This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
HSP90
catalog :
13171-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 59
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 4b
Lei X, Cui K, Liu Q, Zhang H, Li Z, Huang B, et al. Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway. Reprod Domest Anim. 2016;51:75-84 pubmed publisher
Sha L, Chen T, Deng Y, Du T, Ma K, Zhu W, et al. Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity. Theranostics. 2020;10:8415-8429 pubmed publisher
Wang H, Wang L, Zhou X, Luo X, Liu K, Jiang E, et al. OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway. Biomed Res Int. 2020;2020:2125656 pubmed publisher
Di Nardo A, Leno l I, Winden K, R hmkorf A, Modi M, Barrett L, et al. Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia. Cell Rep. 2020;31:107780 pubmed publisher
Sun K, Wang X, Fang N, Xu A, Lin Y, Zhao X, et al. SIRT2 suppresses expression of inflammatory factors via Hsp90-glucocorticoid receptor signalling. J Cell Mol Med. 2020;: pubmed publisher
Zhang P, Li C, Li H, Yuan L, Dai H, Peng Z, et al. Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer. Cell Death Differ. 2020;: pubmed publisher
Liu Y, Huang X, Nguyen D, Shammas M, Wu B, Dombi E, et al. Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations. Hum Mol Genet. 2020;29:1547-1567 pubmed publisher
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, et al. Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biol. 2020;32:101514 pubmed publisher
Ren J, Zhang L, Zhang J, Zhang W, Cao Y, Xu Z, et al. Light-activated oxygen self-supplied starving therapy in near-infrared (NIR) window and adjuvant hyperthermia-induced tumor ablation with an augmented sensitivity. Biomaterials. 2020;234:119771 pubmed publisher
Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, et al. LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress. Biomed Pharmacother. 2020;123:109803 pubmed publisher
Zuo Y, He T, Liao P, Zhuang K, Yan X, Liu F. 17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Subarachnoid Hemorrhage in Rats. Acta Neurochir Suppl. 2020;127:69-75 pubmed publisher
Liu Y, Yin W, Wang J, Lei Y, Sun G, Li W, et al. KRAB-Zinc Finger Protein ZNF268a Deficiency Attenuates the Virus-Induced Pro-Inflammatory Response by Preventing IKK Complex Assembly. Cells. 2019;8: pubmed publisher
Hong W, Guo F, Yang M, Xu D, Zhuang Z, Niu B, et al. Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent. Lipids Health Dis. 2019;18:203 pubmed publisher
Santiago J, Silva J, Fardilha M. First Insights on the Presence of the Unfolded Protein Response in Human Spermatozoa. Int J Mol Sci. 2019;20: pubmed publisher
Chen P, Wang B, Mo Q, Wu P, Fang Y, Tian Y, et al. The LIV-1-GRPEL1 axis adjusts cell fate during anti-mitotic agent-damaged mitosis. EBioMedicine. 2019;49:26-39 pubmed publisher
Jurivich D, Manocha G, Trivedi R, Lizakowski M, Rakoczy S, Brown Borg H. Multifactorial Attenuation of the Murine Heat Shock Response With Age. J Gerontol A Biol Sci Med Sci. 2019;: pubmed publisher
Kueck T, Bloyet L, Cassella E, Zang T, Schmidt F, Brusic V, et al. Vesicular Stomatitis Virus Transcription Is Inhibited by TRIM69 in the Interferon-Induced Antiviral State. J Virol. 2019;93: pubmed publisher
Yang X, Zhao H, Wang Y, Liu J, Guo M, Fei D, et al. The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum. Biol Trace Elem Res. 2019;: pubmed publisher
Kato R, Ijiri Y, Hayashi T, Uetrecht J. The 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes; Implications for Carbamazepine-induced Hypersensitivity Reactions. Drug Metab Dispos. 2019;: pubmed publisher
Wang T, Cao Y, Zheng Q, Tu J, Zhou W, He J, et al. SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism. Mol Cell. 2019;75:823-834.e5 pubmed publisher
Niu L, Ma T, Yang F, Yan B, Tang X, Yin H, et al. Atlastin-mediated membrane tethering is critical for cargo mobility and exit from the endoplasmic reticulum. Proc Natl Acad Sci U S A. 2019;116:14029-14038 pubmed publisher
Rinaldi L, Delle Donne R, Catalanotti B, Torres Quesada O, Enzler F, Moraca F, et al. Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system. Nat Commun. 2019;10:2572 pubmed publisher
Zhao A, Guo L, Xu J, Zheng L, Guo Z, Ling Z, et al. Identification and validation of circulating exosomes-based liquid biopsy for esophageal cancer. Cancer Med. 2019;: pubmed publisher
Wang D, Chen J, Yu C, Zhu X, Xu S, Fang L, et al. Porcine Reproductive and Respiratory Syndrome Virus Nsp11 Antagonizes Type I Interferon Signaling by Targeting IRF9. J Virol. 2019;: pubmed publisher
Wu Z, Geng Y, Lu X, Shi Y, Wu G, Zhang M, et al. Chaperone-mediated autophagy is involved in the execution of ferroptosis. Proc Natl Acad Sci U S A. 2019;116:2996-3005 pubmed publisher
Wang S, Huang Y, Yan Y, Zhou H, Wang M, Liao L, et al. Calpain2 but not calpain1 mediated by calpastatin following glutamate-induced regulated necrosis in rat retinal neurons. Ann Anat. 2019;221:57-67 pubmed publisher
Zuo Y, Wang J, Liao F, Yan X, Li J, Huang L, et al. Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice. Front Mol Neurosci. 2018;11:401 pubmed publisher
Zhou X, Yan T, HUANG C, Xu Z, Wang L, Jiang E, et al. Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway. J Exp Clin Cancer Res. 2018;37:242 pubmed publisher
Gao P, Wang X, Jin Y, Hu W, Duan Y, Shi A, et al. Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells. Breast Cancer Res. 2018;20:112 pubmed publisher
Xiao X, Wang W, Li Y, Yang D, Li X, Shen C, et al. HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma. J Exp Clin Cancer Res. 2018;37:201 pubmed publisher
Liu J, Zhao H, Wang Y, Shao Y, Zhang L, Xing M. Impacts of simultaneous exposure to arsenic (III) and copper (II) on inflammatory response, immune homeostasis, and heat shock response in chicken thymus. Int Immunopharmacol. 2018;64:60-68 pubmed publisher
Xu W, Zhou B, Zhao X, Zhu L, Xu J, Jiang Z, et al. KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance. Int J Biol Sci. 2018;14:1122-1132 pubmed publisher
Eguchi K, Shindo T, Ito K, Ogata T, Kurosawa R, Kagaya Y, et al. Whole-brain low-intensity pulsed ultrasound therapy markedly improves cognitive dysfunctions in mouse models of dementia - Crucial roles of endothelial nitric oxide synthase. Brain Stimul. 2018;11:959-973 pubmed publisher
Jiang W, Wei Y, Long Y, Owen A, Wang B, Wu X, et al. A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans. elife. 2018;7: pubmed publisher
Jin Y, Hu W, Liu T, Rana U, Aguilera Barrantes I, Kong A, et al. Nogo-B receptor increases the resistance of estrogen receptor positive breast cancer to paclitaxel. Cancer Lett. 2018;419:233-244 pubmed publisher
Liu X, Lu J, Liu Z, Zhao J, Sun H, Wu N, et al. Intestinal Epithelial Cell-Derived LKB1 Suppresses Colitogenic Microbiota. J Immunol. 2018;200:1889-1900 pubmed publisher
Jia W, Zhao X, Zhao L, Yan H, Li J, Yang H, et al. Non-canonical roles of PFKFB3 in regulation of cell cycle through binding to CDK4. Oncogene. 2018;37:1685-1698 pubmed publisher
Wang Z, Guo L, Wang Y, Zhou H, Wang S, Chen D, et al. Inhibition of HSP90α protects cultured neurons from oxygen-glucose deprivation induced necroptosis by decreasing RIP3 expression. J Cell Physiol. 2018;233:4864-4884 pubmed publisher
Shao Y, Zhao H, Wang Y, Liu J, Li J, Chai H, et al. Arsenic and/or copper caused inflammatory response via activation of inducible nitric oxide synthase pathway and triggered heat shock protein responses in testis tissues of chicken. Environ Sci Pollut Res Int. 2018;25:7719-7729 pubmed publisher
Lant J, Berg M, Sze D, Hoffman K, Akinpelu I, Turk M, et al. Visualizing tRNA-dependent mistranslation in human cells. RNA Biol. 2018;15:567-575 pubmed publisher
Lian S, Guo J, Wang L, Li W, Wang J, Ji H, et al. Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats. Oncotarget. 2017;8:115304-115314 pubmed publisher
Deng X, Song L, Zhao W, Wei Y, Guo X. HAX-1 Protects Glioblastoma Cells from Apoptosis through the Akt1 Pathway. Front Cell Neurosci. 2017;11:420 pubmed publisher
Chang C, Liu W, Hung H, Gean C, Tsai H, Su C, et al. Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells. BMC Cancer. 2017;17:905 pubmed publisher
Zeng H, Yang Q, Du H, Li H, Shen Y, Liu T, et al. Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats. Oncotarget. 2017;8:102020-102032 pubmed publisher
Wang Y, Zhao H, Shao Y, Liu J, Li J, Xing M. Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken. Oncotarget. 2017;8:98103-98116 pubmed publisher
Zhang J, Wang Y, Zhou Y, He Q. Jolkinolide B induces apoptosis of colorectal carcinoma through ROS-ER stress-Ca2+-mitochondria dependent pathway. Oncotarget. 2017;8:91223-91237 pubmed publisher
Liu W, Liu X, Li Y, Zhao J, Liu Z, Hu Z, et al. LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection. J Exp Med. 2017;214:3051-3066 pubmed publisher
Li S, Guo Y, He Y, Sun X, Zhao H, Wang Y, et al. Assessment of arsenic trioxide toxicity on cock muscular tissue: alterations of oxidative damage parameters, inflammatory cytokines and heat shock proteins. Ecotoxicology. 2017;26:1078-1088 pubmed publisher
Li H, Wang S, Chen Y, Lu K, Yin B, Li S, et al. Identification of two p53 isoforms from Litopenaeus vannamei and their interaction with NF-κB to induce distinct immune response. Sci Rep. 2017;7:45821 pubmed publisher
Li R, Yuan F, Fu W, Zhang L, Zhang N, Wang Y, et al. Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins. J Biol Chem. 2017;292:2830-2841 pubmed publisher
Zhang F, Hao M, Jin H, Yao Z, Lian N, Wu L, et al. Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis. Br J Pharmacol. 2017;174:409-423 pubmed publisher
Sun B, Bai Y, Zhang L, Gong L, Qi X, Li H, et al. Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells. PLoS ONE. 2016;11:e0163622 pubmed publisher
Mo Q, Zhang Y, Jin X, Gao Y, Wu Y, Hao X, et al. Geldanamycin, an inhibitor of Hsp90, increases paclitaxel-mediated toxicity in ovarian cancer cells through sustained activation of the p38/H2AX axis. Tumour Biol. 2016;37:14745-14755 pubmed
Chen Z, Yang L, Cui Y, Zhou Y, Yin X, Guo J, et al. Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages. Oncotarget. 2016;7:67387-67402 pubmed publisher
Zhao F, Fang L, Wang D, Song T, Wang T, Xin Y, et al. SILAC-based quantitative proteomic analysis of secretome of Marc-145 cells infected with porcine reproductive and respiratory syndrome virus. Proteomics. 2016;16:2678-2687 pubmed publisher
Lu Y, Wang J, Dapeng C, Wu D, Cai G, Chen X. Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells. BMC Nephrol. 2016;17:39 pubmed publisher
Gritsyna Y, Abdusalamova Z, Vikhlyantsev I, Ulanova A, Shenkman B, Podlubnaya Z, et al. Changes in gene expression and content of Hsp70 and Hsp90 in striated muscles of mice after 30-day space flight on the biosatellite Bion-M1. Dokl Biochem Biophys. 2015;463:199-202 pubmed publisher
Li D, Xu T, Cao Y, Wang H, Li L, Chen S, et al. A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis. Proc Natl Acad Sci U S A. 2015;112:5017-22 pubmed publisher
Wei B, Cui Y, Huang Y, Liu H, Li L, Li M, et al. Tom70 mediates Sendai virus-induced apoptosis on mitochondria. J Virol. 2015;89:3804-18 pubmed publisher
product information
CatalogNo :
13171-1-AP
AntigenName :
HSP90
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
heat shock protein 90kDa alpha (cytosolic), class A member 1
Immunogen :
Recombinant Protein
Species :
chick, chicken, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, CoIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Heat shock 86 kDa, HSP 86, HSP86, Hsp89, HSP89A, HSP90, HSP90A, HSP90AA1, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, LAP2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC023006
Category :
Binding Proteins;Disease Related;Immunology;Membrane Proteins;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:3 ; IF 1:25 ; IHC 1:50 ; IP 1:500 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.