This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
GFPT1
catalog :
14132-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 10
Reference
Sharma N, Gupta V, Garrido V, Hadad R, Durden B, Kesh K, et al. Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy. J Clin Invest. 2020;130:451-465 pubmed publisher
Qin L, Wang J, Zhao R, Zhang X, Mei Y. Ginsenoside-Rb1 Improved Diabetic Cardiomyopathy through Regulating Calcium Signaling by Alleviating Protein O-GlcNAcylation. J Agric Food Chem. 2019;67:14074-14085 pubmed publisher
Paredes F, Williams H, Quintana R, San Martin A. Mitochondrial Protein Poldip2 Controls VSMC Differentiated Phenotype by O-Linked GlcNAc Transferase-Dependent Inhibition of a Ubiquitin Proteasome System. Circ Res. 2019;: pubmed publisher
Dai W, Dierschke S, Toro A, Dennis M. Consumption of a high fat diet promotes protein O-GlcNAcylation in mouse retina via NR4A1-dependent GFAT2 expression. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3568-3576 pubmed publisher
Issop Y, Hathazi D, Khan M, Rudolf R, Weis J, Spendiff S, et al. GFPT1 deficiency in muscle leads to myasthenia and myopathy in mice. Hum Mol Genet. 2018;27:3218-3232 pubmed publisher
Shtraizent N, DeRossi C, Nayar S, Sachidanandam R, Katz L, Prince A, et al. MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect. elife. 2017;6: pubmed publisher
Hugo S, Schlegel A. A Genetic Model to Study Increased Hexosamine Biosynthetic Flux. Endocrinology. 2017;158:2420-2426 pubmed publisher
Oikari S, Makkonen K, Deen A, Tyni I, Kärnä R, Tammi R, et al. Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis. Glycobiology. 2016;26:710-22 pubmed publisher
Dusl M, Senderek J, Müller J, Vogel J, Pertl A, Stucka R, et al. A 3'-UTR mutation creates a microRNA target site in the GFPT1 gene of patients with congenital myasthenic syndrome. Hum Mol Genet. 2015;24:3418-26 pubmed publisher
Ganguly R, Sahu S, Chavez R, Raman P. Trivalent chromium inhibits TSP-1 expression, proliferation, and O-GlcNAc signaling in vascular smooth muscle cells in response to high glucose in vitro. Am J Physiol Cell Physiol. 2015;308:C111-22 pubmed publisher
product information
CatalogNo :
14132-1-AP
AntigenName :
GFPT1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
glutamine-fructose-6-phosphate transaminase 1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
GFA, GFAT, GFAT 1, GFAT1, GFAT1m, GFPT, GFPT1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC045641
Category :
Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:200 ; WB 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.