This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SOCS3
catalog :
14025-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 23
Reference
Yuan C, Yang D, Ma J, Yang J, Xue J, Song F, et al. Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells. Braz J Med Biol Res. 2020;53:e9488 pubmed publisher
Meng C, Qi H, Wang X, Wu X, Huang W, Wang H, et al. Expression and methylation levels of suppressor of cytokine signaling 3 in rheumatic arthritis synovial fibroblasts. Exp Mol Pathol. 2019;113:104361 pubmed publisher
Cai B, Lu Y, Xu M. Acid sphingomyelinase downregulation alleviates vascular endothelial leptin resistance in rats. Acta Pharmacol Sin. 2019;: pubmed publisher
Wang J, Gao W, Deng S, Liu X, Jia H, Ma W. High temperature suppressed SSC self-renewal through S phase cell cycle arrest but not apoptosis. Stem Cell Res Ther. 2019;10:227 pubmed publisher
Wang D, Xu B, Wang J, Wang H, Guo J, Ji H, et al. Response of the maternal hypothalamus to cold stress during late pregnancy in rats. Brain Res. 2019;1722:146354 pubmed publisher
Zhu Y, Meng Y, Zhao Y, Zhu J, Xu H, Zhang E, et al. Toxicological exploration of peptide-based cationic liposomes in siRNA delivery. Colloids Surf B Biointerfaces. 2019;179:66-76 pubmed publisher
Wang J, Teng Y, Zhao G, Li F, Hou A, Sun B, et al. Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection. Int J Mol Sci. 2019;20: pubmed publisher
Wu M, Sheng L, Cheng M, Zhang H, Jiang Y, Lin S, et al. Low doses of decitabine improve the chemotherapy efficacy against basal-like bladder cancer by targeting cancer stem cells. Oncogene. 2019;: pubmed publisher
Wu R, Liu Y, Zhao Y, Bi Z, Yao Y, Liu Q, et al. m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner. Cell Death Dis. 2019;10:171 pubmed publisher
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P. Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats. Gene. 2019;697:11-18 pubmed publisher
Zhao G, Gong L, Su D, Jin Y, Guo C, Yue M, et al. Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin β1. J Clin Invest. 2019;129:972-987 pubmed publisher
Sun W, Xiao B, Jia A, Qiu L, Zeng Q, Liu D, et al. MBD2-mediated Th17 differentiation in severe asthma is associated with impaired SOCS3 expression. Exp Cell Res. 2018;371:196-204 pubmed publisher
Argente Arizón P, Castro González D, Díaz F, Fernández Gómez M, Sánchez Garrido M, Tena Sempere M, et al. Neonatal Overnutrition Increases Testicular Size and Expression of Luteinizing Hormone β-Subunit in Peripubertal Male Rats. Front Endocrinol (Lausanne). 2018;9:168 pubmed publisher
Lian S, Wang D, Xu B, Guo W, Wang L, Li W, et al. Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats. Behav Brain Res. 2018;346:1-10 pubmed publisher
Xu J, Zhou L, Wang S, Zhu J, Liu T, Jia Y, et al. Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats. Environ Sci Pollut Res Int. 2018;25:3596-3607 pubmed publisher
Argente Arizón P, Díaz F, Ros P, Barrios V, Tena Sempere M, García Segura L, et al. The Hypothalamic Inflammatory/Gliosis Response to Neonatal Overnutrition Is Sex and Age Dependent. Endocrinology. 2018;159:368-387 pubmed publisher
Igbe I, Shen X, Jiao W, Qiang Z, Deng T, Li S, et al. Dietary quercetin potentiates the antiproliferative effect of interferon-? in hepatocellular carcinoma cells through activation of JAK/STAT pathway signaling by inhibition of SHP2 phosphatase. Oncotarget. 2017;8:113734-113748 pubmed publisher
Wonganan O, He Y, Shen X, Wongkrajang K, Suksamrarn A, Zhang G, et al. 6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon ?/? by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells. Toxicol Appl Pharmacol. 2017;336:31-39 pubmed publisher
Elkaim R, Bugueno Valdebenito I, Benkirane Jessel N, Tenenbaum H. Porphyromonas gingivalis and its lipopolysaccharide differently modulate epidermal growth factor-dependent signaling in human gingival epithelial cells. J Oral Microbiol. 2017;9:1334503 pubmed publisher
Fang L, Hodge J, Saaoud F, Wang J, Iwanowycz S, Wang Y, et al. Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment. Oncoimmunology. 2017;6:e1312042 pubmed publisher
Lin X, Qin Y, Jia J, Lin T, Lin X, Chen L, et al. MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice. PLoS Genet. 2016;12:e1006308 pubmed publisher
Yan C, Liu Y, Gao H, Wang X. Suppressors of cytokine signaling 3 is essential for FcγR-mediated inflammatory response via enhancing CCAAT/enhancer-binding protein δ transcriptional activity in macrophages. Exp Cell Res. 2015;337:120-7 pubmed publisher
Dong Z, Lu X, Yang Y, Zhang T, Li Y, Chai Y, et al. IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation. BMC Pulm Med. 2015;15:13 pubmed publisher
product information
CatalogNo :
14025-1-AP
AntigenName :
SOCS3
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
suppressor of cytokine signaling 3
Immunogen :
Recombinant Protein
Species :
chicken, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ATOD4, CIS 3, CIS3, Cish3, SOCS 3, SOCS3, SSI 3, SSI3, STAT induced STAT inhibitor 3
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC060858
Category :
Apoptosis;Binding Proteins;Development;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:200 ; IP 1:500 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.