CNOT1 | Proteintech Group 14276-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

CNOT1

catalog :

14276-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation

citations: 27

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 3c	Yamaji M, Jishage M, Meyer C, Suryawanshi H, Der E, Yamaji M, et al. DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs. Nature. 2017;543:568-572 pubmed publisher
western blot; human; fig s3	Geissler R, Simkin A, Floss D, Patel R, Fogarty E, Scheller J, et al. A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1. Genes Dev. 2016;30:1070-85 pubmed publisher
	Mostafa D, Takahashi A, Yanagiya A, Yamaguchi T, Abe T, Kureha T, et al. Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability. RNA Biol. 2020;17:403-416 pubmed publisher
	Tavernier S, Athanasopoulos V, Verloo P, Behrens G, Staal J, Bogaert D, et al. A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation. Nat Commun. 2019;10:4779 pubmed publisher
	Park J, Seo J, Ahn N, Park S, Hwang J, Nam J. UPF1/SMG7-dependent microRNA-mediated gene regulation. Nat Commun. 2019;10:4181 pubmed publisher
	Park O, Ha H, Lee Y, Boo S, Kwon D, Song H, et al. Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex. Mol Cell. 2019;74:494-507.e8 pubmed publisher
	Nishimura T, Fakim H, Brandmann T, Youn J, Gingras A, Jinek M, et al. Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs. Nucleic Acids Res. 2018;46:12008-12021 pubmed publisher
	Chalabi Hagkarim N, Ryan E, Byrd P, Hollingworth R, Shimwell N, Agathanggelou A, et al. Degradation of a Novel DNA Damage Response Protein, Tankyrase 1 Binding Protein 1, following Adenovirus Infection. J Virol. 2018;92: pubmed publisher
	Jafarnejad S, Chapat C, Matta Camacho E, Gelbart I, Hesketh G, Arguello M, et al. Translational control of ERK signaling through miRNA/4EHP-directed silencing. elife. 2018;7: pubmed publisher
	Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein J, et al. Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA. Nat Commun. 2018;9:299 pubmed publisher
	Kim H, Ha Thi H, Hong S. IMP2 and IMP3 cooperate to promote the metastasis of triple-negative breast cancer through destabilization of progesterone receptor. Cancer Lett. 2018;415:30-39 pubmed publisher
	Hicks J, Li L, Matsui M, Chu Y, Volkov O, Johnson K, et al. Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription. Cell Rep. 2017;20:1543-1552 pubmed publisher
	Chapat C, Chettab K, Simonet P, Wang P, de la Grange P, Le Romancer M, et al. Alternative splicing of CNOT7 diversifies CCR4-NOT functions. Nucleic Acids Res. 2017;45:8508-8523 pubmed publisher
	Simsek D, Tiu G, Flynn R, Byeon G, Leppek K, Xu A, et al. The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell. 2017;169:1051-1065.e18 pubmed publisher
	Chapat C, Jafarnejad S, Matta Camacho E, Hesketh G, Gelbart I, Attig J, et al. Cap-binding protein 4EHP effects translation silencing by microRNAs. Proc Natl Acad Sci U S A. 2017;114:5425-5430 pubmed publisher
	Suzawa M, Noguchi K, Nishi K, Kozuka Hata H, Oyama M, Ui Tei K. Comprehensive Identification of Nuclear and Cytoplasmic TNRC6A-Associating Proteins. J Mol Biol. 2017;429:3319-3333 pubmed publisher
	Cheng D, Li J, Li S, Yang Q, Fan C. CNOT1 cooperates with LMNA to aggravate osteosarcoma tumorigenesis through the Hedgehog signaling pathway. Mol Oncol. 2017;11:388-404 pubmed publisher
	Cejas P, Cavazza A, Yandava C, Moreno V, Horst D, Moreno Rubio J, et al. Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype. Cancer Res. 2017;77:766-779 pubmed publisher
	Zheng X, Yang P, Lackford B, Bennett B, Wang L, Li H, et al. CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State. Stem Cell Reports. 2016;7:897-910 pubmed publisher
	Rataj F, Planel S, Desroches Castan A, Le Douce J, Lamribet K, Denis J, et al. The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1. Mol Biol Cell. 2016;27:3841-3854 pubmed
	Du H, Zhao Y, He J, Zhang Y, Xi H, Liu M, et al. YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex. Nat Commun. 2016;7:12626 pubmed publisher
	Mishima Y, Tomari Y. Codon Usage and 3' UTR Length Determine Maternal mRNA Stability in Zebrafish. Mol Cell. 2016;61:874-85 pubmed publisher
	Faraji F, Hu Y, Yang H, Lee M, Winkler G, Hafner M, et al. Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7. PLoS Genet. 2016;12:e1005820 pubmed publisher
	Fu R, Olsen M, Webb K, Bennett E, Lykke Andersen J. Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements. RNA. 2016;22:373-82 pubmed publisher
	Cano F, Rapiteanu R, Sebastiaan Winkler G, Lehner P. A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C. Nat Commun. 2015;6:8670 pubmed publisher
	Suzuki T, Kikuguchi C, Sharma S, Sasaki T, Tokumasu M, Adachi S, et al. CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins. Sci Rep. 2015;5:14779 pubmed publisher
	Nishimura T, Padamsi Z, Fakim H, Milette S, Dunham W, Gingras A, et al. The eIF4E-Binding Protein 4E-T Is a Component of the mRNA Decay Machinery that Bridges the 5' and 3' Termini of Target mRNAs. Cell Rep. 2015;11:1425-36 pubmed publisher

product information

CatalogNo :

14276-1-AP

AntigenName :

CNOT1

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

CCR4-NOT transcription complex, subunit 1

Immunogen :

Recombinant Protein

Species :

human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, CoIP, chIP, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

AD 005, CCR4 associated factor 1, CDC39, CNOT1, hNOT1, KIAA1007, NOT1, NOT1H

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC040523

Category :

Metabolism;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

IHC 1:200 ; IP 1:500 ; WB 1:800 ;