This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SRX1
catalog :
14273-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 14
Reference
Chawsheen H, Jiang H, Ying Q, Ding N, Thapa P, Wei Q. The redox regulator sulfiredoxin forms a complex with thioredoxin domain-containing 5 protein in response to ER stress in lung cancer cells. J Biol Chem. 2019;294:8991-9006 pubmed publisher
Harlan B, Pehar M, Killoy K, Vargas M. Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1. FASEB J. 2019;33:7084-7091 pubmed publisher
Romanello K, Teixeira K, Silva J, Nagamatsu S, Bezerra M, Domingos I, et al. Global analysis of erythroid cells redox status reveals the involvement of Prdx1 and Prdx2 in the severity of beta thalassemia. PLoS ONE. 2018;13:e0208316 pubmed publisher
Olthoff J, Lindsay A, Abo Zahrah R, Baltgalvis K, Patrinostro X, Belanto J, et al. Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle. Nat Commun. 2018;9:5104 pubmed publisher
Mishra M, Jiang H, Chawsheen H, Gerard M, Toledano M, Wei Q. Nrf2-activated expression of sulfiredoxin contributes to urethane-induced lung tumorigenesis. Cancer Lett. 2018;432:216-226 pubmed publisher
Schultz M, Diaz A, Smite S, Lay A, DeCant B, McKinney R, et al. Thioredoxin system-mediated regulation of mutant Kras associated pancreatic neoplasia and cancer. Oncotarget. 2017;8:92667-92681 pubmed publisher
Choi E, Jung B, Lee S, Yoo H, Shin E, Ko H, et al. A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Oncogene. 2017;36:5285-5295 pubmed publisher
Lan K, Zhao Y, Fan Y, Ma B, Yang S, Liu Q, et al. Sulfiredoxin May Promote Cervical Cancer Metastasis via Wnt/?-Catenin Signaling Pathway. Int J Mol Sci. 2017;18: pubmed publisher
Chen X, Lan K, Liu Q, Yang X, Wang H. Sulfiredoxin may promote metastasis and invasion of cervical squamous cell carcinoma by epithelial-mesenchymal transition. Tumour Biol. 2017;39:1010428317695942 pubmed publisher
Pireaux V, Sauvage A, Bihin B, Van Steenbrugge M, Rousseau A, Van Antwerpen P, et al. Myeloperoxidase-Oxidized LDLs Enhance an Anti-Inflammatory M2 and Antioxidant Phenotype in Murine Macrophages. Mediators Inflamm. 2016;2016:8249476 pubmed
Starheim K, Holien T, Misund K, Johansson I, Baranowska K, Sponaas A, et al. Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells. Blood Cancer J. 2016;6:e446 pubmed publisher
Jiang H, Wu L, Chen J, Mishra M, Chawsheen H, Zhu H, et al. Sulfiredoxin Promotes Colorectal Cancer Cell Invasion and Metastasis through a Novel Mechanism of Enhancing EGFR Signaling. Mol Cancer Res. 2015;13:1554-66 pubmed publisher
Hintsala H, Soini Y, Haapasaari K, Karihtala P. Dysregulation of redox-state-regulating enzymes in melanocytic skin tumours and the surrounding microenvironment. Histopathology. 2015;67:348-57 pubmed publisher
Yu S, Wang X, Lei S, Chen X, Liu Y, Zhou Y, et al. Sulfiredoxin-1 protects primary cultured astrocytes from ischemia-induced damage. Neurochem Int. 2015;82:19-27 pubmed publisher
product information
CatalogNo :
14273-1-AP
AntigenName :
SRX1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
sulfiredoxin 1 homolog (S. cerevisiae)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
C20orf139, SRX, SRX1, SRXN1, Sulfiredoxin 1, YKL086W
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC047707
Category :
Binding Proteins;Immunology;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:50 ; IP 1:400 ; WB 1:400 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.