This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CEP250/CNAP1
catalog :
14498-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 15
Reference
Pizon V, Gaudin N, Poteau M, Cifuentes Diaz C, Demdou R, Heyer V, et al. hVFL3/CCDC61 is a component of mother centriole subdistal appendages required for centrosome cohesion and positioning. Biol Cell. 2020;112:22-37 pubmed publisher
Gwon D, Hong J, Jang C. c-Cbl Acts as an E3 Ligase Against DDA3 for Spindle Dynamics and Centriole Duplication during Mitosis. Mol Cells. 2019;42:840-849 pubmed publisher
So C, Seres K, Steyer A, Mönnich E, Clift D, Pejkovska A, et al. A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes. Science. 2019;364: pubmed publisher
Busselez J, Chichon F, Rodriguez M, Alpizar A, Gharbi S, Franch M, et al. Cryo-Electron Tomography and Proteomics studies of centrosomes from differentiated quiescent thymocytes. Sci Rep. 2019;9:7187 pubmed publisher
Kim S, Gwon D, Kim J, Choi H, Jang C. Bisphenol A disrupts mitotic progression via disturbing spindle attachment to kinetochore and centriole duplication in cancer cell lines. Toxicol In Vitro. 2019;59:115-125 pubmed publisher
Tu H, Qin X, Liu Z, Song Z, Hu H, Zhang Y, et al. Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis. Nat Commun. 2018;9:5277 pubmed publisher
Sydor A, Coyaud E, Rovelli C, Laurent E, Liu H, Raught B, et al. PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN. elife. 2018;7: pubmed publisher
Simerly C, Manil Ségalen M, Castro C, Hartnett C, Kong D, Verlhac M, et al. Separation and Loss of Centrioles From Primordidal Germ Cells To Mature Oocytes In The Mouse. Sci Rep. 2018;8:12791 pubmed publisher
Yaguchi K, Yamamoto T, Matsui R, Tsukada Y, Shibanuma A, Kamimura K, et al. Uncoordinated centrosome cycle underlies the instability of non-diploid somatic cells in mammals. J Cell Biol. 2018;217:2463-2483 pubmed publisher
Mahen R. Stable centrosomal roots disentangle to allow interphase centriole independence. PLoS Biol. 2018;16:e2003998 pubmed publisher
Mori M, Hazan R, Danielian P, Mahoney J, Li H, LU J, et al. Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis. Nat Commun. 2017;8:15857 pubmed publisher
de Castro Miró M, Tonda R, Escudero Ferruz P, Andres R, Mayor Lorenzo A, Castro J, et al. Novel Candidate Genes and a Wide Spectrum of Structural and Point Mutations Responsible for Inherited Retinal Dystrophies Revealed by Exome Sequencing. PLoS ONE. 2016;11:e0168966 pubmed publisher
Cervenka I, Valnohova J, Bernatik O, Harnoš J, Radsetoulal M, Sedova K, et al. Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins. Proc Natl Acad Sci U S A. 2016;113:9304-9 pubmed publisher
Martino J, Holmes A, Xie H, Wise S, Wise J. Chronic Exposure to Particulate Chromate Induces Premature Centrosome Separation and Centriole Disengagement in Human Lung Cells. Toxicol Sci. 2015;147:490-9 pubmed publisher
Zhang Y, Wang Y, Wei Y, Ma J, Peng J, Wumaier R, et al. The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly. Biochem Biophys Res Commun. 2015;458:494-500 pubmed publisher
product information
CatalogNo :
14498-1-AP
AntigenName :
CEP250/CNAP1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
centrosomal protein 250kDa
Immunogen :
Recombinant Protein
Species :
human, mouse
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
250 kDa centrosomal protein, C NAP1, Centrosomal protein 2, centrosomal protein 250kDa, CEP2, CEP250, CNAP1, C-NAP1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC001433
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:500 ; WB 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.