li K, Chen S, Chen P, Zheng H, Yu B, et al. Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro. Mol Med Rep. 2018;18:5044-5052 pubmed publisher
Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, et al. Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem. Nat Commun. 2018;9:3390 pubmed publisher
Yu Y, Liu D, Liu Z, Li S, Ge Y, Sun W, et al. The inhibitory effects of COL1A2 on colorectal cancer cell proliferation, migration, and invasion. J Cancer. 2018;9:2953-2962 pubmed publisher
Zhang C, Liu X, Sun H, Meng X, Bao Y, Zhang H, et al. Octreotide attenuates hepatic fibrosis and hepatic stellate cells proliferation and activation by inhibiting Wnt/β-catenin signaling pathway, c-Myc and cyclin D1. Int Immunopharmacol. 2018;63:183-190 pubmed publisher
Chang S, Hsiao Y, Tsai Y, Lin S, Liu S, Lin Y, et al. Interleukin-17 enhances cardiac ventricular remodeling via activating MAPK pathway in ischemic heart failure. J Mol Cell Cardiol. 2018;122:69-79 pubmed publisher
Zhao X, Sun J, Chen Y, Su W, Shan H, Li Y, et al. lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis. Mol Ther. 2018;26:2206-2217 pubmed publisher
Qin W, Liu B, Yi M, Li L, Tang Y, Wu B, et al. Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model. Radiat Res. 2018;190:396-403 pubmed publisher
Zhou B, Ling L, Zhang F, Liu T, Zhou H, Qi X, et al. Fibronectin Type III Domain-Containing 5 Attenuates Liver Fibrosis Via Inhibition of Hepatic Stellate Cell Activation. Cell Physiol Biochem. 2018;48:227-236 pubmed publisher
Liu Z, Zhang Z, Huang M, Sun X, Liu B, Guo Q, et al. Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments. BMC Gastroenterol. 2018;18:112 pubmed publisher
Zhao X, Qu G, Song C, Li R, Liu W, Lv C, et al. Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway. Toxicol Appl Pharmacol. 2018;356:15-24 pubmed publisher
Xu W, Li J, Zhang W, Wang Z, Wu J, Ge X, et al. Emission of sulfur dioxide from polyurethane foam and respiratory health effects. Environ Pollut. 2018;242:90-97 pubmed publisher
Wu J, Liu J, Ding Y, Zhu M, Lu K, Zhou J, et al. MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy. Biochem Biophys Res Commun. 2018;503:977-983 pubmed publisher
Yang W, Chen Q, Xia R, Zhang Y, Shuai L, Lai J, et al. A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation. Biomaterials. 2018;177:52-66 pubmed publisher
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, et al. Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis. Biomed Pharmacother. 2018;103:1262-1271 pubmed publisher
Altieri P, Bertolotto M, Fabbi P, Sportelli E, Balbi M, Santini F, et al. Thrombin induces protease-activated receptor 1 signaling and activation of human atrial fibroblasts and dabigatran prevents these effects. Int J Cardiol. 2018;271:219-227 pubmed publisher
Luo X, Wang D, Zhu X, Wang G, You Y, Ning Z, et al. Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration. Cell Death Dis. 2018;9:576 pubmed publisher
Lee H, Feliers D, Barnes J, Oh S, Choudhury G, Diaz V, et al. Hydrogen sulfide ameliorates aging-associated changes in the kidney. GeroScience. 2018;40:163-176 pubmed publisher
Li X, Yu T, Shan H, Jiang H, Sun J, Zhao X, et al. lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a. FASEB J. 2018;32:5285-5297 pubmed publisher
Zhao X, Sun J, Su W, Shan H, Zhang B, Wang Y, et al. Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway. Int J Mol Sci. 2018;19: pubmed publisher
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, et al. Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model. Chin Med. 2018;13:17 pubmed publisher
Chen S, Deng G, Li K, Zheng H, Wang G, Yu B, et al. Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells. Med Sci Monit. 2018;24:1567-1573 pubmed
Liu X, Zhang Y, Shi M, Wang Y, Zhang F, Yan R, et al. Notch1 regulates PTEN expression to exacerbate renal tubulointerstitial fibrosis in diabetic nephropathy by inhibiting autophagy via interactions with Hes1. Biochem Biophys Res Commun. 2018;497:1110-1116 pubmed publisher
Li Z, Ding Q, Ling L, Wu Y, Meng D, Li X, et al. Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase. World J Gastroenterol. 2018;24:819-832 pubmed publisher
Liang H, Pan Z, Zhao X, Liu L, Sun J, Su X, et al. LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d. Theranostics. 2018;8:1180-1194 pubmed publisher
Lai T, Li Y, Mai Z, Wen X, Lv Y, Xie Z, et al. Annexin A1 is elevated in patients with COPD and affects lung fibroblast function. Int J Chron Obstruct Pulmon Dis. 2018;13:473-486 pubmed publisher
Sun L, Xiu M, Wang S, Brigstock D, Li H, Qu L, et al. Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis. J Cell Mol Med. 2018;22:2346-2356 pubmed publisher
Zhang X, Ma Z, Yuan Y, Xu S, Wei W, Song P, et al. Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling. Cell Death Dis. 2018;9:102 pubmed publisher
Zhao W, Yang A, Chen W, Wang P, Liu T, Cong M, et al. Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1129-1137 pubmed publisher
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product information
CatalogNo :
14695-1-AP
AntigenName :
Collagen Type I
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
collagen, type I, alpha 2
Immunogen :
Recombinant Protein
Species :
dog, human, mouse, pig, porcine, rabbit, rat, toad
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Alpha 2 type I collagen, COL1A2, Collagen alpha 2(I) chain, Collagen Type I, collagen, type I, alpha 2, OI4
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC054498
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.