This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
MX1
catalog :
13750-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 35
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, et al. Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS Pathog. 2019;15:e1008002 pubmed publisher
  • western blot; human; loading ...; fig 3a
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, et al. NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1. J Immunol. 2019;: pubmed publisher
  • western blot; human; loading ...; fig 3e
Xia Z, Xu G, Yang X, Peng N, Zuo Q, Zhu S, et al. Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex. J Immunol. 2017;198:3690-3704 pubmed publisher
Min Y, Ning Y, Wang H, Deng F. A RIG-I-like receptor directs antiviral responses to a bunyavirus and is antagonized by virus-induced blockade of TRIM25-mediated ubiquitination. J Biol Chem. 2020;295:9691-9711 pubmed publisher
Holthaus D, Vasou A, Bamford C, Andrejeva J, Paulus C, Randall R, et al. Direct Antiviral Activity of IFN-Stimulated Genes Is Responsible for Resistance to Paramyxoviruses in ISG15-Deficient Cells. J Immunol. 2020;205:261-271 pubmed publisher
Benninghoff A, Bates M, Chauhan P, Wierenga K, Gilley K, Holian A, et al. Docosahexaenoic Acid Consumption Impedes Early Interferon- and Chemokine-Related Gene Expression While Suppressing Silica-Triggered Flaring of Murine Lupus. Front Immunol. 2019;10:2851 pubmed publisher
Wang G, Jiang L, Wang J, Zhang J, Kong F, Li Q, et al. The G protein-coupled receptor FFAR2 promotes internalization during influenza A virus entry. J Virol. 2019;: pubmed publisher
Abdulhaqq S, Martinez M, Kang G, Rodriguez I, Nichols S, Beaumont D, et al. Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques. Nat Commun. 2019;10:3753 pubmed publisher
Li X, Guo G, Lu M, Chai W, Li Y, Tong X, et al. Long Noncoding RNA Lnc-MxA Inhibits Beta Interferon Transcription by Forming RNA-DNA Triplexes at Its Promoter. J Virol. 2019;93: pubmed publisher
McFarlane S, Orr A, Roberts A, Conn K, Iliev V, Loney C, et al. The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathog. 2019;15:e1007667 pubmed publisher
Wang Y, Zhao H, Liu J, Shao Y, Xing M. Molecular cloning and transcriptional regulation of Indian peafowl (Pavo cristatus) IFN-α gene. Cell Stress Chaperones. 2019;24:323-332 pubmed publisher
Yang K, Guan S, Zhang H, Chen Z. Induction of interleukin 6 impairs the anti-HBV efficiency of IFN-α in human hepatocytes through upregulation of SOCS3. J Med Virol. 2019;91:803-812 pubmed publisher
Ma H, Yang W, Zhang L, Liu S, Zhao M, Zhou G, et al. Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma. Br J Cancer. 2019;120:317-330 pubmed publisher
Li S, Wang Y, Zhao H, Shao Y, Liu J, Xing M. Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon-α: Knockdown p53 negatively modulates antiviral response. Dev Comp Immunol. 2019;90:29-40 pubmed publisher
Ringer K, Riehl J, Müller M, Dewes J, Hoff F, Jacob R. The large GTPase Mx1 binds Kif5B for cargo transport along microtubules. Traffic. 2018;19:947-964 pubmed publisher
He J, Liu H, Zhong J, Guo Z, Wu J, Zhang H, et al. Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury. Neurobiol Dis. 2018;117:114-124 pubmed publisher
Bodewes I, Huijser E, van Helden Meeuwsen C, Tas L, Huizinga R, Dalm V, et al. TBK1: A key regulator and potential treatment target for interferon positive Sjögren's syndrome, systemic lupus erythematosus and systemic sclerosis. J Autoimmun. 2018;91:97-102 pubmed publisher
Wang H, Xin X, Wang M, Han L, Li J, Hao Y, et al. Myxovirus resistance protein A inhibits hepatitis C virus replication through JAK-STAT pathway activation. Arch Virol. 2018;163:1429-1438 pubmed publisher
Luo W, Zhang J, Liang L, Wang G, Li Q, Zhu P, et al. Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication. PLoS Pathog. 2018;14:e1006851 pubmed publisher
Ma H, Jin S, Yang W, Zhou G, Zhao M, Fang S, et al. Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma. Br J Cancer. 2018;118:509-521 pubmed publisher
Wahadat M, Bodewes I, Maria N, van Helden Meeuwsen C, van Dijk Hummelman A, Steenwijk E, et al. Type I IFN signature in childhood-onset systemic lupus erythematosus: a conspiracy of DNA- and RNA-sensing receptors?. Arthritis Res Ther. 2018;20:4 pubmed publisher
Alandijany T, Roberts A, Conn K, Loney C, McFarlane S, Orr A, et al. Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection. PLoS Pathog. 2018;14:e1006769 pubmed publisher
Zhao H, Wang Y, Shao Y, Liu J, Li J, Zong H, et al. Characterization of Whooper Swan (Cygnus cygnus) Interferon ?: Prokaryotic Expression, Biological Activities, and Physicochemical Characteristics. J Interferon Cytokine Res. 2018;38:20-28 pubmed publisher
Wan Y, Cao W, Han T, Ren S, Feng J, Chen T, et al. Inducible Rubicon facilitates viral replication by antagonizing interferon production. Cell Mol Immunol. 2017;14:607-620 pubmed publisher
Chen J, Xu W, Chen Y, Xie X, Zhang Y, Ma C, et al. Matrix Metalloproteinase 9 Facilitates Hepatitis B Virus Replication through Binding with Type I Interferon (IFN) Receptor 1 To Repress IFN/JAK/STAT Signaling. J Virol. 2017;91: pubmed publisher
Li Z, Chen F, Ye S, Guo X, Muhanmmad Memon A, Wu M, et al. Comparative Proteome Analysis of Porcine Jejunum Tissues in Response to a Virulent Strain of Porcine Epidemic Diarrhea Virus and Its Attenuated Strain. Viruses. 2016;8: pubmed
Yang X, Hao H, Xia Z, Xu G, Cao Z, Chen X, et al. Soluble IL-6 Receptor and IL-27 Subunit p28 Protein Complex Mediate the Antiviral Response through the Type III IFN Pathway. J Immunol. 2016;197:2369-81 pubmed publisher
Bulli L, Apolonia L, Kutzner J, Pollpeter D, Goujon C, Herold N, et al. Complex Interplay between HIV-1 Capsid and MX2-Independent Alpha Interferon-Induced Antiviral Factors. J Virol. 2016;90:7469-7480 pubmed publisher
Maarifi G, Hannoun Z, Geoffroy M, El Asmi F, Zarrouk K, Nisole S, et al. MxA Mediates SUMO-Induced Resistance to Vesicular Stomatitis Virus. J Virol. 2016;90:6598-6610 pubmed publisher
Jackson J, Markert J, Li L, Carroll S, Cassady K. STAT1 and NF-κB Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells. Mol Cancer Res. 2016;14:482-92 pubmed publisher
Maria N, van Helden Meeuwsen C, Brkic Z, Paulissen S, Steenwijk E, Dalm V, et al. Association of Increased Treg Cell Levels With Elevated Indoleamine 2,3-Dioxygenase Activity and an Imbalanced Kynurenine Pathway in Interferon-Positive Primary Sjögren's Syndrome. Arthritis Rheumatol. 2016;68:1688-99 pubmed publisher
Bai L, Zhang W, Tan L, Yang H, Ge M, Zhu C, et al. Hepatitis B virus hijacks CTHRC1 to evade host immunity and maintain replication. J Mol Cell Biol. 2015;7:543-56 pubmed publisher
Liu S, Peng N, Xie J, Hao Q, Zhang M, Zhang Y, et al. Human hepatitis B virus surface and e antigens inhibit major vault protein signaling in interferon induction pathways. J Hepatol. 2015;62:1015-23 pubmed publisher
Brown S, Knowell A, Hunt A, Patel D, Bhosle S, Chaudhary J. Interferon inducible antiviral MxA is inversely associated with prostate cancer and regulates cell cycle, invasion and Docetaxel induced apoptosis. Prostate. 2015;75:266-79 pubmed publisher
Knight J, Subramanian V, O Dell A, Yalavarthi S, Zhao W, Smith C, et al. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Ann Rheum Dis. 2015;74:2199-206 pubmed publisher
product information
CatalogNo :
13750-1-AP
AntigenName :
MX1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
Myxovirus resistance protein 1
Immunogen :
Recombinant Protein
Species :
chicken, dog, human, indian peafowls, macaca mulata, monkey, mouse, pig
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
IFI 78K, IFI78, MX, MX1, MxA, Myxovirus resistance protein 1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC032602
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Signal transduction;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:0 ; WB 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.