This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
IMPDH2
catalog :
12948-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:500; loading ...; fig 1b
  • western blot; human; loading ...; fig s2
Calise S, Purich D, Nguyen T, Saleem D, Krueger C, Yin J, et al. 'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway. J Cell Sci. 2016;129:3042-52 pubmed publisher
Ali E, Sahu U, Villa E, O Hara B, Gao P, Beaudet C, et al. ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis. Mol Cell. 2020;78:1178-1191.e6 pubmed publisher
Zheng P, Li L. FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway. Onco Targets Ther. 2020;13:451-463 pubmed publisher
Keppeke G, Barcelos D, Fernandes M, Comodo A, Guimarães D, Cardili L, et al. IMP dehydrogenase rod/ring structures in acral melanomas. Pigment Cell Melanoma Res. 2019;: pubmed publisher
Keppeke G, Calise S, Chan E, Andrade L. Ribavirin induces widespread accumulation of IMP dehydrogenase into rods/rings structures in multiple major mouse organs. Antiviral Res. 2019;162:130-135 pubmed publisher
Calise S, Abboud G, Kasahara H, Morel L, Chan E. Immune Response-Dependent Assembly of IMP Dehydrogenase Filaments. Front Immunol. 2018;9:2789 pubmed publisher
Chang C, Keppeke G, Sung L, Liu J. Interfilament interaction between IMPDH and CTPS cytoophidia. FEBS J. 2018;285:3753-3768 pubmed publisher
Keppeke G, Chang C, Peng M, Chen L, Lin W, Pai L, et al. IMP/GTP balance modulates cytoophidium assembly and IMPDH activity. Cell Div. 2018;13:5 pubmed publisher
Keppeke G, Prado M, Nunes E, Perazzio S, Rodrigues S, Ferraz M, et al. Differential capacity of therapeutic drugs to induce Rods/Rings structures in vitro and in vivo and generation of anti-Rods/Rings autoantibodies. Clin Immunol. 2016;173:149-156 pubmed publisher
Keppeke G, Calise S, Chan E, Andrade L. Assembly of IMPDH2-based, CTPS-based, and mixed rod/ring structures is dependent on cell type and conditions of induction. J Genet Genomics. 2015;42:287-99 pubmed publisher
Keppeke G, Andrade L, Grieshaber S, Chan E. Microinjection of specific anti-IMPDH2 antibodies induces disassembly of cytoplasmic rods/rings that are primarily stationary and stable structures. Cell Biosci. 2015;5:1 pubmed publisher
product information
CatalogNo :
12948-1-AP
AntigenName :
IMPDH2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
IMP (inosine monophosphate) dehydrogenase 2
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
IMP dehydrogenase 2, IMPD 2, IMPD2, IMPDH 2, IMPDH II, IMPDH2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC012840
Category :
Binding Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:50 ; IP 1:800 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.