This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
ATP1A1
catalog :
14418-1-AP
quantity :
150UL
price :
99 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 42
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 8e
Xu Y, Zhu J, Hu X, Wang C, Lu D, Gong C, et al. CLIC1 Inhibition Attenuates Vascular Inflammation, Oxidative Stress, and Endothelial Injury. PLoS ONE. 2016;11:e0166790 pubmed publisher
Huang W, Zhang Y, Xu Y, Yang S, Li B, Huang L, et al. Comprehensive analysis of the expression of sodium/potassium-ATPase α subunits and prognosis of ovarian serous cystadenocarcinoma. Cancer Cell Int. 2020;20:309 pubmed publisher
Wan X, Ma B, Wang X, Guo C, Sun J, Cui J, et al. S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes. J Alzheimers Dis. 2020;76:981-995 pubmed publisher
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, et al. Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biol. 2020;32:101514 pubmed publisher
Wu W, Wang S, Liu Q, Shan T, Wang X, Feng J, et al. AMPK facilitates intestinal long-chain fatty acid uptake by manipulating CD36 expression and translocation. FASEB J. 2020;34:4852-4869 pubmed publisher
Chen J, Li H, Li T, Fu W, Du X, Liu C, et al. Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes. BMC Complement Med Ther. 2020;20:22 pubmed publisher
Su H, Ye C, Lei C, Tang H, Zeng J, Yi F, et al. Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure. FASEB J. 2020;34:1620-1636 pubmed publisher
Morimoto M, Horikoshi Y, Nakaso K, Kurashiki T, Kitagawa Y, Hanaki T, et al. Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer. Cancer Lett. 2020;470:149-160 pubmed publisher
Xue M, Liang H, Ji X, Liu Y, Ge Y, Hou L, et al. Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology. Nutr Metab (Lond). 2019;16:87 pubmed publisher
Chen R, Xu X, Liu F, Li C, Li Y, Li X, et al. The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling. Front Oncol. 2019;9:1347 pubmed publisher
Yang X, Li S, Zhao Y, Li S, Zhao T, Tai Y, et al. GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice. Cells. 2019;8: pubmed publisher
Lan Y, Chen C, Wang X, Lou J, Xing J, Zou S, et al. Gamabufotalin induces a negative feedback loop connecting ATP1A3 expression and the AQP4 pathway to promote temozolomide sensitivity in glioblastoma cells by targeting the amino acid Thr794. Cell Prolif. 2019;:e12732 pubmed publisher
Zhang J, Li S, Deng F, Baikeli B, Yu W, Liu G. Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis. Sci Rep. 2019;9:16639 pubmed publisher
Xu T, Yu X, Deng J, Ou S, Liu X, Wang T, et al. CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells. Cell Death Dis. 2019;10:825 pubmed publisher
Tang X, Zhang X, Li S, Chi X, Luo A, Zhao Y. NR2B receptor- and calpain-mediated KCC2 cleavage resulted in cognitive deficiency exposure to isoflurane. Neurotoxicology. 2019;76:75-83 pubmed publisher
Fujimoto B, Young M, Carter L, Pang A, Corley M, Fogelgren B, et al. The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells. Am J Physiol Endocrinol Metab. 2019;317:E957-E972 pubmed publisher
Lu Z, Shi Z, Dang Y, Cheng Y, Guan Y, Hao Z, et al. Pantoprazole pretreatment elevates sensitivity to vincristine in drug-resistant oral epidermoid carcinoma in vitro and in vivo. Biomed Pharmacother. 2019;120:109478 pubmed publisher
Zhang H, Tian X, Lu X, Xu D, Guo Y, Dong Z, et al. TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation. J Clin Invest. 2019;129:3864-3876 pubmed publisher
Xiao Y, Zhang J, Shu X, Bai L, Xu W, Wang A, et al. Loss of mitochondrial protein CHCHD10 in skeletal muscle causes neuromuscular junction impairment. Hum Mol Genet. 2019;: pubmed publisher
Yan Y, Yu H, Sun L, Liu H, Wang C, Wei X, et al. Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract. Aging (Albany NY). 2019;11:2699-2723 pubmed publisher
Yang X, Zhao Y, Jia X, Wang C, Wu Y, Zhang L, et al. CP-25 combined with MTX/ LEF ameliorates the progression of adjuvant-induced arthritis by the inhibition on GRK2 translocation. Biomed Pharmacother. 2019;110:834-843 pubmed publisher
Tian Y, Yang T, Yu S, Liu C, He M, Hu C. Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels. J Cell Mol Med. 2018;22:6327-6337 pubmed publisher
Tao Z, Li T, Ma H, Yang Y, Zhang C, Hai L, et al. Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation. Cell Death Dis. 2018;9:1063 pubmed publisher
Berges R, Denicolaï E, Tchoghandjian A, Baeza Kallee N, Honore S, Figarella Branger D, et al. Proscillaridin A exerts anti-tumor effects through GSK3? activation and alteration of microtubule dynamics in glioblastoma. Cell Death Dis. 2018;9:984 pubmed publisher
Zhao Q, Lu J, Li Z, Mei Y. Neuritin promotes neurite and spine growth in rat cerebellar granule cells via L-type calcium channel-mediated calcium influx. J Neurochem. 2018;147:40-57 pubmed publisher
Lu Y, Li L, Yang Y, Yin X, Liu Q, Zhang L, et al. Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling. Cell Death Dis. 2018;9:672 pubmed publisher
Zheng J, Wang Y, Han S, Luo Y, Sun X, Zhu N, et al. Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice. J Diabetes Res. 2018;2018:8431249 pubmed publisher
Yan X, Xun M, Wu L, Du X, Zhang F, Zheng J. DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na+-K+-ATPase, inhibiting Na+-K+-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2. Toxicol Appl Pharmacol. 2018;349:62-71 pubmed publisher
Zhou Y, Wu F, Zhang M, Xiong Z, Yin Q, Ru Y, et al. EMC10 governs male fertility via maintaining sperm ion balance. J Mol Cell Biol. 2018;10:503-514 pubmed publisher
Zhang J, Yan M, Gu W, Chen A, Liu J, Li L, et al. Downregulation of Aquaporins (AQP1 and AQP5) and Na,K-ATPase in Porcine Reproductive and Respiratory Syndrome Virus-Infected Pig Lungs. Inflammation. 2018;41:1104-1114 pubmed publisher
Baldauf M, Orth M, Dallmayer M, Marchetto A, Gerke J, Rubio R, et al. Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets. Oncotarget. 2018;9:1587-1601 pubmed publisher
He G, Lin X, Wang Y, Chen C. Dexmedetomidine impairs P?glycoprotein?mediated efflux function in L02 cells via the adenosine 5'?monophosphate?activated protein kinase/nuclear factor??B pathway. Mol Med Rep. 2018;17:5049-5056 pubmed publisher
Hu Q, Qin Y, Zhang B, Liang C, Ji S, Shi S, et al. FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1. Oncol Rep. 2017;38:2069-2077 pubmed publisher
Ye J, Wei X, Shang Y, Pan Q, Yang M, Tian Y, et al. Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity. Oncogene. 2017;36:6391-6407 pubmed publisher
Li J, Yang Y, Li L, Zhang L, Liu Q, Liu K, et al. Succinate accumulation impairs cardiac pyruvate dehydrogenase activity through GRP91-dependent and independent signaling pathways: Therapeutic effects of ginsenoside Rb1. Biochim Biophys Acta Mol Basis Dis. 2017;1863:2835-2847 pubmed publisher
Zhou W, Yao J, Wang G, Chen Z, Li Z, Feng D, et al. PKCζ phosphorylates TRAF2 to protect against intestinal ischemia-reperfusion-induced injury. Cell Death Dis. 2017;8:e2935 pubmed publisher
Yan X, Xun M, Dou X, Wu L, Han Y, Zheng J. Regulation of Na+-K+-ATPase effected high glucose-induced myocardial cell injury through c-Src dependent NADPH oxidase/ROS pathway. Exp Cell Res. 2017;357:243-251 pubmed publisher
Wen Y, Fu P, Wu K, Si K, Xie Y, Dan W, et al. Inhibition of Calcineurin A by FK506 Suppresses Seizures and Reduces the Expression of GluN2B in Membrane Fraction. Neurochem Res. 2017;42:2154-2166 pubmed publisher
Yan X, Xun M, Dou X, Wu L, Zhang F, Zheng J. Activation of Na+-K+-ATPase with DRm217 attenuates oxidative stress-induced myocardial cell injury via closing Na+-K+-ATPase/Src/Ros amplifier. Apoptosis. 2017;22:531-543 pubmed publisher
Manna P, Achari A, Jain S. Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1/AMPK/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice. Arch Biochem Biophys. 2017;615:22-34 pubmed publisher
Yan X, Xun M, Li J, Wu L, Dou X, Zheng J. Activation of Na+/K+-ATPase attenuates high glucose-induced H9c2 cell apoptosis via suppressing ROS accumulation and MAPKs activities by DRm217. Acta Biochim Biophys Sin (Shanghai). 2016;48:883-893 pubmed
Xiong Q, Cao Q, Zhou Q, Xie J, Shen Y, Wan R, et al. Arrhythmogenic cardiomyopathy in a patient with a rare loss-of-function KCNQ1 mutation. J Am Heart Assoc. 2015;4:e001526 pubmed publisher
product information
CatalogNo :
14418-1-AP
AntigenName :
ATP1A1
Package :
150UL
Price :
99 USD
FullName :
ATPase, Na+/K+ transporting, alpha 1 polypeptide
Immunogen :
Recombinant Protein
Species :
human, mouse, pig, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ATP1A1, Na(+)/K(+) ATPase 1, Na(+)/K(+) ATPase alpha 1 subunit, Na+/K+ ATPase 1, Sodium potassium ATPase alpha 1 polypeptide, Sodium pump subunit alpha 1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC050359
Category :
Binding Proteins;Disease Related;Membrane Proteins;Metabolism;Neurology;Plasma/Serum;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:200 ; IP 1:300 ; WB 1:10000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.