This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Occludin
catalog :
13409-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
dogs
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
citations: 117
Published Application/Species/Sample/DilutionReference
  • western blot; dogs; 1:1000; loading ...; fig 1e
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Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, et al. Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model. J Cell Physiol. 2020;: pubmed publisher
Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, et al. Effects of different concentrations of coated nano Zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets. J Sci Food Agric. 2020;: pubmed publisher
Gao J, Li X, Gao L, Chen H, Baras B, Liu X, et al. Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts. Int J Mol Med. 2020;46:179-190 pubmed publisher
Liu Y, Ma Y, Du B, Wang Y, Yang G, Bi X. Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice. Mol Neurobiol. 2020;: pubmed publisher
Li X, Liu Y, Wang Y, Li X, Liu X, Guo M, et al. Sucralose Promotes Colitis-Associated Colorectal Cancer Risk in a Murine Model Along With Changes in Microbiota. Front Oncol. 2020;10:710 pubmed publisher
Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, et al. Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway. Brain Res Bull. 2020;162:73-83 pubmed publisher
Ma T, Zhou Y, Xia Y, Meng X, Jin H, Wang B, et al. Maternal Exposure to Di-n-butyl Phthalate Promotes the Formation of Testicular Tight Junctions through Downregulation of NF-κB/COX-2/PGE2/MMP-2 in Mouse Offspring. Environ Sci Technol. 2020;54:8245-8258 pubmed publisher
Tian M, Ma P, Zhang Y, Mi Y, Fan D. Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway. Int Immunopharmacol. 2020;85:106645 pubmed publisher
Zhang H, Chen Y, Chen Y, Ji S, Jia P, Li Y, et al. Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets. J Anim Sci Biotechnol. 2020;11:52 pubmed publisher
Ren L, Feng W, Shao J, Ma J, Xu M, Zhu B, et al. Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting. Theranostics. 2020;10:6384-6398 pubmed publisher
Lin H, Chen D, Du Q, Pan T, Tu H, Xu Y, et al. Dietary Copper Plays an Important Role in Maintaining Intestinal Barrier Integrity During Alcohol-Induced Liver Disease Through Regulation of the Intestinal HIF-1α Signaling Pathway and Oxidative Stress. Front Physiol. 2020;11:369 pubmed publisher
Shi Y, Gao F, Yang X, Liu D, Han Q, Liu Z, et al. Increase of BACE1, Brain-Renal Risk Factor, Contributes to Kidney Damage in an Alzheimer's Disease Mouse Model. J Alzheimers Dis. 2020;76:237-248 pubmed publisher
Wang X, Bi X, Huang X, Wang B, Guo Q, Wu Z. Systematic investigation of biomarker-like role of ARHGDIB in breast cancer. Cancer Biomark. 2020;28:101-110 pubmed publisher
Gong Z, Shi X, Bai F, He X, Zhang H, Li Y, et al. Characterization of a Novel Diarrheagenic Strain of Proteus mirabilis Associated With Food Poisoning in China. Front Microbiol. 2019;10:2810 pubmed publisher
He Y, Li X, Yu H, Ge Y, Liu Y, Qin X, et al. The Functional Role of Fecal Microbiota Transplantation on Dextran Sulfate Sodium-Induced Colitis in Mice. Front Cell Infect Microbiol. 2019;9:393 pubmed publisher
Wang J, Zhang C, Guo C, Li X. Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora. Int J Mol Sci. 2019;20: pubmed publisher
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, et al. Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke. Cell Signal. 2019;66:109467 pubmed publisher
Sun D, Yang L, Cao H, Shen Z, Song H. Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells. Cell Biol Int. 2019;: pubmed publisher
Ren M, Gu M, Zhou X, Yu M, Pan H, Ji F, et al. Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis. World J Gastroenterol. 2019;25:5800-5813 pubmed publisher
You M, Miao Z, Pan Y, Hu F. Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway. Eur J Pharmacol. 2019;865:172736 pubmed publisher
Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, et al. Effects of oral florfenicol on intestinal structure, function and microbiota in mice. Arch Microbiol. 2019;: pubmed publisher
He F, Dai R, Zhou X, Li X, Song X, Yan H, et al. Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury. Biomed Pharmacother. 2019;118:109260 pubmed publisher
Li X, Mao M, Zhang Y, Yu K, Zhu W. Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs. Biomolecules. 2019;9: pubmed publisher
Wu D, Deng S, Zhou J, Han R, Liu T, Zhang T, et al. PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer. Int J Cancer. 2019;: pubmed publisher
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z. The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells. Toxicol Lett. 2019;316:109-118 pubmed publisher
Sun X, Yao L, Liang H, Wang D, He Y, Wei Y, et al. Intestinal epithelial PKM2 serves as a safeguard against experimental colitis via activating β-catenin signaling. Mucosal Immunol. 2019;12:1280-1290 pubmed publisher
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, et al. Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9:5065-5084 pubmed publisher
Hu L, Wu C, Zhang Z, Liu M, Maruthi Prasad E, Chen Y, et al. Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota. Front Physiol. 2019;10:908 pubmed publisher
Yu H, Sun J, Zhao C, Wang H, Liu Y, Xiong J, et al. SET domain containing protein 5 (SETD5) enhances tumor cell invasion and is associated with a poor prognosis in non-small cell lung cancer patients. BMC Cancer. 2019;19:736 pubmed publisher
Wu P, Gao Y, Shen S, Xue Y, Liu X, Ruan X, et al. KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis. Cell Death Dis. 2019;10:536 pubmed publisher
Zhang Y, Zhang X, Wei Q, Leng S, Li C, Han B, et al. Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke. Transl Stroke Res. 2019;: pubmed publisher
Zhang Y, Ding X, Miao C, Chen J. Propofol attenuated TNF-α-modulated occludin expression by inhibiting Hif-1α/ VEGF/ VEGFR-2/ ERK signaling pathway in hCMEC/D3 cells. BMC Anesthesiol. 2019;19:127 pubmed publisher
Wang L, Wu Y, Zhuang L, Chen X, Min H, Song S, et al. Puerarin prevents high-fat diet-induced obesity by enriching Akkermansia muciniphila in the gut microbiota of mice. PLoS ONE. 2019;14:e0218490 pubmed publisher
Nan D, Jin H, Deng J, Yu W, Liu R, Sun W, et al. Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress. FASEB J. 2019;33:10152-10164 pubmed publisher
Zhu Z, Yu J, Lin W, Tang H, Zhang W, Lu B. Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions. Mol Med Rep. 2019;19:5177-5184 pubmed publisher
Sun Z, Xie Q, Pan J, Niu N. Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner. Ren Fail. 2019;41:354-362 pubmed publisher
Luo L, Liu Y, Cai X, Wang Y, Xue J, Zhang J, et al. Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells. Saudi J Gastroenterol. 2019;25:302-308 pubmed publisher
He Y, Yu H, Ge Y, Li X, Jiang M, Liu Y, et al. Bacterial β-glucuronidase alleviates dextran sulfate sodium-induced colitis in mice: A possible crucial new diagnostic and therapeutic target for inflammatory bowel disease. Biochem Biophys Res Commun. 2019;513:426-433 pubmed publisher
Van Itallie C, Lidman K, Tietgens A, Anderson J. Newly synthesized claudins but not occludin are added to the basal side of the tight junction. Mol Biol Cell. 2019;30:1406-1424 pubmed publisher
Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, et al. A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function. Front Microbiol. 2019;10:477 pubmed publisher
Ramakrishnan S, Zhang H, Ma X, Jung I, Schwartz A, Triner D, et al. Intestinal non-canonical NFκB signaling shapes the local and systemic immune response. Nat Commun. 2019;10:660 pubmed publisher
Xu J, Wei G, Wang J, Zhu J, Yu M, Zeng X, et al. Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function. Lab Invest. 2019;99:577-587 pubmed publisher
Liao Z, Zhang H, Fan P, Huang Q, Dong K, Qi Y, et al. High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer. Int J Oncol. 2019;54:479-490 pubmed publisher
Wang J, Tian S, Yu H, Wang J, Zhu W. Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets. J Agric Food Chem. 2019;67:578-588 pubmed publisher
Li X, Dong M, Zhou J, Zhu D, Zhao J, Sheng W. C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway. Mol Cell Biochem. 2019;454:87-95 pubmed publisher
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, et al. S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA2 phosphorylation. Cell Signal. 2019;53:151-161 pubmed publisher
Wang S, Li H, Du C, Liu Q, Yang D, Chen L, et al. Effects of dietary supplementation with Lactobacillus acidophilus on the performance, intestinal physical barrier function, and the expression of NOD-like receptors in weaned piglets. Peerj. 2018;6:e6060 pubmed publisher
Wang S, Xie T, Sun S, Wang K, Liu B, Wu X, et al. DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury. Sci Rep. 2018;8:17788 pubmed publisher
Liu W, Lv Y, Yang R, Fu J, Liu L, Wang H, et al. New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis. J Neuroinflammation. 2018;15:291 pubmed publisher
Leng X, Ma J, Liu Y, Shen S, Yu H, Zheng J, et al. Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB. J Exp Clin Cancer Res. 2018;37:246 pubmed publisher
Adegoke E, Xue W, Machebe N, Adeniran S, Hao W, Chen W, et al. Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage. Ecotoxicol Environ Saf. 2018;166:165-175 pubmed publisher
Wu Y, Li T, Zang L, Liu B, Wang G. Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets. Biomed Pharmacother. 2018;107:1447-1453 pubmed publisher
Wu D, Deng S, Liu T, Han R, Zhang T, Xu Y. TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression. Cancer Med. 2018;7:5118-5129 pubmed publisher
Manthari R, Tikka C, Ommati M, Niu R, Sun Z, Wang J, et al. Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood-brain barrier's tight junction proteins. Arch Toxicol. 2018;92:3255-3275 pubmed publisher
Adegoke E, Wang C, Machebe N, Wang X, Wang H, Adeniran S, et al. Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway. Environ Toxicol Pharmacol. 2018;63:115-126 pubmed publisher
Luo L, Zhou Z, Xue J, Wang Y, Zhang J, Cai X, et al. Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats. Exp Ther Med. 2018;16:1715-1722 pubmed publisher
Huang Y, He J, Liang H, Hu K, Jiang S, Yang L, et al. Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis. Front Immunol. 2018;9:1713 pubmed publisher
Kanwal S, Joseph T, Owusu L, Xiaomeng R, Meiqi L, Yi X. A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model. Nutrients. 2018;10: pubmed publisher
Manthari R, Tikka C, Ommati M, Niu R, Sun Z, Wang J, et al. Arsenic-Induced Autophagy in the Developing Mouse Cerebellum: Involvement of the Blood-Brain Barrier's Tight-Junction Proteins and the PI3K-Akt-mTOR Signaling Pathway. J Agric Food Chem. 2018;66:8602-8614 pubmed publisher
Jia Z, Wang X, Wang X, Wei P, Li L, Wu P, et al. Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1?. J Cell Mol Med. 2018;22:4507-4521 pubmed publisher
Zhao M, Xiong X, Ren K, Xu B, Cheng M, Sahu C, et al. Deficiency in intestinal epithelial O-GlcNAcylation predisposes to gut inflammation. EMBO Mol Med. 2018;10: pubmed publisher
Zhang Y, Zhao X, Zhu Y, Ma J, Ma H, Zhang H. Probiotic Mixture Protects Dextran Sulfate Sodium-Induced Colitis by Altering Tight Junction Protein Expressions and Increasing Tregs. Mediators Inflamm. 2018;2018:9416391 pubmed publisher
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, et al. All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway. Neurochem Res. 2018;43:1283-1296 pubmed publisher
Xiao Z, Liu L, Tao W, Pei X, Wang G, Wang M. Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells. Cell Physiol Biochem. 2018;46:1779-1792 pubmed publisher
Wang Y, Kim R, Gunasekara D, Reed M, DiSalvo M, Nguyen D, et al. Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer. Cell Mol Gastroenterol Hepatol. 2018;5:113-130 pubmed publisher
Zhang X, Jiang G, Wu J, Zhou H, Zhang Y, Miao Y, et al. Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1. Oncol Lett. 2018;15:3806-3813 pubmed publisher
Shen S, Yu H, Liu X, Liu Y, Zheng J, Wang P, et al. PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis. Mol Ther Nucleic Acids. 2018;10:412-425 pubmed publisher
Yu M, Wang Q, Ma Y, Li L, Yu K, Zhang Z, et al. Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity. Int J Biol Sci. 2018;14:69-77 pubmed publisher
Adegoke E, Wang X, Wang H, Wang C, Zhang H, Zhang G. Selenium (Na2SeO3) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro. Biol Trace Elem Res. 2018;185:332-343 pubmed publisher
Lu M, Wu J, Hao Z, Shang Y, Xu J, Nan G, et al. Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress. Hepatology. 2018;68:317-332 pubmed publisher
Zhang D, Jin C, Zhang Y, Gan X, Zou M, Wang Y, et al. A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats. J Neuroinflammation. 2018;15:16 pubmed publisher
Liu Z, Li L, Chen W, Wang Q, Xiao W, Ma Y, et al. Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway. Int J Mol Med. 2018;41:1560-1572 pubmed publisher
Dong Y, Wang Z, Qin Z, Cao J, Chen Y. Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea. J Mol Histol. 2018;49:85-97 pubmed publisher
Zhao R, Guo Z, Zhang R, Deng C, Xu J, Dong W, et al. Nasal epithelial barrier disruption by particulate matter ≤2.5 μm via tight junction protein degradation. J Appl Toxicol. 2018;38:678-687 pubmed publisher
Deng J, Zeng L, Lai X, Li J, Liu L, Lin Q, et al. Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation. J Cell Mol Med. 2018;22:546-557 pubmed publisher
Zou Y, Ma L, Zhao Y, Zhang S, Zhou C, Cai Y. Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-?B pathway. Int J Mol Med. 2018;41:430-438 pubmed publisher
Yang S, Jin H, Zhao Z. An ECV304 monoculture model for permeability assessment of blood-brain barrier. Neurol Res. 2018;40:117-121 pubmed publisher
Wang Y, DiSalvo M, Gunasekara D, Dutton J, Proctor A, Lebhar M, et al. Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells. Cell Mol Gastroenterol Hepatol. 2017;4:165-182.e7 pubmed publisher
Li L, Wang N, Jin Q, Wu Q, Liu Y, Wang Y. Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability. Chem Pharm Bull (Tokyo). 2017;65:1004-1010 pubmed publisher
Fang M, Jiang H, Ye L, Cai C, Hu Y, Pan S, et al. Metformin treatment after the hypoxia-ischemia attenuates brain injury in newborn rats. Oncotarget. 2017;8:75308-75325 pubmed publisher
Zhang X, Liu Y, Fan C, Wang L, Li A, Zhou H, et al. Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway. Oncotarget. 2017;8:75102-75113 pubmed publisher
Yang S, Mei S, Jin H, Zhu B, Tian Y, Huo J, et al. Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier. PLoS ONE. 2017;12:e0187017 pubmed publisher
Wang J, Kong H, Xu J, Wang Y, Wang H, Xie W. Fasudil alleviates LPS-induced lung Injury by restoring aquaporin 5 expression and inhibiting inflammation in lungs. J Biomed Res. 2017;: pubmed publisher
Qie X, Wen D, Guo H, Xu G, Liu S, Shen Q, et al. Endoplasmic Reticulum Stress Mediates Methamphetamine-Induced Blood-Brain Barrier Damage. Front Pharmacol. 2017;8:639 pubmed publisher
Wang J, Fu X, Zhang D, Yu L, Lu Z, Gao Y, et al. Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion. Neuroscience. 2017;364:202-211 pubmed publisher
Du J, Zhang X, Zhou H, Miao Y, Han Y, Han Q, et al. Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway. Tumour Biol. 2017;39:1010428317701441 pubmed publisher
Zhang Q, Wang Z, Sun D, Wang Y, Xu P, Wu W, et al. Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity. Oxid Med Cell Longev. 2017;2017:7150376 pubmed publisher
Geoffroy M, Kleinclauss A, Grandemange S, Hupont S, Boisbrun M, Flament S, et al. Pro-apoptotic effect of ?2-TGZ in "claudin-1-low" triple-negative breast cancer cells: involvement of claudin-1. Breast Cancer Res Treat. 2017;165:517-527 pubmed publisher
Zhang X, Cai L, Zhou H, Liu Y, Fan C, Wang L, et al. Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients. Mol Carcinog. 2017;56:2558-2565 pubmed publisher
Wu J, He Z, Yang X, Li K, Wang D, Sun F. RCCD1 depletion attenuates TGF-β-induced EMT and cell migration by stabilizing cytoskeletal microtubules in NSCLC cells. Cancer Lett. 2017;400:18-29 pubmed publisher
Zhang X, Zhou H, Zhang Y, Cai L, Jiang G, Li A, et al. ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients. Oncotarget. 2017;8:38863-38875 pubmed publisher
Han J, Li J, Bai G, Shen G, Chen J, Liu J, et al. Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-?B/MLCK pathway in a mouse endotoxemia model. World J Gastroenterol. 2017;23:2175-2184 pubmed publisher
Hu Y, Wang Z, Pan S, Zhang H, Fang M, Jiang H, et al. Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-κB signaling pathway after LPS treatment in neonatal rats. Oncotarget. 2017;8:31638-31654 pubmed publisher
Zhang X, Zhou H, Cai L, Fan C, Liu Y, Wang L, et al. Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients. Mol Carcinog. 2017;56:2058-2065 pubmed publisher
He F, Duan X, Dai R, Li Y, Lin Q. Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood-Brain Barrier after Cerebral Ischemia Reperfusion Injury. J Stroke Cerebrovasc Dis. 2017;26:1258-1265 pubmed publisher
Xia Z, Han Y, Wang K, Guo S, Wu D, Huang X, et al. Oral administration of propionic acid during lactation enhances the colonic barrier function. Lipids Health Dis. 2017;16:62 pubmed publisher
Li Y, Xu B, Xu M, Chen D, Xiong Y, Lian M, et al. 6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling. Pharmacol Res. 2017;119:137-148 pubmed publisher
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J. Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells. Diabetes Res Clin Pract. 2017;124:30-40 pubmed publisher
Zhang X, Jiang G, Sun M, Zhou H, Miao Y, Liang M, et al. Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway. Oncotarget. 2017;8:13357-13366 pubmed publisher
Lin C, Wang L, Wang S, Chang Y, Wu Y, Chen H, et al. Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1?/HDAC1/Slug axis. Nat Commun. 2016;7:13867 pubmed publisher
Li C, Liu C, Tsai C, Peng Y, Yang Y, Liao P, et al. Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells. Arch Toxicol. 2017;91:2165-2178 pubmed publisher
Yang R, Liu W, Miao L, Yang X, Fu J, Dou B, et al. Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier. Oncotarget. 2016;7:63839-63855 pubmed publisher
Yang Z, Wang X, Chi X, Zhao F, Guo J, Ma P, et al. Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection. J Virol. 2016;90:9632-9643 pubmed publisher
Lu D, Qu Y, Shi F, Feng D, Tao K, Gao G, et al. Activation of G protein-coupled estrogen receptor 1 (GPER-1) ameliorates blood-brain barrier permeability after global cerebral ischemia in ovariectomized rats. Biochem Biophys Res Commun. 2016;477:209-14 pubmed publisher
Zhang J, Li Z, Qie M, Zheng R, Shetty J, Wang J. Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice. Food Chem Toxicol. 2016;94:103-11 pubmed publisher
Yamamoto S, Fukuhara T, Ono C, Uemura K, Kawachi Y, Shiokawa M, et al. Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus. PLoS Pathog. 2016;12:e1005610 pubmed publisher
Han J, Xu Y, Yang D, Yu N, Bai Z, Bian L. Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice. Asian-Australas J Anim Sci. 2016;29:134-41 pubmed publisher
Gong Y, Li H, Li Y. Effects of Bacillus subtilis on Epithelial Tight Junctions of Mice with Inflammatory Bowel Disease. J Interferon Cytokine Res. 2016;36:75-85 pubmed publisher
Wang Z, Cheng Y, Yu X, Ye L, Xia Q, Johnson N, et al. bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury. Mol Neurobiol. 2016;53:7298-7311 pubmed
Han J, Liu L, Yu N, Chen J, Liu B, Yang D, et al. Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice. Anim Sci J. 2016;87:1011-8 pubmed publisher
Ridder D, Wenzel J, Müller K, Töllner K, Tong X, Assmann J, et al. Brain endothelial TAK1 and NEMO safeguard the neurovascular unit. J Exp Med. 2015;212:1529-49 pubmed publisher
Yu X, Zhang X, Zhang Y, Jiang G, Mao X, Jin F. Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl. Oncotarget. 2015;6:25034-45 pubmed publisher
Li C, Shyu M, Jhan C, Cheng Y, Tsai C, Liu C, et al. Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice. Toxicol Sci. 2015;148:192-203 pubmed publisher
Zhang X, Miao Y, Yu X, Zhang Y, Jiang G, Liu Y, et al. C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn. Tumour Biol. 2015;36:5979-85 pubmed publisher
Shao S, Zhao X, Zhang X, Luo M, Zuo X, Huang S, et al. Notch1 signaling regulates the epithelial-mesenchymal transition and invasion of breast cancer in a Slug-dependent manner. Mol Cancer. 2015;14:28 pubmed publisher
Zhang X, Zhao X, Shao S, Zuo X, Ning Q, Luo M, et al. Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role. Int J Oncol. 2015;46:1141-8 pubmed publisher
product information
CatalogNo :
13409-1-AP
AntigenName :
Occludin
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
occludin
Immunogen :
Recombinant Protein
Species :
cow, human, mouse, rat, swine
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
occludin, OCLN
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC029886
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:800 ; IP 1:500 ; WB 1:5000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.