| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; rat; 1:1000; loading ...; fig 5e
| Yu J, Wang W, Matei N, Li X, Pang J, Mo J, et al. Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats. Oxid Med Cell Longev. 2020;2020:4717258 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 2g
| Burrus C, McKinstry S, Kim N, Ozlu M, Santoki A, Fang F, et al. Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival. Cell Rep. 2020;30:642-657.e6 pubmed publisher |
- western blot; human; 1:5000; loading ...; fig 2e
| Ding X, Hu H, Huang K, Wei R, Min J, Qi C, et al. Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma. Cancer Sci. 2020;111:489-501 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 6j
| Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, et al. A DNAH17 missense variant causes flagella destabilization and asthenozoospermia. J Exp Med. 2020;217: pubmed publisher |
- western blot; human; 1:3000; loading ...; fig 3b
| Yang L, Hong Q, Xu S, Kuang X, Di G, Liu G, et al. Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway. Mol Med Rep. 2019;20:4045-4258 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s12a
| Xu B, Lang L, Li S, Guo J, Wang J, Yang H, et al. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. 2019;9: pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 4a
| Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, et al. Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro. Med Sci Monit. 2019;25:5375-5388 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 6f
| Lu Y, Wan J, Yang Z, Lei X, Niu Q, Jiang L, et al. Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells. FASEB J. 2017;31:1382-1397 pubmed publisher |
- western blot; human; 1:2000; fig 2
| Ren Y, Zhao P, Liu J, Yuan Y, Cheng Q, Zuo Y, et al. Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus. PLoS Pathog. 2016;12:e1005764 pubmed publisher |
- western blot; human; fig 1b
| Jiang P, Gan M, Yen S, Moussaud S, McLean P, Dickson D. Proaggregant nuclear factor(s) trigger rapid formation of ?-synuclein aggregates in apoptotic neurons. Acta Neuropathol. 2016;132:77-91 pubmed publisher |
| Li Y, Wu L, Zeng L, Zhang Z, Wang W, Zhang C, et al. ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT3. Oncogene. 2020;: pubmed publisher |
| Sun Y, He L, Wang T, Hua W, Qin H, Wang J, et al. Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells. Mol Neurobiol. 2020;: pubmed publisher |
| Chen Y, Wu Y, Yu S, Yang H, Wang X, Zhang Y, et al. Deficiency of microRNA-628-5p promotes the progression of gastric cancer by upregulating PIN1. Cell Death Dis. 2020;11:559 pubmed publisher |
| Li S, Huang D, Shen S, Cai Y, Xing S, Wu G, et al. Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis. Nat Metab. 2020;2:256-269 pubmed publisher |
| Li C, Wang L, Liu J, Yu Y, Huang Y, Huang X, et al. Singapore Grouper Iridovirus (SGIV) Inhibited Autophagy for Efficient Viral Replication. Front Microbiol. 2020;11:1446 pubmed publisher |
| Wu Y, Wang Z, Fu X, Lin Z, Yu K. Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies. Int Immunopharmacol. 2020;86:106713 pubmed publisher |
| Wu Y, Wang Z, Lin Z, Fu X, Zhan J, Yu K. Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo. Front Pharmacol. 2020;11:682 pubmed publisher |
| Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, et al. WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling. Oxid Med Cell Longev. 2020;2020:7950457 pubmed publisher |
| Cui Y, Li F, Xie Q, Zhao S, Guo T, Guo P, et al. YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC. Cell Death Dis. 2020;11:476 pubmed publisher |
| Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, et al. PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition. J Cell Mol Med. 2020;: pubmed publisher |
| Li Y, Wu J, Yu S, Zhu J, Zhou Y, Wang P, et al. Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats. Brain Res. 2020;1745:146948 pubmed publisher |
| You R, Zhou W, Li Y, Zhang Y, Huang S, Jia Z, et al. Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells. Clin Sci (Lond). 2020;134:1357-1376 pubmed publisher |
| Xu H, Wang H, Zhao W, Fu S, Li Y, Ni W, et al. SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma. Theranostics. 2020;10:5671-5686 pubmed publisher |
| Fujiwara Tani R, Fujii K, Mori S, Kishi S, Sasaki T, Ohmori H, et al. Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/ Polyps with Dysplasia. Int J Mol Sci. 2020;21: pubmed publisher |
| Mao K, Chen J, Yu H, Li H, Ren Y, Wu X, et al. Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease. Aging Cell. 2020;19:e13163 pubmed publisher |
| Xu H, Qi Q, Yan X. Myricetin ameliorates sepsis-associated acute lung injury in a murine sepsis model. Naunyn Schmiedebergs Arch Pharmacol. 2020;: pubmed publisher |
| Xu B, Qin T, Yu J, Giordano T, Sartor M, Koenig R. Novel role of ASH1L histone methyltransferase in anaplastic thyroid carcinoma. J Biol Chem. 2020;295:8834-8845 pubmed publisher |
| Sun Q, Fan G, Zhuo Q, Dai W, Ye Z, Ji S, et al. Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop. Cell Prolif. 2020;53:e12816 pubmed publisher |
| Guo X, Lin H, Liu J, Wang D, Li D, Jiang C, et al. 1,25-Dihydroxyvitamin D attenuates diabetic cardiac autophagy and damage by vitamin D receptor-mediated suppression of FoxO1 translocation. J Nutr Biochem. 2020;80:108380 pubmed publisher |
| Zhao X, Shi Y, Zhang D, Tong X, Sun Y, Xue X, et al. Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia. Life Sci. 2020;252:117662 pubmed publisher |
| Zhang Y, Zhang X, Liang Z, Dai K, Zhu M, Zhang M, et al. Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling. Aquaculture. 2020;520:734969 pubmed publisher |
| Zhang X, Feng J, Su S, Huang L. Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling. Pharm Biol. 2020;58:239-246 pubmed publisher |
| Pan B, Liu L, Hu X, Sun X, Zhu Y, Zhang T, et al. Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3. J Gastroenterol Hepatol. 2020;: pubmed publisher |
| Zavaczki E, Gáll T, Zarjou A, Hendrik Z, Potor L, Tóth C, et al. Ferryl Hemoglobin Inhibits Osteoclastic Differentiation of Macrophages in Hemorrhaged Atherosclerotic Plaques. Oxid Med Cell Longev. 2020;2020:3721383 pubmed publisher |
| Yu Y, Cai L, Wang X, Cheng S, Zhang D, Jian W, et al. BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma. Cancer Sci. 2020;111:1555-1566 pubmed publisher |
| Zuo Y, Feng Q, Jin L, Huang F, Miao Y, Liu J, et al. Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling. Nat Commun. 2020;11:1146 pubmed publisher |
| Du J, He W, Zhang C, Wu J, Li Z, Wang M, et al. Pentamethylquercetin Attenuates Cardiac Remodeling via Activation of the Sestrins/Keap1/Nrf2 Pathway in MSG-Induced Obese Mice. Biomed Res Int. 2020;2020:3243906 pubmed publisher |
| Posta N, Csosz E, Oros M, Pethő D, Potor L, Kalló G, et al. Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction. Lab Invest. 2020;100:986-1002 pubmed publisher |
| Wang Y, Yang Y, Zuo R, Wu J, Zhang C, Li C, et al. FOXO3 protects nucleus pulposus cells against apoptosis under nutrient deficiency via autophagy. Biochem Biophys Res Commun. 2020;524:756-763 pubmed publisher |
| Kang L, Liu S, Li J, Tian Y, Xue Y, Liu X. The mitochondria-targeted anti-oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance. Cell Prolif. 2020;53:e12779 pubmed publisher |
| Zhang G, Yu X, Sun J, Xiong J, Yang Y, Jiang X, et al. UBE2M promotes cell proliferation via the β-catenin/cyclin D1 signaling in hepatocellular carcinoma. Aging (Albany NY). 2020;12:2373-2392 pubmed publisher |
| He H, Xu C, Zheng L, Wang K, Jin M, Sun Y, et al. Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells. Mol Med Rep. 2020;21:597-606 pubmed publisher |
| He X, Chen S, Li C, Ban J, Wei Y, He Y, et al. Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages. Cells. 2020;9: pubmed publisher |
| Xu A, Yang Y, Shao Y, Wu M, Sun Y. Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation. Cell Commun Signal. 2020;18:9 pubmed publisher |
| Kong Q, Li Y, Liang Q, Xie J, Li X, Fang J. SIRT6-PARP1 is involved in HMGB1 polyADP-ribosylation and acetylation and promotes chemotherapy-induced autophagy in leukemia. Cancer Biol Ther. 2020;21:320-331 pubmed publisher |
| Huang H, Cai H, Zhang L, Hua Z, Shi J, Wei Y. Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice. Int Immunopharmacol. 2020;80:106123 pubmed publisher |
| Lee D, Park J, Lee Y, Han J, Lee D, Kwon S, et al. SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity. Autophagy. 2020;:1-25 pubmed publisher |
| Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, et al. Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter. Aging (Albany NY). 2020;12:611-627 pubmed publisher |
| Li Y, Xie J, Li X, Fang J. Poly (ADP-ribosylation) of HMGB1 facilitates its acetylation and promotes HMGB1 translocation-associated chemotherapy-induced autophagy in leukaemia cells. Oncol Lett. 2020;19:368-378 pubmed publisher |
| Kang L, Liu S, Li J, Tian Y, Xue Y, Liu X. Parkin and Nrf2 prevent oxidative stress-induced apoptosis in intervertebral endplate chondrocytes via inducing mitophagy and anti-oxidant defenses. Life Sci. 2020;243:117244 pubmed publisher |
| Wang Q, Shi W, Zhang Q, Feng W, Wang J, Zhai C, et al. Inhibition of Siah2 ubiquitin ligase ameliorates monocrotaline-induced pulmonary arterial remodeling through inactivation of YAP. Life Sci. 2020;242:117159 pubmed publisher |
| Li G, Li A, Chen X, Zhang L, Wang T, Wang X, et al. Naturally-derived diterpenoid sphaeropsidin C as an activator of Nrf2/ARE pathway and its potential capability of relieving intracellular oxidative stress in human lung epithelial cells. Biomed Pharmacother. 2020;121:109669 pubmed publisher |
| Yen W, Wu Y, Wu C, Lin H, Stern A, Chen S, et al. Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling. Redox Biol. 2020;28:101363 pubmed publisher |
| Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, et al. Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro. Oxid Med Cell Longev. 2019;2019:6521218 pubmed publisher |
| Wang J, Li L, Wang J, Song L, Tan N, Wang Z. Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells. Cells. 2019;8: pubmed publisher |
| Wan W, Wang L, Chen X, Zhu S, Shang W, Xiao G, et al. A Subcellular Quantitative Proteomic Analysis of Herpes Simplex Virus Type 1-Infected HEK 293T Cells. Molecules. 2019;24: pubmed publisher |
| Yang P, Hong Y, Hsu K, Liu T. p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma. Am J Cancer Res. 2019;9:2120-2139 pubmed |
| Hu Y, Wang C, Ha S, Zhu N, Cao Z, Song Y. Peroxisome proliferator activated receptor γ promotes mineralization and differentiation in cementoblasts via inhibiting Wnt/β-catenin signaling pathway. J Cell Biochem. 2019;: pubmed publisher |
| Shanley K, Hu C, Bizzozero O. Decreased levels of constitutive proteasomes in experimental autoimmune encephalomyelitis may be caused by a combination of subunit displacement and reduced Nfe2l1 expression. J Neurochem. 2019;: pubmed publisher |
| Wang G, Jiang L, Wang J, Zhang J, Kong F, Li Q, et al. The G protein-coupled receptor FFAR2 promotes internalization during influenza A virus entry. J Virol. 2019;: pubmed publisher |
| Wang Y, Yuan S, Jia X, Ge Y, Ling T, Nie M, et al. Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS. Nat Cell Biol. 2019;21:1346-1356 pubmed publisher |
| Liang B, Chen R, Song S, Wang H, Sun G, Yang H, et al. ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma. Cell Death Dis. 2019;10:830 pubmed publisher |
| Ruan J, Cao Y, Ling T, Li P, Wu S, Peng D, et al. DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS. Front Immunol. 2019;10:2202 pubmed publisher |
| Cao L, Ji Y, Zeng L, Liu Q, Zhang Z, Guo S, et al. P200 family protein IFI204 negatively regulates type I interferon responses by targeting IRF7 in nucleus. PLoS Pathog. 2019;15:e1008079 pubmed publisher |
| Shu G, Qiu Y, Hao J, Fu Q, Deng X. γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways. Food Funct. 2019;10:6858-6872 pubmed publisher |
| Li T, Xu L, Teng J, Ma Y, Liu W, Wang Y, et al. GADD45G Interacts with E-cadherin to Suppress the Migration and Invasion of Esophageal Squamous Cell Carcinoma. Dig Dis Sci. 2019;: pubmed publisher |
| Hu Y, Gui Z, Zhou Y, Xia L, Lin K, Xu Y. Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages. Free Radic Biol Med. 2019;145:146-160 pubmed publisher |
| Yang J, Zhang L, Cao L, Qi J, Li P, Wang X, et al. MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model. Cells. 2019;8: pubmed publisher |
| Xu B, Lang L, Li S, Yuan J, Wang J, Yang H, et al. Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure. Animals (Basel). 2019;9: pubmed publisher |
| Yap J, Tai Y, Fröhlich J, Fong C, Yin J, Foo Z, et al. Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism. FASEB J. 2019;33:12853-12872 pubmed publisher |
| Li N, Wang T, Li Z, Ye X, Deng B, Zhuo S, et al. Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels. Cancer Biol Med. 2019;16:220-233 pubmed publisher |
| Zhang X, Chen Y, Zhao Y, Liu W, Hayashi T, Mizuno K, et al. Type I collagen or gelatin stimulates mouse peritoneal macrophages to aggregate and produce pro-inflammatory molecules through upregulated ROS levels. Int Immunopharmacol. 2019;76:105845 pubmed publisher |
| Liu Q, Xie W, Wang Y, Chen S, Han J, Wang L, et al. JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model. Lab Invest. 2019;99:1810-1821 pubmed publisher |
| Ren J, Han Y, Ren T, Fang H, Xu X, Lun Y, et al. AEBP1 Promotes the Occurrence and Development of Abdominal Aortic Aneurysm by Modulating Inflammation via the NF-κB Pathway. J Atheroscler Thromb. 2019;: pubmed publisher |
| Li Y, Ding K, Hu X, Wu L, Zhou D, Rao M, et al. DYRK1A inhibition suppresses STAT3/EGFR/Met signalling and sensitizes EGFR wild-type NSCLC cells to AZD9291. J Cell Mol Med. 2019;: pubmed publisher |
| Zhang K, He M, Wang F, Zhang H, Li Y, Yang J, et al. Revealing Antidepressant Mechanisms of Baicalin in Hypothalamus Through Systems Approaches in Corticosterone- Induced Depressed Mice. Front Neurosci. 2019;13:834 pubmed publisher |
| Cao P, Luo W, Li C, Tong Z, Zheng Z, Zhou L, et al. The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors. PLoS Pathog. 2019;15:e1007983 pubmed publisher |
| Sun Z, Li M, Bai L, Fu J, Lu J, Wu M, et al. Arsenic trioxide inhibits angiogenesis in vitro and in vivo by upregulating FoxO3a. Toxicol Lett. 2019;315:1-8 pubmed publisher |
| Li M, Xu S, Geng Y, Sun L, Wang R, Yan Y, et al. The protective effects of L-carnitine on myocardial ischaemia-reperfusion injury in patients with rheumatic valvular heart disease undergoing CPB surgery are associated with the suppression of NF-κB pathway and the activation of Nrf2 pathway. Clin Exp Pharmacol Physiol. 2019;46:1001-1012 pubmed publisher |
| Diao H, Cheng N, Zhao Y, Xu H, Dong H, Thamm D, et al. Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling. BMC Vet Res. 2019;15:276 pubmed publisher |
| Le K, Chibaatar Daliv E, Wu S, Qian F, Ali A, Yu D, et al. SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury. Int Immunopharmacol. 2019;75:105779 pubmed publisher |
| Li D, Fu S, Wu Z, Yang W, Ru Y, SHU H, et al. DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import. J Cell Sci. 2019;133: pubmed publisher |
| Lu S, Zhang J, Lian X, Sun L, Meng K, Chen Y, et al. A hidden human proteome encoded by 'non-coding' genes. Nucleic Acids Res. 2019;47:8111-8125 pubmed publisher |
| Tian S, Lei P, Teng C, Sun Y, Song X, Li B, et al. Targeting PLIN2/PLIN5-PPARγ: Sulforaphane Disturbs the Maturation of Lipid Droplets. Mol Nutr Food Res. 2019;:e1900183 pubmed publisher |
| Zhang Q, Liu R, Chan K, Hu J, Zhang J, Wei L, et al. Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells. J Exp Clin Cancer Res. 2019;38:320 pubmed publisher |
| Yang T, Zhou R, Yu S, Yu S, Cui Z, Hu P, et al. Cytoplasmic SIRT1 inhibits cell migration and invasion by impeding epithelial-mesenchymal transition in ovarian carcinoma. Mol Cell Biochem. 2019;459:157-169 pubmed publisher |
| Zhong Y, Chen J, Chen J, Chen Y, Li L, Xie Y. Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injury. J Neurochem. 2019;: pubmed publisher |
| Wu X, Chen X, Zhou M, Hu H, Zhang J, Wang X, et al. Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells. Chem Biol Interact. 2019;310:108741 pubmed publisher |
| Yang X, Wang G, Cao T, Zhang L, Ma Y, Jiang S, et al. Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia. J Biol Chem. 2019;294:12921-12932 pubmed publisher |
| Wang F, Liu J, Chen X, Zheng X, Qu N, Zhang B, et al. IL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes. Arthritis Res Ther. 2019;21:171 pubmed publisher |
| Liu L, Qu Y, Liu Y, Zhao H, Ma H, Noor A, et al. Atsttrin reduces lipopolysaccharide-induced neuroinflammation by inhibiting the nuclear factor kappa B signaling pathway. Neural Regen Res. 2019;14:1994-2002 pubmed publisher |
| Zhang Y, Wang H, Yin T, Liu Y, Zhou W, Fan X, et al. TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin. Exp Cell Res. 2019;:111491 pubmed publisher |
| Zhang K, Kuang L, Xia F, Chen Y, Zhang W, Zhai H, et al. Follicle-stimulating hormone promotes renal tubulointerstitial fibrosis in aging women via the AKT/GSK-3β/β-catenin pathway. Aging Cell. 2019;18:e12997 pubmed publisher |
| Su M, Wang P, Wang X, Zhang M, Wei S, Liu K, et al. Nuclear CD44 Mediated by Importin β Participated in Naïve Genes Transcriptional Regulation in C3A-iCSCs. Int J Biol Sci. 2019;15:1252-1260 pubmed publisher |
| Xing Y, Zhang Z, Chi F, Zhou Y, Ren S, Zhao Z, et al. AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-κB pathway. Mol Carcinog. 2019;58:1795-1808 pubmed publisher |
| Xu B, Lang L, Li S, Guo J, Wang J, Wang D, et al. Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure. Cells. 2019;8: pubmed publisher |
| Mu F, Huang J, Xing T, Jing Y, Cui T, Guo Y, et al. The Wnt/β-Catenin/LEF1 Pathway Promotes Cell Proliferation at Least in Part Through Direct Upregulation of miR-17-92 Cluster. Front Genet. 2019;10:525 pubmed publisher |
| Wang Z, Chen Z, Jiang Z, Luo P, Liu L, Huang Y, et al. Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents. Nat Commun. 2019;10:2538 pubmed publisher |
| Li A, Shen T, Wang T, Zhou M, Wang B, Song J, et al. Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis. Free Radic Biol Med. 2019;141:21-33 pubmed publisher |
| Xu X, Wang D, Zheng C, Gao B, Fan J, Cheng P, et al. Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane. Theranostics. 2019;9:2252-2267 pubmed publisher |
| Wang Q, Hu J, Liu Y, Li J, Liu B, Li M, et al. Aerobic Exercise Improves Synaptic-Related Proteins of Diabetic Rats by Inhibiting FOXO1/NF-κB/NLRP3 Inflammatory Signaling Pathway and Ameliorating PI3K/Akt Insulin Signaling Pathway. J Mol Neurosci. 2019;: pubmed publisher |
| Yan Y, Qin D, Hu B, Zhang C, Liu S, Wu D, et al. Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis. Mol Ther Nucleic Acids. 2019;16:494-504 pubmed publisher |
| Zhao K, Jia Y, Peng J, Pang C, Zhang T, Han W, et al. Anacardic acid inhibits RANKL-induced osteoclastogenesis in vitro and prevents ovariectomy-induced bone loss in vivo. FASEB J. 2019;:fj201802575RR pubmed publisher |
| Park J, Lee Y, Lee D, Bae S. Repositioning of niclosamide ethanolamine (NEN), an anthelmintic drug, for the treatment of lipotoxicity. Free Radic Biol Med. 2019;137:143-157 pubmed publisher |
| Zhou X, Li W, Wang S, Zhang P, Wang Q, Xiao J, et al. YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis. Cell Rep. 2019;27:1176-1189.e5 pubmed publisher |
| Sikura K, Potor L, Szerafin T, Oros M, Nagy P, Mehes G, et al. Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease. Br J Pharmacol. 2019;: pubmed publisher |
| Jia Y, Peng Y, Zhao Y, Cheng X, Zhou Y, Chai C, et al. Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs. J Agric Food Chem. 2019;: pubmed publisher |
| Liu Y, Deng J, Fan D. Ginsenoside Rk3 ameliorates high-fat-diet/streptozocin induced type 2 diabetes mellitus in mice via the AMPK/Akt signaling pathway. Food Funct. 2019;10:2538-2551 pubmed publisher |
| Liu J, Cui Y, Shi L, Luan J, Zhou X, Han J. A cellular model for Wilson's disease using patient-derived induced pluripotent stem cells revealed aberrant β-catenin pathway during osteogenesis. Biochem Biophys Res Commun. 2019;513:386-391 pubmed publisher |
| Chen M, Peng C, Maner R, Zulkefli N, Huang S, Hsieh C. Geniposide ameliorated fluoxetine-suppressed neurite outgrowth in Neuro2a neuroblastoma cells. Life Sci. 2019;226:1-11 pubmed publisher |
| Zhu Y, Shao Y, Qu X, Guo J, Yang J, Zhou Z, et al. Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway. Biochem Biophys Res Commun. 2019;512:793-798 pubmed publisher |
| Li J, Liu Y, Liu B, Li F, Hu J, Wang Q, et al. Mechanisms of Aerobic Exercise Upregulating the Expression of Hippocampal Synaptic Plasticity-Associated Proteins in Diabetic Rats. Neural Plast. 2019;2019:7920540 pubmed publisher |
| Xu X, Liu Q, Zhang C, Ren S, Xu L, Zhao Z, et al. Inhibition of DYRK1A-EGFR axis by p53-MDM2 cascade mediates the induction of cellular senescence. Cell Death Dis. 2019;10:282 pubmed publisher |
| Park J, Lee D, Lee Y, Oh E, Bae K, Oh K, et al. Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity. Autophagy. 2019;:1-20 pubmed publisher |
| Zhang C, Li C, Jia X, Wang K, Tu Y, Wang R, et al. In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways. Molecules. 2019;24: pubmed publisher |
| Palikhe S, Ohashi W, Sakamoto T, Hattori K, Kawakami M, Andoh T, et al. Regulatory Role of GRK2 in the TLR Signaling-Mediated iNOS Induction Pathway in Microglial Cells. Front Pharmacol. 2019;10:59 pubmed publisher |
| Li Y, Feng D, Wang Z, Zhao Y, Sun R, Tian D, et al. Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion. Cell Death Differ. 2019;: pubmed publisher |
| Trajkovic K, Valdez C, Ysselstein D, Krainc D. Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes. PLoS ONE. 2019;14:e0211727 pubmed publisher |
| Li M, Wang S, Li X, Kou R, Wang Q, Wang X, et al. Diallyl sulfide treatment protects against acetaminophen-/carbon tetrachloride-induced acute liver injury by inhibiting oxidative stress, inflammation and apoptosis in mice. Toxicol Res (Camb). 2019;8:67-76 pubmed publisher |
| Feng W, Wang J, Yan X, Zhai C, Shi W, Wang Q, et al. Paclitaxel alleviates monocrotaline-induced pulmonary arterial hypertension via inhibition of FoxO1-mediated autophagy. Naunyn Schmiedebergs Arch Pharmacol. 2019;392:605-613 pubmed publisher |
| Liu Y, Zhang X, Zhou S, Shi J, Xu Y, He J, et al. Knockdown of Golgi phosphoprotein 73 blocks the trafficking of matrix metalloproteinase-2 in hepatocellular carcinoma cells and inhibits cell invasion. J Cell Mol Med. 2019;23:2399-2409 pubmed publisher |
| Liu Y, Wang X, Pang J, Zhang H, Luo J, Qian X, et al. Attenuation of Atherosclerosis by Protocatechuic Acid via Inhibition of M1 and Promotion of M2 Macrophage Polarization. J Agric Food Chem. 2019;67:807-818 pubmed publisher |
| Lei P, Tian S, Teng C, Huang L, Liu X, Wang J, et al. Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro. Mol Nutr Food Res. 2019;63:e1800795 pubmed publisher |
| Li B, Cao Y, Meng G, Qian L, Xu T, Yan C, et al. Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway. EBioMedicine. 2019;39:239-254 pubmed publisher |
| Trendel J, Schwarzl T, Horos R, Prakash A, Bateman A, Hentze M, et al. The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest. Cell. 2019;176:391-403.e19 pubmed publisher |
| Shan H, Li T, Zhang L, Yang R, Li Y, Zhang M, et al. Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence. EBioMedicine. 2019;39:59-68 pubmed publisher |
| Qi S, Zhang P, Ma M, Yao M, Wu J, Mäkilä E, et al. Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells. Small. 2019;15:e1804332 pubmed publisher |
| Han M, Zhao M, Cheng C, Huang Y, Han S, Li W, et al. Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation. Hum Mutat. 2019;40:310-325 pubmed publisher |
| Xu L, Liu J, Li K, Wang S, Xu S. Genistein inhibits Ang II-induced CRP and MMP-9 generations via the ER-p38/ERK1/2-PPARγ-NF-κB signaling pathway in rat vascular smooth muscle cells. Life Sci. 2019;216:140-146 pubmed publisher |
| Liu Y, Xue X, Zhang H, Che X, Luo J, Wang P, et al. Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia. Autophagy. 2019;15:493-509 pubmed publisher |
| Jin Q, Martinez C, Arcipowski K, Zhu Y, Gutiérrez Díaz B, Wang K, et al. USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia. Clin Cancer Res. 2019;25:222-239 pubmed publisher |
| Zhang Y, Chen Y, Zheng J, Wang J, Duan S, Zhang W, et al. Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat. J Mol Cell Biol. 2019;11:383-394 pubmed publisher |
| Li Q, Li Z, Sun S, Wang L, Wang P, Guo Z, et al. PARP1 interacts with HMGB1 and promotes its nuclear export in pathological myocardial hypertrophy. Acta Pharmacol Sin. 2019;40:589-598 pubmed publisher |
| Di X, He G, Chen H, Zhu C, Qin Q, Yan J, et al. High-mobility group box 1 protein modulated proliferation and radioresistance in esophageal squamous cell carcinoma. J Gastroenterol Hepatol. 2019;34:728-735 pubmed publisher |
| Tian Y, Chen K, Zulkefli N, Maner R, Hsieh C. Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells. Molecules. 2018;23: pubmed publisher |
| Li Y, Zhang Z, Chen J, Liu W, Lai W, Liu B, et al. Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1. Nature. 2018;564:136-140 pubmed publisher |
| He H, Lin K, Su Y, Lin S, Zou C, Pan J, et al. Overexpression of β-Catenin Decreases the Radiosensitivity of Human Nasopharyngeal Carcinoma CNE-2 Cells. Cell Physiol Biochem. 2018;50:1929-1944 pubmed publisher |
| Li Y, Chen Y, Qiu C, Ma X, Lei K, Cai G, et al. 17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death. J Cell Biochem. 2018;: pubmed publisher |
| Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X. Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro. Med Sci Monit. 2018;24:7654-7664 pubmed publisher |
| Liu Z, Dong W, Yang B, Peng L, Xia X, Pu L, et al. Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis. Chem Res Toxicol. 2018;31:1230-1239 pubmed publisher |
| Bai H, Zhu H, Yan Q, Shen X, Lu X, Wang J, et al. TRPV2-induced Ca2+-calcineurin-NFAT signaling regulates differentiation of osteoclast in multiple myeloma. Cell Commun Signal. 2018;16:68 pubmed publisher |
| Yoney A, Etoc F, Ruzo A, Carroll T, Metzger J, Martyn I, et al. WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids. elife. 2018;7: pubmed publisher |
| Lellahi S, Rosenlund I, Hedberg A, Kiær L, Mikkola I, Knutsen E, et al. The long noncoding RNA NEAT1 and nuclear paraspeckles are up-regulated by the transcription factor HSF1 in the heat shock response. J Biol Chem. 2018;293:18965-18976 pubmed publisher |
| Zhang L, Zhang J, Zhang Y, Wang L, Fei C, Yi Z, et al. Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway. Biochem Biophys Res Commun. 2018;505:837-842 pubmed publisher |
| Alsousi A, Igwe O. Redox-active trace metal-induced release of high mobility group box 1(HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like receptor 4 (TLR4) dependent. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3847-3858 pubmed publisher |
| Liu P, Chen B, Gu Y, Liu Q. PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway. Biomed Pharmacother. 2018;108:492-499 pubmed publisher |
| Liu L, Shen Y, Zhu X, Lv R, Li S, Zhang Z, et al. ERα is a negative regulator of PD-L1 gene transcription in breast cancer. Biochem Biophys Res Commun. 2018;505:157-161 pubmed publisher |
| Zhu Q, Lin X, Liu X, Hou T, Zhang M, Wang N, et al. Dynamic changes of proteasome and protective effect of bortezomib, a proteasome inhibitor, in mice with acute pancreatitis. Biochem Biophys Res Commun. 2018;505:126-133 pubmed publisher |
| Li Y, Li G, Zhou M, Xiang L, Ren D, Lou H, et al. Discovery of natural flavonoids as activators of Nrf2-mediated defense system: Structure-activity relationship and inhibition of intracellular oxidative insults. Bioorg Med Chem. 2018;26:5140-5150 pubmed publisher |
| Shi W, Zhai C, Feng W, Wang J, Zhu Y, Li S, et al. Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation. Life Sci. 2018;210:140-149 pubmed publisher |
| Liu L, Pan Y, Zhai C, Zhu Y, Ke R, Shi W, et al. Activation of peroxisome proliferation-activated receptor-γ inhibits transforming growth factor-β1-induced airway smooth muscle cell proliferation by suppressing Smad-miR-21 signaling. J Cell Physiol. 2018;234:669-681 pubmed publisher |
| Fang X, Liu Y, Lu J, Hong H, Yuan J, Zhang Y, et al. Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2018;391:1373-1385 pubmed publisher |
| Li L, Huang W, Wang S, Sun K, Zhang W, Ding Y, et al. Astragaloside IV Attenuates Acetaminophen-Induced Liver Injuries in Mice by Activating the Nrf2 Signaling Pathway. Molecules. 2018;23: pubmed publisher |
| Hu M, Liu L, Yao W. Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells. Gene. 2018;678:261-269 pubmed publisher |
| Wang Y, Wang Y, Liu Z, Dong W, Yang B, Xia X, et al. Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling. Chem Res Toxicol. 2018;31:954-963 pubmed publisher |
| Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, et al. Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo. J Cell Physiol. 2018;234:777-788 pubmed publisher |
| Zhang X, Li X, Fang J, Hou X, Fang H, Guo F, et al. (2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating. J Cell Biochem. 2018;119:8981-8995 pubmed publisher |
| Ning C, Gao X, Wang C, Kong Y, Liu Z, Sun H, et al. Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro. Regul Toxicol Pharmacol. 2018;98:58-68 pubmed publisher |
| Sun Y, Chen H, Dai J, Wan Z, Xiong P, Xu Y, et al. Glycyrrhizin Protects Mice Against Experimental Autoimmune Encephalomyelitis by Inhibiting High-Mobility Group Box 1 (HMGB1) Expression and Neuronal HMGB1 Release. Front Immunol. 2018;9:1518 pubmed publisher |
| Zhai C, Shi W, Feng W, Zhu Y, Wang J, Li S, et al. Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-?B-mediated autophagy activation. Life Sci. 2018;208:87-95 pubmed publisher |
| Zhang Y, Li A, Shi J, Fang Y, Gu C, Cai J, et al. Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting ?-catenin nuclear translocation. Cell Death Dis. 2018;9:749 pubmed publisher |
| Wu C, Jiang X, Wang X, Liu X, Li X, Yang B, et al. Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus. J Virol. 2018;92: pubmed publisher |
| Nguyen A, Guedán A, Mousnier A, Swieboda D, Zhang Q, Horkai D, et al. Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets. J Lipid Res. 2018;59:1671-1684 pubmed publisher |
| Yan X, Lu J, Zou X, Zhang S, Cui Y, Zhou L, et al. The polypeptide N-acetylgalactosaminyltransferase 4 exhibits stage-dependent expression in colorectal cancer and affects tumorigenesis, invasion and differentiation. FEBS J. 2018;285:3041-3055 pubmed publisher |
| Sun T, Wang F, Pan W, Wu Q, Wang J, Dai J. An Immunosuppressive Tick Salivary Gland Protein DsCystatin Interferes With Toll-Like Receptor Signaling by Downregulating TRAF6. Front Immunol. 2018;9:1245 pubmed publisher |
| Galarza Torre A, Shaw J, Wood A, Gilbert H, Dobre O, Genever P, et al. An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness. Sci Rep. 2018;8:8981 pubmed publisher |
| Chen X, Wu L, Li D, Xu Y, Zhang L, Niu K, et al. Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1?. Cancer Med. 2018;7:3834-3847 pubmed publisher |
| Liu X, Zhu Q, Zhang M, Yin T, Xu R, Xiao W, et al. Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway. Oxid Med Cell Longev. 2018;2018:7161592 pubmed publisher |
| Cui S, Men L, Li Y, Zhong Y, Yu S, Li F, et al. Selenoprotein S Attenuates Tumor Necrosis Factor-?-Induced Dysfunction in Endothelial Cells. Mediators Inflamm. 2018;2018:1625414 pubmed publisher |
| Ke M, Dong J, Wang Y, Zhang J, Zhang M, Wu Z, et al. MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells. Int J Biochem Cell Biol. 2018;101:39-48 pubmed publisher |
| Wang R, Li C, Qiao P, Xue Y, Zheng X, Chen H, et al. OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos. Cell Death Dis. 2018;9:628 pubmed publisher |
| Wang Y, Yan S, Xiao B, Zuo S, Zhang Q, Chen G, et al. Prostaglandin F2? Facilitates Hepatic Glucose Production Through CaMKII?/p38/FOXO1 Signaling Pathway in Fasting and Obesity. Diabetes. 2018;67:1748-1760 pubmed publisher |
| Shi X, Zhao Y, Ding C, Wang Z, Ji A, Li Z, et al. Salvianolic acid A alleviates chronic ethanol-induced liver injury via promotion of β-catenin nuclear accumulation by restoring SIRT1 in rats. Toxicol Appl Pharmacol. 2018;350:21-31 pubmed publisher |
| Wang H, Chen Y, Guo J, Shan T, Deng K, Chen J, et al. Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1. Sci Rep. 2018;8:7080 pubmed publisher |
| Yang M, Huang W, Yang F, Zhang T, Wang C, Song Y. Fam83h mutation inhibits the mineralization in ameloblasts by activating Wnt/?-catenin signaling pathway. Biochem Biophys Res Commun. 2018;501:206-211 pubmed publisher |
| Tao L, Li D, Liu H, Jiang F, Xu Y, Cao Y, et al. Neuroprotective effects of metformin on traumatic brain injury in rats associated with NF-κB and MAPK signaling pathway. Brain Res Bull. 2018;140:154-161 pubmed publisher |
| Ma J, Zhen X, Huang X, Jiang X. Folic acid supplementation repressed hypoxia-induced inflammatory response via ROS and JAK2/STAT3 pathway in human promyelomonocytic cells. Nutr Res. 2018;53:40-50 pubmed publisher |
| Otkur W, Liu W, Wang J, Jia X, Huang D, Wang F, et al. Sub-lethal ultraviolet B irradiation and Poly I:C treatment synergistically induced apoptosis of HaCaT cells through NF-κB pathway. Mol Immunol. 2018;99:19-29 pubmed publisher |
| Harada A, Maehara K, Ono Y, Taguchi H, Yoshioka K, Kitajima Y, et al. Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration. Nat Commun. 2018;9:1400 pubmed publisher |
| Li F, Liu B, Cai M, Li J, Lou S. Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise. Brain Res Bull. 2018;140:52-59 pubmed publisher |
| Li C, Xu L, Jian L, Yu R, Zhao J, Sun L, et al. Stattic inhibits RANKL-mediated osteoclastogenesis by suppressing activation of STAT3 and NF-κB pathways. Int Immunopharmacol. 2018;58:136-144 pubmed publisher |
| Kai W, Yating S, Lin M, Kaiyong Y, Baojin H, Wu Y, et al. Natural product toosendanin reverses the resistance of human breast cancer cells to adriamycin as a novel PI3K inhibitor. Biochem Pharmacol. 2018;152:153-164 pubmed publisher |
| Zhang S, Xie C, Li H, Zhang K, Li J, Wang X, et al. Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma. Lab Invest. 2018;98:883-894 pubmed publisher |
| Pariollaud M, Gibbs J, Hopwood T, Brown S, Begley N, Vonslow R, et al. Circadian clock component REV-ERB? controls homeostatic regulation of pulmonary inflammation. J Clin Invest. 2018;128:2281-2296 pubmed publisher |
| Hong F, Wan L, Liu J, Huang K, Xiao Z, Zhang Y, et al. Histone methylation regulates Hif-1 signaling cascade in activation of hepatic stellate cells. FEBS Open Bio. 2018;8:406-415 pubmed publisher |
| Wu H, He M, Yang R, Zuo Y, Bian Z. Astrocyte elevated gene-1 participates in the production of pro-inflammatory cytokines in dental pulp cells via NF-κB signalling pathway. Int Endod J. 2018;51:1130-1138 pubmed publisher |
| Wang L, Li Z, Tan Y, Li Q, Yang H, Wang P, et al. PARP1 interacts with STAT3 and retains active phosphorylated-STAT3 in nucleus during pathological myocardial hypertrophy. Mol Cell Endocrinol. 2018;474:137-150 pubmed publisher |
| Xu Q, Cui Y, Luan J, Zhou X, Li H, Han J. Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p. Biochem Biophys Res Commun. 2018;498:32-37 pubmed publisher |
| Pan X, Li D, Huo J, Kong F, Yang H, Ma X. LINC01016 promotes the malignant phenotype of endometrial cancer cells by regulating the miR-302a-3p/miR-3130-3p/NFYA/SATB1 axis. Cell Death Dis. 2018;9:303 pubmed publisher |
| Li T, Yi L, Hai L, Ma H, Tao Z, Zhang C, et al. The interactome and spatial redistribution feature of Ca2+ receptor protein calmodulin reveals a novel role in invadopodia-mediated invasion. Cell Death Dis. 2018;9:292 pubmed publisher |
| Qi X, Guo Y, Song Y, Yu C, Zhao L, Fang L, et al. Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice. Diabetologia. 2018;61:1180-1192 pubmed publisher |
| Shen Z, Ma Y, Ji Z, Hao Y, Yan X, Zhong Y, et al. Arachidonic acid induces macrophage cell cycle arrest through the JNK signaling pathway. Lipids Health Dis. 2018;17:26 pubmed publisher |
| Jia Y, Lu H, Peng Y, Zhang B, Gong X, Su J, et al. Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice. Int Immunopharmacol. 2018;56:105-112 pubmed publisher |
| Yang Y, Qi Q, Wang Y, Shi Y, Yang W, Cen Y, et al. Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling. FASEB J. 2018;32:3096-3107 pubmed publisher |
| Sang Y, Li Y, Song L, Alvarez A, Zhang W, Lv D, et al. TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3. Cancer Res. 2018;78:1792-1804 pubmed publisher |
| Tian S, Li B, Lei P, Yang X, Zhang X, Bao Y, et al. Sulforaphane Improves Abnormal Lipid Metabolism via Both ERS-Dependent XBP1/ACC &SCD1 and ERS-Independent SREBP/FAS Pathways. Mol Nutr Food Res. 2018;62:e1700737 pubmed publisher |
| Luo W, Zhang J, Liang L, Wang G, Li Q, Zhu P, et al. Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication. PLoS Pathog. 2018;14:e1006851 pubmed publisher |
| Li X, Li X, Liang J, Cai X, Tao Q, Li Y, et al. IRF1 up-regulates isg15 gene expression in dsRNA stimulation or CSFV infection by targeting nucleotides -487 to -325 in the 5' flanking region. Mol Immunol. 2018;94:153-165 pubmed publisher |
| Han X, Liu C, Zhang K, Guo M, Shen Z, Liu Y, et al. Calpain and JNK pathways participate in isoflurane - induced nucleus translocation of apoptosis-inducing factor in the brain of neonatal rats. Toxicol Lett. 2018;285:60-73 pubmed publisher |
| Shi A, Shi H, Wang Y, Liu X, Cheng Y, Li H, et al. Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury. Int Immunopharmacol. 2018;54:125-130 pubmed publisher |
| Liu M, Xu H, Zhang L, Zhang C, Yang L, Ma E, et al. Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2. Biochem Biophys Res Commun. 2018;495:325-331 pubmed publisher |
| Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, et al. PTEN-L promotes type I interferon responses and antiviral immunity. Cell Mol Immunol. 2018;15:48-57 pubmed publisher |
| Hou Y, Wang Y, He Q, Li L, Xie H, Zhao Y, et al. Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury. Behav Brain Res. 2018;336:32-39 pubmed publisher |
| Jiang L, Xia T, Hu Y, Sun M, Yan S, Lei C, et al. IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3. Cell Mol Immunol. 2018;15:858-867 pubmed publisher |
| Wei X, Ye J, Shang Y, Chen H, Liu S, Liu L, et al. Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells. Oncotarget. 2017;8:109301-109318 pubmed publisher |
| Xu S, Liu J, Shi J, Wang Z, Ji L. 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2. Sci Rep. 2017;7:16511 pubmed publisher |
| Zhao J, Zhu J, Lv X, Xing J, Liu S, Chen C, et al. Curcumin potentiates the potent antitumor activity of ACNU against glioblastoma by suppressing the PI3K/AKT and NF-?B/COX-2 signaling pathways. Onco Targets Ther. 2017;10:5471-5482 pubmed publisher |
| Wu X, Zhu H, Yan J, Khan M, Yu X. Santamarine Inhibits NF-κB Activation and Induces Mitochondrial Apoptosis in A549 Lung Adenocarcinoma Cells via Oxidative Stress. Biomed Res Int. 2017;2017:4734127 pubmed publisher |
| Yan S, Wei X, Xu S, Sun H, Wang W, Liu L, et al. 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway. Oncotarget. 2017;8:80909-80922 pubmed publisher |
| Xie J, Long X, Gao L, Chen S, Zhao K, Li W, et al. Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity. J Infect Dis. 2017;217:35-46 pubmed publisher |
| Ghouili F, Martin L. Cooperative regulation of Gja1 expression by members of the AP-1 family cJun and cFos in TM3 Leydig and TM4 Sertoli cells. Gene. 2017;635:24-32 pubmed publisher |
| Li F, Zhu Y, Wan Y, Xie X, Ke R, Zhai C, et al. Activation of PPAR? inhibits HDAC1-mediated pulmonary arterial smooth muscle cell proliferation and its potential mechanisms. Eur J Pharmacol. 2017;814:324-334 pubmed publisher |
| Shrestha S, Zhu J, Wang Q, Du X, Liu F, Jiang J, et al. Melatonin potentiates the antitumor effect of curcumin by inhibiting IKK?/NF-?B/COX-2 signaling pathway. Int J Oncol. 2017;51:1249-1260 pubmed publisher |
| Bai J, Yu X, Liu K, Wang F, Jing G, Li H, et al. Central administration of tert-butylhydroquinone attenuates hypertension via regulating Nrf2 signaling in the hypothalamic paraventricular nucleus of hypertensive rats. Toxicol Appl Pharmacol. 2017;333:100-109 pubmed publisher |
| Lu Y, Xie S, Zhang W, Zhang C, Gao C, Sun Q, et al. Twa1/Gid8 is a ?-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis. Cell Res. 2017;27:1422-1440 pubmed publisher |
| Yang W, Sun Z, Yang B, Wang Q. Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays. Int J Mol Sci. 2017;18: pubmed publisher |
| Ye J, Wei X, Shang Y, Pan Q, Yang M, Tian Y, et al. Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity. Oncogene. 2017;36:6391-6407 pubmed publisher |
| Chen F, Su X, Lin Z, Lin Y, Yu L, Cai J, et al. Necrostatin-1 attenuates early brain injury after subarachnoid hemorrhage in rats by inhibiting necroptosis. Neuropsychiatr Dis Treat. 2017;13:1771-1782 pubmed publisher |
| Li S, Pan Y, Ke R, Xie X, Zhai C, Shi W, et al. Inhibition of phosphodiesterase-5 suppresses calcineurin/NFAT- mediated TRPC6 expression in pulmonary artery smooth muscle cells. Sci Rep. 2017;7:6088 pubmed publisher |
| Wang J, Yu Z, Wang C, Tian X, Huo X, Wang Y, et al. Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-?B/COX-2 signaling pathway by targeting IKK?. Am J Cancer Res. 2017;7:1270-1284 pubmed |
| Su C, Liu Z, Wang Y, Wang Y, Song E, Song Y. The electrophilic character of quinones is essential for the suppression of Bach1. Toxicology. 2017;387:17-26 pubmed publisher |
| Song Z, Yang W, Zhou X, Yang L, Zhao D. Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling. Neuropharmacology. 2017;123:332-348 pubmed publisher |
| Song Z, Shah S, Yang W, Dong H, Yang L, Zhou X, et al. Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-?-Catenin Signaling in Prion Diseases Models. Front Mol Neurosci. 2017;10:128 pubmed publisher |
| Chen X, Zhao X, Cai H, Sun H, Hu Y, Huang X, et al. The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways. Redox Biol. 2017;12:987-1003 pubmed publisher |
| Ma L, Sun P, Zhang J, Zhang Q, Yao S. Proinflammatory effects of S100A8/A9 via TLR4 and RAGE signaling pathways in BV-2 microglial cells. Int J Mol Med. 2017;40:31-38 pubmed publisher |
| Fang W, Bi D, Zheng R, Cai N, Xu H, Zhou R, et al. Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages. Sci Rep. 2017;7:1663 pubmed publisher |
| Xie X, Li S, Zhu Y, Liu L, Pan Y, Wang J, et al. MicroRNA-27a/b mediates endothelin-1-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells. Cell Tissue Res. 2017;369:527-539 pubmed publisher |
| Huang W, Zhou W, Li C, Yang Y, Shang Y, Chen C, et al. Promoter mutations and cellular distribution of telomerase in non-clear cell and clear cell hepatocellular carcinoma. Oncotarget. 2017;8:26288-26297 pubmed publisher |
| Gasset Rosa F, Chillon Marinas C, Goginashvili A, Atwal R, Artates J, Tabet R, et al. Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport. Neuron. 2017;94:48-57.e4 pubmed publisher |
| Qin C, Ren L, Ji M, Lv S, Wei Y, Zhu D, et al. CDKL1 promotes tumor proliferation and invasion in colorectal cancer. Onco Targets Ther. 2017;10:1613-1624 pubmed publisher |
| Zhang X, Fu L, Xue D, Zhang X, Hao F, Xie L, et al. Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer. Virchows Arch. 2017;470:553-560 pubmed publisher |
| Gong X, Yang Y, Huang L, Zhang Q, Wan R, Zhang P, et al. Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice. Int Immunopharmacol. 2017;46:124-132 pubmed publisher |
| Chen D, Tang J, Wan Q, Zhang J, Wang K, Shen Y, et al. E-Prostanoid 3 Receptor Mediates Sprouting Angiogenesis Through Suppression of the Protein Kinase A/?-Catenin/Notch Pathway. Arterioscler Thromb Vasc Biol. 2017;37:856-866 pubmed publisher |
| Fu J, Xia X, Liu Z, Wang Y, Wang Y, Shi Q, et al. The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning. Toxicology. 2017;381:39-50 pubmed publisher |
| Guedán A, Swieboda D, Charles M, Toussaint M, Johnston S, Asfor A, et al. Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication. J Virol. 2017;91: pubmed publisher |
| Tian Y, Li Z, Shen B, Zhang Q, Feng H. Protective effects of morin on lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting TLR4/NF-?B and activating Nrf2/HO-1 signaling pathways. Int Immunopharmacol. 2017;45:148-155 pubmed publisher |
| Qu J, Sun W, Zhong J, Lv H, Zhu M, Xu J, et al. Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells. J Cell Biol. 2017;216:409-424 pubmed publisher |
| Xie Q, Fan F, Wei W, Liu Y, Xu Z, Zhai L, et al. Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells. Sci Rep. 2017;7:41089 pubmed publisher |
| You L, Liu H, Huang J, Xie W, Wei J, Ye X, et al. The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins. Oncotarget. 2017;8:7777-7790 pubmed publisher |
| Song X, Shi Q, Liu Z, Wang Y, Wang Y, Song E, et al. Unpredicted Downregulation of RAD51 Suggests Genome Instability Induced by Tetrachlorobenzoquinone. Chem Res Toxicol. 2016;29:2184-2193 pubmed |
| Ly P, Teitz L, Kim D, Shoshani O, Skaletsky H, Fachinetti D, et al. Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining. Nat Cell Biol. 2017;19:68-75 pubmed publisher |
| Guo J, Wu Y, Yang L, Du J, Gong K, Chen W, et al. Repression of YAP by NCTD disrupts NSCLC progression. Oncotarget. 2017;8:2307-2319 pubmed publisher |
| Hu Y, Ma H, Zou Z, He K, Xiao Y, Wang Y, et al. Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress. Biomed Pharmacother. 2017;85:313-322 pubmed publisher |
| Ren X, Li X, Jia L, Chen D, Hou H, Rui L, et al. A small-molecule inhibitor of NF-?B-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury. FASEB J. 2017;31:711-718 pubmed publisher |
| Zhong H, Xiao M, Zarkovic K, Zhu M, Sa R, Lu J, et al. Mitochondrial control of apoptosis through modulation of cardiolipin oxidation in hepatocellular carcinoma: A novel link between oxidative stress and cancer. Free Radic Biol Med. 2017;102:67-76 pubmed publisher |
| Yan T, Yu X, Sun X, Meng D, Jia J. A new steroidal saponin, furotrilliumoside from Trillium tschonoskii inhibits lipopolysaccharide-induced inflammation in Raw264.7 cells by targeting PI3K/Akt, MARK and Nrf2/HO-1 pathways. Fitoterapia. 2016;115:37-45 pubmed publisher |
| Lee D, Han D, Nam K, Park J, Kim S, Lee M, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016;99:520-532 pubmed publisher |
| Zhang L, Xin Q, Zhu S, Wan W, Wang W, Xiao G. Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus. J Virol. 2016;90:10259-10270 pubmed publisher |
| Lai D, Gao J, Bi X, He H, Shi X, Weng S, et al. The Rho kinase inhibitor, fasudil, ameliorates diabetes-induced cardiac dysfunction by improving calcium clearance and actin remodeling. J Mol Med (Berl). 2017;95:155-165 pubmed publisher |
| Nie H, Xue X, Liu G, Guan G, Liu H, Sun L, et al. Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase. Free Radic Res. 2016;50:1200-1213 pubmed |
| Jin M, Yu B, Zhang W, Zhang W, Xiao Z, Mao Z, et al. Toll-like receptor 2-mediated MAPKs and NF-?B activation requires the GNAO1-dependent pathway in human mast cells. Integr Biol (Camb). 2016;8:968-75 pubmed publisher |
| Kuan M, O Dowd J, Fortunato E. The absence of p53 during Human Cytomegalovirus infection leads to decreased UL53 expression, disrupting UL50 localization to the inner nuclear membrane, and thereby inhibiting capsid nuclear egress. Virology. 2016;497:262-278 pubmed publisher |
| Tome M, Herndon J, Schaefer C, Jacobs L, Zhang Y, Jarvis C, et al. P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain. J Cereb Blood Flow Metab. 2016;36:1913-1928 pubmed |
| Gama Sosa M, De Gasperi R, Hof P, Elder G. Fibroblast growth factor rescues brain endothelial cells lacking presenilin 1 from apoptotic cell death following serum starvation. Sci Rep. 2016;6:30267 pubmed publisher |
| Tao X, Sun X, Xu L, Yin L, Han X, Qi Y, et al. Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats. Nutrients. 2016;8: pubmed publisher |
| Su C, Shi Q, Song X, Fu J, Liu Z, Wang Y, et al. Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling. Toxicology. 2016;363-364:48-57 pubmed publisher |
| Shao W, Machamer C, Espenshade P. Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner. J Lipid Res. 2016;57:1564-73 pubmed publisher |
| Chen L, Hu M, Xu Z, Liu Y, Shu H. MSX1 Modulates RLR-Mediated Innate Antiviral Signaling by Facilitating Assembly of TBK1-Associated Complexes. J Immunol. 2016;197:199-207 pubmed publisher |
| Dong L, Li Y, An H, Wang Y, Chen S, Qian Y, et al. The E3 Ubiquitin Ligase c-Cbl Inhibits Microglia-Mediated CNS Inflammation by Regulating PI3K/Akt/NF-?B Pathway. CNS Neurosci Ther. 2016;22:661-9 pubmed publisher |
| Wu J, Lu M, Li Y, Shang Y, Wang S, Meng Y, et al. Regulation of a TGF-β1-CD147 self-sustaining network in the differentiation plasticity of hepatocellular carcinoma cells. Oncogene. 2016;35:5468-5479 pubmed publisher |
| Yu Y, Huang Z, Mao Z, Zhang Y, Jin M, Chen W, et al. Go is required for the release of IL-8 and TNF-?, but not degranulation in human mast cells. Eur J Pharmacol. 2016;780:115-21 pubmed publisher |
| Shi H, Shi A, Dong L, Lu X, Wang Y, Zhao J, et al. Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress. Clin Nutr. 2016;35:1366-1373 pubmed publisher |
| Nie Y, Wang M, Zhang P, Huan L, Liu D. Identification and characterization of an endoplasmic reticulum localization motif. Biochem Biophys Res Commun. 2016;473:249-254 pubmed publisher |
| Huang X, He Z, Jiang X, Hou M, Tang Z, Zhen X, et al. Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α Pathway. PLoS ONE. 2016;11:e0151553 pubmed publisher |
| Wang G, Yao J, Li Z, Zu G, Feng D, Shan W, et al. miR-34a-5p Inhibition Alleviates Intestinal Ischemia/Reperfusion-Induced Reactive Oxygen Species Accumulation and Apoptosis via Activation of SIRT1 Signaling. Antioxid Redox Signal. 2016;24:961-73 pubmed publisher |
| Song Z, Zhu T, Zhou X, Barrow P, Yang W, Cui Y, et al. REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling. Oncotarget. 2016;7:12035-52 pubmed publisher |
| He W, Ye X, Huang X, Lel W, You L, Wang L, et al. Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells. Int J Oncol. 2016;48:1710-20 pubmed publisher |
| Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, et al. AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation. Aging Cell. 2016;15:416-27 pubmed publisher |
| Zhang J, Huang F, Tan L, Bai C, Chen B, Liu J, et al. Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein. J Virol. 2016;90:3966-3980 pubmed publisher |
| Li H, Cui Y, Luan J, Zhang X, Li C, Zhou X, et al. PRELP (proline/arginine-rich end leucine-rich repeat protein) promotes osteoblastic differentiation of preosteoblastic MC3T3-E1 cells by regulating the β-catenin pathway. Biochem Biophys Res Commun. 2016;470:558-562 pubmed publisher |
| Gesson K, Rescheneder P, Skoruppa M, von Haeseler A, Dechat T, Foisner R. A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha. Genome Res. 2016;26:462-73 pubmed publisher |
| Fu J, Shi Q, Song X, Xia X, Su C, Liu Z, et al. Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling. Environ Toxicol Pharmacol. 2016;41:241-50 pubmed publisher |
| Li S, Zhu M, Pan R, Fang T, Cao Y, Chen S, et al. The tumor suppressor PTEN has a critical role in antiviral innate immunity. Nat Immunol. 2016;17:241-9 pubmed publisher |
| Shiau J, Yin S, Chang S, Hsu Y, Chen K, Kuo T, et al. Mechanistic Study of the Phytocompound, 2- β -D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches. Evid Based Complement Alternat Med. 2015;2015:475610 pubmed publisher |
| Shi Q, Song X, Fu J, Su C, Xia X, Song E, et al. Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice. Int Immunopharmacol. 2015;29:722-729 pubmed publisher |
| He K, Tong D, Zhang S, Cai D, Wang L, Yang Y, et al. miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells. Int J Oncol. 2015;47:1528-36 pubmed publisher |
| Jin X, Liu Y, Liu J, Lu W, Liang Z, Zhang D, et al. The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo. PLoS ONE. 2015;10:e0133770 pubmed publisher |
| Hu Q, Yang C, Wang Q, Zeng H, Qin W. Demethylzeylasteral (T-96) Treatment Ameliorates Mice Lupus Nephritis Accompanied by Inhibiting Activation of NF-κB Pathway. PLoS ONE. 2015;10:e0133724 pubmed publisher |
| Zhu M, Fang T, Li S, Meng K, Guo D. Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3. J Immunol. 2015;195:289-97 pubmed publisher |
| Su C, Xia X, Shi Q, Song X, Fu J, Xiao C, et al. Neohesperidin Dihydrochalcone versus CClâ‚„-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation. J Agric Food Chem. 2015;63:5468-75 pubmed publisher |
| Liu S, Jing F, Yu C, Gao L, Qin Y, Zhao J. AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver. PLoS ONE. 2015;10:e0124951 pubmed publisher |
| Qin L, Yin Y, Zheng F, Peng L, Yang C, Bao Y, et al. WNT5A promotes stemness characteristics in nasopharyngeal carcinoma cells leading to metastasis and tumorigenesis. Oncotarget. 2015;6:10239-52 pubmed |
| Gao N, He H, Xiao L, Gao X, Shi H, Wu Q, et al. The effects of focal adhesion kinase on the motility, proliferation and apoptosis of Caco2 and SMMC-7721 cells. Med Oncol. 2015;32:125 pubmed publisher |
| Hu Y, Duan M, Liang S, Wang Y, Feng Y. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3. Brain Res. 2015;1605:39-48 pubmed publisher |
| Wang F, Yang J, Yu K, Xu M, Xu Y, Chen L, et al. Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma. Mol Cancer. 2015;14:10 pubmed publisher |
| Mao Q, Xie Z, Wang X, Chen W, Ren M, Shang M, et al. Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells. Parasitol Res. 2015;114:659-70 pubmed publisher |
