This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
AFP
catalog :
14550-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 31
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 3d
Cao J, Zhao M, Liu J, Zhang X, Pei Y, Wang J, et al. RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog. Theranostics. 2019;9:811-828 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1h
Okashita N, Suwa Y, Nishimura O, Sakashita N, Kadota M, Nagamatsu G, et al. PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency. Stem Cell Reports. 2016;7:1072-1086 pubmed publisher
Li Q, Qiu M, Yang S, Fang X, He X, Wang M, et al. Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells. J Oncol. 2020;2020:9327512 pubmed publisher
Wang J, Cui Y, Xing K, Luan J, Han J. Generation and characterization of a human iPSC line derived from congenital clubfoot amniotic fluid cells. Stem Cell Res. 2020;43:101712 pubmed publisher
Xue J, Cao Z, Cheng Y, Wang J, Liu Y, Yang R, et al. Acetylation of alpha-fetoprotein promotes hepatocellular carcinoma progression. Cancer Lett. 2020;471:12-26 pubmed publisher
Hiramatsu N, Yamamoto N, Isogai S, Onouchi T, Hirayama M, Maeda S, et al. An analysis of monocytes and dendritic cells differentiated from human peripheral blood monocyte-derived induced pluripotent stem cells. Med Mol Morphol. 2019;: pubmed publisher
Liu Z, Lu Z, Jing R, Zuo B, Gao X, Han G, et al. Alarmin augments the antitumor immunity of lentiviral vaccine in ectopic, orthotopic and autochthonous hepatocellular carcinoma mice. Theranostics. 2019;9:4006-4018 pubmed publisher
Xue R, Chen L, Zhang C, Fujita M, Li R, Yan S, et al. Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes. Cancer Cell. 2019;: pubmed publisher
Zhao Z, Xiong S, Wang R, Li Y, Wang X, Wang Y, et al. Peri-tumor fibroblasts promote tumorigenesis and metastasis of hepatocellular carcinoma via Interleukin6/STAT3 signaling pathway. Cancer Manag Res. 2019;11:2889-2901 pubmed publisher
Bi Y, Han W, Li R, Wang Y, Du Z, Wang X, et al. Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions. World J Gastroenterol. 2019;25:1936-1949 pubmed publisher
Watanabe K, Yamamoto M, Xin B, Ooshio T, Goto M, Fujii K, et al. Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations. Hepatol Commun. 2019;3:697-715 pubmed publisher
Dai Y, Zhu L, Zhang Y, Wang S, Chen K, Jiang T, et al. Au@SiO2@CuInS2-ZnS/Anti-AFP fluorescent probe improves HCC cell labeling. Hepatobiliary Pancreat Dis Int. 2019;18:266-272 pubmed publisher
Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, et al. TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma. Am J Pathol. 2019;189:1077-1090 pubmed publisher
Zong L, Peng H, Sun C, Li F, Zheng M, Chen Y, et al. Breakdown of adaptive immunotolerance induces hepatocellular carcinoma in HBsAg-tg mice. Nat Commun. 2019;10:221 pubmed publisher
Ye Y, Song Y, Zhuang J, Wang G, Ni J, Xia W. Anticancer effects of echinacoside in hepatocellular carcinoma mouse model and HepG2 cells. J Cell Physiol. 2019;234:1880-1888 pubmed publisher
Xu A, Wang B, Fu J, Qin W, Yu T, Yang Z, et al. Diet-induced hepatic steatosis activates Ras to promote hepatocarcinogenesis via CPT1α. Cancer Lett. 2018;442:40-52 pubmed publisher
Chen L, Guo P, He Y, Chen Z, Chen L, Luo Y, et al. HCC-derived exosomes elicit HCC progression and recurrence by epithelial-mesenchymal transition through MAPK/ERK signalling pathway. Cell Death Dis. 2018;9:513 pubmed publisher
Hernandez C, Huebener P, Pradere J, Antoine D, Friedman R, Schwabe R. HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis. J Clin Invest. 2018;128:2436-2451 pubmed publisher
Cai Z, Qian Z, Jiang H, Ma N, Li Z, Liu L, et al. hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating β-Catenin Signaling. Cancer Res. 2018;78:2536-2549 pubmed publisher
Yamamoto M, Xin B, Watanabe K, Ooshio T, Fujii K, Chen X, et al. Oncogenic Determination of a Broad Spectrum of Phenotypes of Hepatocyte-Derived Mouse Liver Tumors. Am J Pathol. 2017;187:2711-2725 pubmed publisher
Nault R, Fader K, Harkema J, Zacharewski T. Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice. PLoS ONE. 2017;12:e0184842 pubmed publisher
Sun J, Hu T, Xu X, Wang L, Yang X. A fluorescent ELISA based on the enzyme-triggered synthesis of poly(thymine)-templated copper nanoparticles. Nanoscale. 2016;8:16846-16850 pubmed
Wang F, Huang J, Zhu Z, Ma X, Cao L, Zhang Y, et al. Transcriptome Analysis of WHV/c-myc Transgenic Mice Implicates Cytochrome P450 Enzyme 17A1 as a Promising Biomarker for Hepatocellular Carcinoma. Cancer Prev Res (Phila). 2016;9:739-49 pubmed publisher
Mu X, Español Suñer R, Mederacke I, Affò S, Manco R, Sempoux C, et al. Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment. J Clin Invest. 2015;125:3891-903 pubmed publisher
Okashita N, Sakashita N, Ito K, Mitsuya A, Suwa Y, Seki Y. PRDM14 maintains pluripotency of embryonic stem cells through TET-mediated active DNA demethylation. Biochem Biophys Res Commun. 2015;466:138-45 pubmed publisher
Zhang F, Li L, Yang X, Wang B, Zhao J, Lu S, et al. Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3'-methyl-4 dimethylaminoazobenzene in rats. J Toxicol Pathol. 2015;28:79-87 pubmed publisher
Chen X, Yamamoto M, Fujii K, Nagahama Y, Ooshio T, Xin B, et al. Differential reactivation of fetal/neonatal genes in mouse liver tumors induced in cirrhotic and non-cirrhotic conditions. Cancer Sci. 2015;106:972-81 pubmed publisher
Yuan J, Jiang B, Zhang A, Qian Y, Tan H, Gao J, et al. Accelerated hepatocellular carcinoma development in CUL4B transgenic mice. Oncotarget. 2015;6:15209-21 pubmed
Hou R, Wang Y, Liang H, Zhang Z, Liu Z, Zhang B, et al. Animal and cellular models of hepatocellular carcinoma bone metastasis: establishment and characterisation. J Cancer Res Clin Oncol. 2015;141:1931-43 pubmed publisher
Bertram K, Valcu C, Weitnauer M, Linne U, Görlach A. NOX1 supports the metabolic remodeling of HepG2 cells. PLoS ONE. 2015;10:e0122002 pubmed publisher
Tsujiwaki M, Murata M, Takasawa A, Hiratsuka Y, Fukuda R, Sugimoto K, et al. Aberrant expression of claudin-4 and -7 in hepatocytes in the cirrhotic human liver. Med Mol Morphol. 2015;48:33-43 pubmed publisher
product information
CatalogNo :
14550-1-AP
AntigenName :
AFP
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
alpha-fetoprotein
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
AFP, Alpha 1 fetoprotein, Alpha fetoglobulin, alpha fetoprotein, FETA, HPAFP
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC027881
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Disease Related;IVD;Oncogene(s) and Tumor Suppressor(s);Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:50 ; IHC 1:50 ; IP 1:1000 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.