This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SREBF2
catalog :
14508-1-AP
quantity :
150 ul
price :
279 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, chicken
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 6b
Hsieh J, Koseki M, Molusky M, Yakushiji E, Ichi I, Westerterp M, et al. TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis. Nature. 2016;535:303-7 pubmed publisher
Jiang Y, Fu C, Liu G, Guo J, Su Z. Cholesterol-lowering effects and potential mechanisms of chitooligosaccharide capsules in hyperlipidemic rats. Food Nutr Res. 2018;62: pubmed publisher
Wang S, Tian M, Yang R, Jing Y, Chen W, Wang J, et al. 6-Gingerol Ameliorates Behavioral Changes and Atherosclerotic Lesions in ApoE-/- Mice Exposed to Chronic Mild Stress. Cardiovasc Toxicol. 2018;18:420-430 pubmed publisher
Wang Y, Wu T, Hu D, Weng X, Wang X, Chen P, et al. Intracellular hepatitis B virus increases hepatic cholesterol deposition in alcoholic fatty liver via hepatitis B core protein. J Lipid Res. 2018;59:58-68 pubmed publisher
Kuang W, Zhang X, Lan Z. Flavonoids extracted from Linaria vulgaris protect against hyperlipidemia and hepatic steatosis induced by western-type diet in mice. Arch Pharm Res. 2018;41:1190-1198 pubmed publisher
Yang T, Yao H, Chiang M. Red algae (Gelidium amansii) hot-water extract ameliorates lipid metabolism in hamsters fed a high-fat diet. J Food Drug Anal. 2017;25:931-938 pubmed publisher
Hu Y, Sun Q, Zong Y, Liu J, Idriss A, Omer N, et al. Prenatal betaine exposure alleviates corticosterone-induced inhibition of CYP27A1 expression in the liver of juvenile chickens associated with its promoter DNA methylation. Gen Comp Endocrinol. 2017;246:241-248 pubmed publisher
He K, Li X, Xiao Y, Yong Y, Zhang Z, Li S, et al. Hypolipidemic effects of Myrica rubra extracts and main compounds in C57BL/6j mice. Food Funct. 2016;7:3505-15 pubmed publisher
He K, Hu Y, Ma H, Zou Z, Xiao Y, Yang Y, et al. Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways. Biochim Biophys Acta. 2016;1862:1696-709 pubmed publisher
Hu Y, Wu S, Zhao J, Ma X, Lu J, Xiu J, et al. VNN1 promotes atherosclerosis progression in apoE-/- mice fed a high-fat/high-cholesterol diet. J Lipid Res. 2016;57:1398-411 pubmed publisher
Han J, Li E, Chen L, Zhang Y, Wei F, Liu J, et al. The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1. Nature. 2015;524:243-6 pubmed publisher
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, et al. Potent effects of dioscin against obesity in mice. Sci Rep. 2015;5:7973 pubmed publisher
He K, Ye X, Wu H, Wang Y, Zou Z, Ning N, et al. The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters. Lipids. 2015;50:185-94 pubmed publisher
Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, et al. Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats. Food Funct. 2014;5:3065-75 pubmed publisher
Hu Y, Zhao J, Li S, Huang J, Qiu Y, Ma X, et al. RP5-833A20.1/miR-382-5p/NFIA-dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction. Arterioscler Thromb Vasc Biol. 2015;35:87-101 pubmed publisher
Yan H, Ma Y, Gui Y, Wang S, Wang X, Gao F, et al. MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression. Acta Pharmacol Sin. 2014;35:994-1004 pubmed publisher
Hu Y, Yang J, Ma X, Chen Z, Hu Y, Zhao J, et al. A lincRNA-DYNLRB2-2/GPR119/GLP-1R/ABCA1-dependent signal transduction pathway is essential for the regulation of cholesterol homeostasis. J Lipid Res. 2014;55:681-97 pubmed publisher
Fryer L, Jones B, Duncan E, Hutchison C, Ozkan T, Williams P, et al. The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis. J Biol Chem. 2014;289:4244-61 pubmed publisher
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, et al. Protective effects of dioscin against alcohol-induced liver injury. Arch Toxicol. 2014;88:739-53 pubmed publisher
Zhang S, Zheng L, Dong D, Xu L, Yin L, Qi Y, et al. Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats. Food Chem. 2013;141:2108-16 pubmed publisher
Hu Y, Ma X, Huang J, Mao X, Yang J, Zhao J, et al. Dihydrocapsaicin Attenuates Plaque Formation through a PPAR?/LXR? Pathway in apoE(-/-) Mice Fed a High-Fat/High-Cholesterol Diet. PLoS ONE. 2013;8:e66876 pubmed publisher
product information
Catalog Number :
14508-1-AP
Item Name :
SREBF2
Quantity / Package Size :
150 ul
Price :
279 USD
20ul trial size available :
20ul trial size available
FullName :
sterol regulatory element binding transcription factor 2
Antigen :
Recombinant Protein
Species Reactivity :
chicken, hamster, hamsters, human, mouse, rat
Host Species :
Rabbit
Conjugate :
Unconjugated
Antigen Species :
human
Applications :
WB, IP, IHC, ELISA
Type :
Polyclonal
Isotype :
IgG
Antigen Synonyms :
bHLHd2, SREBF2, SREBP 2, SREBP2
Primary or Secondary? :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC056158
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Disease Related;Membrane Proteins;Metabolism;
Form/Purification :
Antigen affinity purification
IsSellable :
1
AppTiter :
IHC 1:200 ; IP 1:500 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.