This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
TOM70
catalog :
14528-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 4b
Momcilovic M, Jones A, Bailey S, Waldmann C, Li R, Lee J, et al. In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. 2019;575:380-384 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig e3b
Hoshino A, Wang W, Wada S, McDermott Roe C, Evans C, Gosis B, et al. The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. Nature. 2019;575:375-379 pubmed publisher
  • western blot; human; fig 8
Kang Y, Baker M, Liem M, Louber J, McKenzie M, Atukorala I, et al. Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. elife. 2016;5: pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 5A
  • western blot; mouse; 1:1000; fig 7B
Sin J, Andres A, Taylor D, Weston T, Hiraumi Y, Stotland A, et al. Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts. Autophagy. 2016;12:369-80 pubmed publisher
Tsai Y, Coady T, Lu L, Zheng D, Alland I, Tian B, et al. ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs. Genes Dev. 2020;34:785-805 pubmed publisher
Taylor D, Hamid S, Andres A, Saadaeijahromi H, Piplani H, Germano J, et al. Antiviral Effects of Menthol on Coxsackievirus B. Viruses. 2020;12: pubmed publisher
Scott H, Buckner N, Fernández Albert F, Pedone E, Postiglione L, Shi G, et al. A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria. J Biol Chem. 2020;: pubmed publisher
Wei X, Du M, Xie J, Luo T, Zhou Y, Zhang K, et al. Mutations in TOMM70 lead to multi-OXPHOS deficiencies and cause severe anemia, lactic acidosis, and developmental delay. J Hum Genet. 2020;65:231-240 pubmed publisher
Hira S, Packialakshmi B, Zhou X. EAE-induced upregulation of mitochondrial MnSOD is associated with increases of mitochondrial SGK1 and Tom20 protein in the mouse kidney cortex. J Physiol Sci. 2019;: pubmed publisher
Wang J, Wang K, Huang C, Lin D, Zhou Y, Wu Y, et al. SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis. Int J Biol Sci. 2018;14:1873-1882 pubmed publisher
Zhou B, Zhang J, Liu X, Chen H, Ai Y, Cheng K, et al. Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis. Cell Res. 2018;28:1171-1185 pubmed publisher
Branon T, Bosch J, Sanchez A, Udeshi N, Svinkina T, Carr S, et al. Efficient proximity labeling in living cells and organisms with TurboID. Nat Biotechnol. 2018;36:880-887 pubmed publisher
Noh J, Kim K, Idda M, Martindale J, Yang X, Abdelmohsen K, et al. GRSF1 suppresses cell senescence. Aging (Albany NY). 2018;10:1856-1866 pubmed publisher
Huang S, Wang X, Wu X, Yu J, Li J, Huang X, et al. Yap regulates mitochondrial structural remodeling during myoblast differentiation. Am J Physiol Cell Physiol. 2018;315:C474-C484 pubmed publisher
Sin J, McIntyre L, Stotland A, Feuer R, Gottlieb R. Coxsackievirus B Escapes the Infected Cell in Ejected Mitophagosomes. J Virol. 2017;91: pubmed publisher
Andres A, Tucker K, Thomas A, Taylor D, Sengstock D, Jahania S, et al. Mitophagy and mitochondrial biogenesis in atrial tissue of patients undergoing heart surgery with cardiopulmonary bypass. JCI Insight. 2017;2:e89303 pubmed publisher
Martinez Lyons A, Ardissone A, Reyes A, Robinson A, Moroni I, Ghezzi D, et al. COA7 (C1orf163/RESA1) mutations associated with mitochondrial leukoencephalopathy and cytochrome c oxidase deficiency. J Med Genet. 2016;53:846-849 pubmed publisher
Spadafora D, Kozhukhar N, Alexeyev M. Presequence-Independent Mitochondrial Import of DNA Ligase Facilitates Establishment of Cell Lines with Reduced mtDNA Copy Number. PLoS ONE. 2016;11:e0152705 pubmed publisher
Xu S, Cherok E, Das S, Li S, Roelofs B, Ge S, et al. Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein. Mol Biol Cell. 2016;27:349-59 pubmed publisher
Kazlauskaite A, Martínez Torres R, Wilkie S, Kumar A, Peltier J, González A, et al. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation. EMBO Rep. 2015;16:939-54 pubmed publisher
Lam S, Martell J, Kamer K, Deerinck T, Ellisman M, Mootha V, et al. Directed evolution of APEX2 for electron microscopy and proximity labeling. Nat Methods. 2015;12:51-4 pubmed publisher
product information
CatalogNo :
14528-1-AP
AntigenName :
TOM70
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
KIAA0719, TOM70, TOM70, TOMM70A
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC052994
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:100 ; IHC 1:50 ; IP 1:500 ; WB 1:1500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.