| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; loading ...; fig 4b
| Boukhalfa A, Nascimbeni A, Ramel D, Dupont N, Hirsch E, Gayral S, et al. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nat Commun. 2020;11:294 pubmed publisher |
- immunocytochemistry; mouse; 1:50; loading ...; fig s10a
- western blot; mouse; 1:1000; loading ...; fig s10e
| Martin Hurtado A, Martin Morales R, Robledinos Antón N, Blanco R, Palacios Blanco I, Lastres Becker I, et al. NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling. Sci Rep. 2019;9:13896 pubmed publisher |
- immunocytochemistry; mouse; 1:200; loading ...; fig 5
| Hua K, Ferland R. Fixation methods can differentially affect ciliary protein immunolabeling. Cilia. 2017;6:5 pubmed publisher |
- immunocytochemistry; human; loading ...; fig s1b
| Oliazadeh N, Gorman K, Eveleigh R, Bourque G, Moreau A. Identification of Elongated Primary Cilia with Impaired Mechanotransduction in Idiopathic Scoliosis Patients. Sci Rep. 2017;7:44260 pubmed publisher |
- immunocytochemistry; mouse; 1:300; loading ...; fig s5
- western blot; mouse; 1:800; loading ...; fig 6d
| Yu F, Sharma S, Skowronek A, Erdmann K. The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis. Sci Rep. 2016;6:35399 pubmed publisher |
- western blot; human; loading ...; fig 5C
- immunocytochemistry; mouse; fig 6F
| Hong C, Hamilton B. Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function. PLoS Genet. 2016;12:e1006357 pubmed publisher |
- immunocytochemistry; human; 1:200; loading ...; fig 3A
| Kim M, Froese C, Xie H, Trimble W. Immunofluorescent staining of septins in primary cilia. Methods Cell Biol. 2016;136:269-83 pubmed publisher |
- immunocytochemistry; dogs; 1:100; loading ...; fig s1f
| Bernabé Rubio M, Andrés G, Casares Arias J, Fernández Barrera J, Rangel L, Reglero Real N, et al. Novel role for the midbody in primary ciliogenesis by polarized epithelial cells. J Cell Biol. 2016;214:259-73 pubmed publisher |
- immunocytochemistry; human; fig 2
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- western blot; human; fig 5c
| Kim J, Ki S, Joung J, Scott E, Heynen Genel S, Aza Blanc P, et al. Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation. Biochim Biophys Acta. 2016;1863:1307-18 pubmed publisher |
- immunocytochemistry; mouse; 1:200; loading ...; fig 6h
- western blot; mouse; 1:1000; loading ...; fig 6f
| Katoh Y, Terada M, Nishijima Y, Takei R, Nozaki S, Hamada H, et al. Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex. J Biol Chem. 2016;291:10962-75 pubmed publisher |
- immunocytochemistry; human; 1:500; loading ...; fig 5b
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| Chen S, Qin L, Wu X, Fu X, Lin S, Chen D, et al. Moderate Fluid Shear Stress Regulates Heme Oxygenase-1 Expression to Promote Autophagy and ECM Homeostasis in the Nucleus Pulposus Cells. Front Cell Dev Biol. 2020;8:127 pubmed publisher |
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| Vuolo L, Stevenson N, Heesom K, Stephens D. Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function. elife. 2018;7: pubmed publisher |
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| Shamoto N, Narita K, Kubo T, Oda T, Takeda S. CFAP70 Is a Novel Axoneme-Binding Protein That Localizes at the Base of the Outer Dynein Arm and Regulates Ciliary Motility. Cells. 2018;7: pubmed publisher |
| Abdelhamed Z, Ryan T, Fuller M, Coulson Gilmer C, Abdelmottaleb D, Wang T, et al. Characterization of Primary Cilia in Normal Fallopian Tube Epithelium and Serous Tubal Intraepithelial Carcinoma. Int J Gynecol Cancer. 2018;28:1535-1544 pubmed publisher |
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| Chekuri A, Guru A, Biswas P, Branham K, Borooah S, Soto Hermida A, et al. IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis. Hum Genet. 2018;137:447-458 pubmed publisher |
| Dafinger C, Rinschen M, Borgal L, Ehrenberg C, Basten S, Franke M, et al. Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus. Exp Mol Med. 2018;50:75 pubmed publisher |
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| Funabashi T, Katoh Y, Okazaki M, Sugawa M, Nakayama K. Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis. J Cell Biol. 2018;217:2867-2876 pubmed publisher |
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| Barny I, Perrault I, Michel C, Soussan M, Goudin N, Rio M, et al. Basal exon skipping and nonsense-associated altered splicing allows bypassing complete CEP290 loss-of-function in individuals with unusually mild retinal disease. Hum Mol Genet. 2018;: pubmed publisher |
| Lee J, Yi S, Won M, Song Y, Yi H, Park Y, et al. Loss-of-function of IFT88 determines metabolic phenotypes in thyroid cancer. Oncogene. 2018;37:4455-4474 pubmed publisher |
| Forbes T, Howden S, Lawlor K, Phipson B, Maksimovic J, Hale L, et al. Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms. Am J Hum Genet. 2018;102:816-831 pubmed publisher |
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| Revenkova E, Liu Q, Gusella G, Iomini C. The Joubert syndrome protein ARL13B binds tubulin to maintain uniform distribution of proteins along the ciliary membrane. J Cell Sci. 2018;131: pubmed publisher |
| Silva L, Jacobs D, Allard B, Fields T, Sharma M, Wallace D, et al. Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells. Sci Rep. 2018;8:4985 pubmed publisher |
| Vion A, Alt S, Klaus Bergmann A, Szymborska A, Zheng T, Perovic T, et al. Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression. J Cell Biol. 2018;217:1651-1665 pubmed publisher |
| Ogungbenro Y, Tena T, Gaboriau D, Lalor P, Dockery P, Philipp M, et al. Centrobin controls primary ciliogenesis in vertebrates. J Cell Biol. 2018;217:1205-1215 pubmed publisher |
| Khan N, Garg A, Agostinis P, Swinnen J. Drug-induced ciliogenesis in pancreatic cancer cells is facilitated by the secreted ATP-purinergic receptor signaling pathway. Oncotarget. 2018;9:3507-3518 pubmed publisher |
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| Schmid F, Schou K, Vilhelm M, Holm M, Breslin L, Farinelli P, et al. IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases. J Cell Biol. 2018;217:151-161 pubmed publisher |
| Deng Y, Cai Z, Shi S, Jiang H, Shang Y, Ma N, et al. Cilia loss sensitizes cells to transformation by activating the mevalonate pathway. J Exp Med. 2018;215:177-195 pubmed publisher |
| Hartill V, van de Hoek G, Patel M, Little R, Watson C, Berry I, et al. DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport. Hum Mol Genet. 2018;27:529-545 pubmed publisher |
| Takahashi K, Nagai T, Chiba S, Nakayama K, Mizuno K. Glucose deprivation induces primary cilium formation through mTORC1 inactivation. J Cell Sci. 2018;131: pubmed publisher |
| Lee S, Joo K, Jung E, Hong H, Seo J, Kim J. Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1. FASEB J. 2018;32:957-968 pubmed publisher |
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| Kasioulis I, Das R, Storey K. Inter-dependent apical microtubule and actin dynamics orchestrate centrosome retention and neuronal delamination. elife. 2017;6: pubmed publisher |
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| Hu L, Wang B, Zhang Y. Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer's disease by regulating cilia function. Alzheimers Res Ther. 2017;9:76 pubmed publisher |
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| Shimada H, Lu Q, Insinna Kettenhofen C, Nagashima K, English M, Semler E, et al. In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations. Cell Rep. 2017;20:384-396 pubmed publisher |
| Kanie T, Abbott K, Mooney N, Plowey E, Demeter J, JACKSON P. The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Dev Cell. 2017;42:22-36.e12 pubmed publisher |
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| Das A, Qian J, Tsang W. USP9X counteracts differential ubiquitination of NPHP5 by MARCH7 and BBS11 to regulate ciliogenesis. PLoS Genet. 2017;13:e1006791 pubmed publisher |
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| Ernandez T, Komarynets O, Chassot A, Sougoumarin S, Soulie P, Wang Y, et al. Primary cilia control the maturation of tubular lumen in renal collecting duct epithelium. Am J Physiol Cell Physiol. 2017;313:C94-C107 pubmed publisher |
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| Goetz S, Bangs F, Barrington C, Katsanis N, Anderson K. The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling. PLoS ONE. 2017;12:e0173399 pubmed publisher |
| Xin D, Christopher K, Zeng L, Kong Y, Weatherbee S. IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture. Development. 2017;144:1544-1553 pubmed publisher |
| Yeyati P, Schiller R, Mali G, Kasioulis I, Kawamura A, Adams I, et al. KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability. J Cell Biol. 2017;216:999-1013 pubmed publisher |
| Katoh Y, Michisaka S, Nozaki S, Funabashi T, Hirano T, Takei R, et al. Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system. Mol Biol Cell. 2017;28:898-906 pubmed publisher |
| Schou K, Mogensen J, Morthorst S, Nielsen B, Aleliunaite A, Serra Marques A, et al. KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling. Nat Commun. 2017;8:14177 pubmed publisher |
| Phua S, Chiba S, Suzuki M, Su E, Roberson E, Pusapati G, et al. Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2017;168:264-279.e15 pubmed publisher |
| Funabashi T, Katoh Y, Michisaka S, Terada M, Sugawa M, Nakayama K. Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. Mol Biol Cell. 2017;28:624-633 pubmed publisher |
| Kobayashi T, Nakazono K, Tokuda M, Mashima Y, Dynlacht B, Itoh H. HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma. EMBO Rep. 2017;18:334-343 pubmed publisher |
| Nozaki S, Katoh Y, Terada M, Michisaka S, Funabashi T, Takahashi S, et al. Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E. J Cell Sci. 2017;130:563-576 pubmed publisher |
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| Wang C, Tsai H, Syu J, Chen T, Su M. Primary Cilium-Regulated EG-VEGF Signaling Facilitates Trophoblast Invasion. J Cell Physiol. 2017;232:1467-1477 pubmed publisher |
| Durán I, Taylor S, Zhang W, Martin J, Forlenza K, Spiro R, et al. Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome. Sci Rep. 2016;6:34232 pubmed publisher |
| Nechipurenko I, Olivier Mason A, Kazatskaya A, Kennedy J, McLachlan I, Heiman M, et al. A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis. Dev Cell. 2016;38:493-506 pubmed publisher |
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