Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; mouse; fig 2
- immunocytochemistry; mouse; 1:500; fig s5
| Noda K, Kitami M, Kitami K, Kaku M, Komatsu Y. Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development. Proc Natl Acad Sci U S A. 2016;113:E2589-97 pubmed publisher
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- western blot; human; 1:1500; loading ...; fig 10c
| Boukhalfa A, Nascimbeni A, Ramel D, Dupont N, Hirsch E, Gayral S, et al. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nat Commun. 2020;11:294 pubmed publisher
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- immunocytochemistry; human; 1:300; loading ...; fig s6b
- western blot; human; 1:1000; loading ...; fig s6c
| Stoetzel C, Bär S, De Craene J, Scheidecker S, Etard C, Chicher J, et al. A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi. Nat Commun. 2016;7:13586 pubmed publisher
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| Su S, Begum S, Ezratty E. An IFT20 mechano-trafficking axis is required for integrin recycling, focal adhesion dynamics and polarized cell migration. Mol Biol Cell. 2020;:mbcE20040232 pubmed publisher
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| Ran J, Liu M, Feng J, Li H, Ma H, Song T, et al. ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia. Dev Cell. 2020;53:287-299.e5 pubmed publisher
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| Fabbri L, Dufies M, Lacas Gervais S, Gardie B, Gad Lapiteau S, Parola J, et al. Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients. Theranostics. 2020;10:2696-2713 pubmed publisher
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| Iaconis D, Crina C, Brillante S, Indrieri A, Morleo M, Franco B. The HOPS complex subunit VPS39 controls ciliogenesis through autophagy. Hum Mol Genet. 2020;29:1018-1029 pubmed publisher
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| Wang Y, Huang Y, Liu J, Zhang J, Xu M, You Z, et al. Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB. EMBO Rep. 2019;:e48335 pubmed publisher
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| Zemirli N, Boukhalfa A, Dupont N, Botti J, Codogno P, Morel E. The primary cilium protein folliculin is part of the autophagy signaling pathway to regulate epithelial cell size in response to fluid flow. Cell Stress. 2019;3:100-109 pubmed publisher
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| Finetti F, Cassioli C, Cianfanelli V, Onnis A, Paccagnini E, Kabanova A, et al. The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases. Cell Death Differ. 2019;: pubmed publisher
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| Liu W, He X, Yang S, Zouari R, Wang J, Wu H, et al. Bi-allelic Mutations in TTC21A Induce Asthenoteratospermia in Humans and Mice. Am J Hum Genet. 2019;104:738-748 pubmed publisher
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| Wehrle A, Witkos T, Unger S, Schneider J, Follit J, Hermann J, et al. Hypomorphic mutations of TRIP11 cause odontochondrodysplasia. JCI Insight. 2019;4: pubmed publisher
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| Tu H, Qin X, Liu Z, Song Z, Hu H, Zhang Y, et al. Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis. Nat Commun. 2018;9:5277 pubmed publisher
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| Vuolo L, Stevenson N, Heesom K, Stephens D. Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function. elife. 2018;7: pubmed publisher
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| Galati D, Sullivan K, Pham A, Espinosa J, Pearson C. Trisomy 21 Represses Cilia Formation and Function. Dev Cell. 2018;46:641-650.e6 pubmed publisher
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| Kasahara K, Aoki H, Kiyono T, Wang S, Kagiwada H, Yuge M, et al. EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase. Nat Commun. 2018;9:758 pubmed publisher
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| Han S, Jung J, Im S, Lee S, Jang B, Park K, et al. Deficiency of primary cilia in kidney epithelial cells induces epithelial to mesenchymal transition. Biochem Biophys Res Commun. 2018;496:450-454 pubmed publisher
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| Schmid F, Schou K, Vilhelm M, Holm M, Breslin L, Farinelli P, et al. IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases. J Cell Biol. 2018;217:151-161 pubmed publisher
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| Lee S, Joo K, Jung E, Hong H, Seo J, Kim J. Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1. FASEB J. 2018;32:957-968 pubmed publisher
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| Martin L, Kaci N, Estibals V, Goudin N, Garfa Traoré M, Benoist Lasselin C, et al. Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia. Hum Mol Genet. 2018;27:1-13 pubmed publisher
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| Guen V, Chavarria T, Kröger C, Ye X, Weinberg R, Lees J. EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling. Proc Natl Acad Sci U S A. 2017;114:E10532-E10539 pubmed publisher
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| Kurtenbach S, Gießl A, Strömberg S, Kremers J, Atorf J, Rasche S, et al. The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia. Sci Rep. 2017;7:8409 pubmed publisher
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| Katoh Y, Michisaka S, Nozaki S, Funabashi T, Hirano T, Takei R, et al. Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system. Mol Biol Cell. 2017;28:898-906 pubmed publisher
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| Nishita M, Park S, Nishio T, Kamizaki K, Wang Z, Tamada K, et al. Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness. Sci Rep. 2017;7:1 pubmed publisher
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| Fu W, Wang L, Kim S, Li J, Dynlacht B. Role for the IFT-A Complex in Selective Transport to the Primary Cilium. Cell Rep. 2016;17:1505-1517 pubmed publisher
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| Inaba H, Goto H, Kasahara K, Kumamoto K, Yonemura S, Inoko A, et al. Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway. J Cell Biol. 2016;212:409-23 pubmed publisher
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| Vivar O, Masi G, Carpier J, Magalhaes J, Galgano D, Pazour G, et al. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113:386-91 pubmed publisher
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| Shin J, Bae D, Kim E, Kim H, Park S, Jo Y, et al. Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells. Biomol Ther (Seoul). 2015;23:327-32 pubmed publisher
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| Liu F, Chen J, Yu S, Raghupathy R, Liu X, Qin Y, et al. Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish. Hum Mol Genet. 2015;24:4648-59 pubmed publisher
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| Shin J, Kim P, Kim E, Park S, Jo Y, Hwang J, et al. BIX-01294-induced autophagy regulates elongation of primary cilia. Biochem Biophys Res Commun. 2015;460:428-33 pubmed publisher
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| Lu Q, Insinna C, Ott C, Stauffer J, Pintado P, Rahajeng J, et al. Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation. Nat Cell Biol. 2015;17:228-240 pubmed publisher
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