This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
ERCC1
catalog :
14586-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 9
Reference
Tan L, Li X, Qiu C, Zhu T, Hu C, Yin J, et al. CLEC4M is associated with poor prognosis and promotes cisplatin resistance in NSCLC patients. J Cancer. 2019;10:6374-6383 pubmed publisher
Li J, Jiang G, Zhao L, Yang F, Yuan W, Wang H, et al. Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression. Oncol Rep. 2019;: pubmed publisher
Gao X, Wang J, Li M, Wang J, Lv J, Zhang L, et al. Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs. J Cell Mol Med. 2019;: pubmed publisher
Jing C, Li H, Du Y, Cao H, Liu S, Wang Z, et al. MEK inhibitor enhanced the antitumor effect of oxaliplatin and 5‑fluorouracil in MEK1 Q56P‑mutant colorectal cancer cells. Mol Med Rep. 2019;19:1092-1100 pubmed publisher
Shi W, Zhu X, Wang C, Zhang Y, Cai H, Li X, et al. PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT. Cell Death Dis. 2018;9:428 pubmed publisher
Liu J, Zhang L, Mao P, Jiang G, Liu L, Wang J, et al. Functional characterization of a novel transcript of ERCC1 in chemotherapy resistance of ovarian cancer. Oncotarget. 2017;8:85759-85771 pubmed publisher
Wang W, Zhang L, Liu L, Zheng Y, Zhang Y, Yang S, et al. Chemosensitizing effect of shRNA-mediated ERCC1 silencing on a Xuanwei lung adenocarcinoma cell line and its clinical significance. Oncol Rep. 2017;37:1989-1997 pubmed publisher
Wang L, Wang Y, Guan Q, Liu Y, He T, Wang J. Establishment of a first-line second-line treatment model for human pulmonary adenocarcinoma. Oncol Lett. 2016;12:4461-4466 pubmed publisher
Dong H, Shi Q, Song X, Fu J, Hu L, Xu D, et al. Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis. Toxicol Appl Pharmacol. 2015;286:10-6 pubmed publisher
product information
CatalogNo :
14586-1-AP
AntigenName :
ERCC1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
COFS4, ERCC1, UV20
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC052813
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Disease Related;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:50 ; IP 1:300 ; WB 1:2500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.