MFN1 | Proteintech Group 13798-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

MFN1

catalog :

13798-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

citations: 31

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig s4c	Chung K, Hsu C, Fan L, Huang Z, Bhatia D, Chen Y, et al. Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis. Nat Commun. 2019;10:3390 pubmed publisher
western blot; mouse; fig 4	Sharoar M, Shi Q, Ge Y, He W, Hu X, Perry G, et al. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016;21:1263-71 pubmed publisher
	Ma D, Zheng B, Liu H, Zhao Y, Liu X, Zhang X, et al. Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission. PLoS Biol. 2020;18:e3000808 pubmed publisher
	Hu Y, Chen H, Zhang L, Lin X, Li X, Zhuang H, et al. The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses. Autophagy. 2020;:1-15 pubmed publisher
	Deng X, Liu J, Liu L, Sun X, Huang J, Dong J. Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway. Int J Biol Sci. 2020;16:1403-1416 pubmed publisher
	Tokuyama T, Hirai A, Shiiba I, Ito N, Matsuno K, Takeda K, et al. Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients. Biomolecules. 2020;10: pubmed publisher
	Gao P, Yang M, Chen X, Xiong S, Liu J, Sun L. DsbA-L deficiency exacerbates mitochondrial dysfunction of tubular cells in diabetic kidney disease. Clin Sci (Lond). 2020;134:677-694 pubmed publisher
	Klimova N, Fearnow A, Long A, Kristian T. NAD+ precursor modulates post-ischemic mitochondrial fragmentation and reactive oxygen species generation via SIRT3 dependent mechanisms. Exp Neurol. 2020;325:113144 pubmed publisher
	Wang H, Zhu S, Liu J, Miao C, Zhang Y, Zhou B. Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice. Chemosphere. 2020;238:124607 pubmed publisher
	Wang H, Liu J, Wei S, Zhao W, Zhu S, Zhou B. Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice. Chemosphere. 2019;241:125099 pubmed publisher
	Wu W, Zhao D, Shah S, Zhang X, Lai M, Yang D, et al. OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases. Cell Death Dis. 2019;10:710 pubmed publisher
	Yuan J, Chen C, Cui J, Lu J, Yan C, Wei X, et al. Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae. Cell Metab. 2019;30:675-688.e7 pubmed publisher
	Kim J, Park H, Choi S, Kong M, Kang T. CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1. Cells. 2019;8: pubmed publisher
	Zhou Y, Carmona S, Muhammad A, Bell S, Landeros J, Vazquez M, et al. Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model. J Clin Invest. 2019;130:1756-1771 pubmed publisher
	Zhao L, Zhuang J, Wang Y, Zhou D, Zhao D, Zhu S, et al. Propofol Ameliorates H9c2 Cells Apoptosis Induced by Oxygen Glucose Deprivation and Reperfusion Injury via Inhibiting High Levels of Mitochondrial Fusion and Fission. Front Pharmacol. 2019;10:61 pubmed publisher
	Klimova N, Long A, Kristian T. Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice. J Neurosci Res. 2019;97:975-990 pubmed publisher
	Zhong X, Cui P, Cai Y, Wang L, He X, Long P, et al. Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells. Cell Metab. 2019;29:979-992.e4 pubmed publisher
	Li S, Zhao H, Wang Y, Shao Y, Liu J, Xing M. Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens. Poult Sci. 2019;98:734-744 pubmed publisher
	Reddy P, Yin X, Manczak M, Kumar S, Pradeepkiran J, Vijayan M, et al. Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease. Hum Mol Genet. 2018;27:2502-2516 pubmed publisher
	Dun Y, Liu S, Zhang W, Xie M, Qiu L. Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control. Oxid Med Cell Longev. 2017;2017:8024857 pubmed publisher
	Du J, Zhang X, Han J, Man K, Zhang Y, Chu E, et al. Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis. Theranostics. 2017;7:4192-4203 pubmed publisher
	Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, et al. The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart. Chemosphere. 2017;189:489-497 pubmed publisher
	Xu Z, Jin X, Pan T, Liu T, Wan N, Li S. Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens. Oncotarget. 2017;8:52629-52641 pubmed publisher
	Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, et al. Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission. EMBO J. 2017;36:1330-1347 pubmed publisher
	Lu Y, Wang R, Dong Y, Tucker D, Zhao N, Ahmed M, et al. Low-level laser therapy for beta amyloid toxicity in rat hippocampus. Neurobiol Aging. 2017;49:165-182 pubmed publisher
	Manczak M, Kandimalla R, Fry D, Sesaki H, Reddy P. Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease. Hum Mol Genet. 2016;25:5148-5166 pubmed publisher
	Kim D, Lee K, Gabr A, Choi G, Kim J, Ko S, et al. A?-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis. Biochim Biophys Acta. 2016;1863:2820-2834 pubmed publisher
	Li S, Wang J, Zhou A, Khan F, Hu L, Zhang S. Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis. Oncotarget. 2016;7:56002-56012 pubmed publisher
	Zhang C, Shi Z, Zhang L, Zhou Z, Zheng X, Liu G, et al. Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology. J Cell Sci. 2016;129:994-1002 pubmed publisher
	Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, et al. Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization. Cell Death Differ. 2016;23:380-92 pubmed publisher
	Leduc Gaudet J, Picard M, St Jean Pelletier F, Sgarioto N, Auger M, VallÃ©e J, et al. Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice. Oncotarget. 2015;6:17923-37 pubmed

product information

CatalogNo :

13798-1-AP

AntigenName :

MFN1

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

mitofusin 1

Immunogen :

Recombinant Protein

Species :

chicken, human, monkey, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IHC, IF, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC040557

Category :

Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Membrane Proteins;Metabolism;Neurology;Transport/Trafficking;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

IHC 1:200 ; WB 1:600 ;