This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
BACE1
catalog :
12807-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 12
Reference
Barrett T, Marchalant Y, Park K. p35 Hemizygous Deletion in 5xFAD Mice Increases Aβ Plaque Load in Males but Not in Females. Neuroscience. 2019;417:45-56 pubmed publisher
Inoue Y, Ueda M, Masuda T, Misumi Y, Yamashita T, Ando Y. Memantine, a Noncompetitive N-Methyl-D-Aspartate Receptor Antagonist, Attenuates Cerebral Amyloid Angiopathy by Increasing Insulin-Degrading Enzyme Expression. Mol Neurobiol. 2019;: pubmed publisher
Liu J, Zhang W, Wang S, Jia Z, Shi Y, Yang L, et al. Effects of chain length of saturated fatty acids on Aβ generation in SH-SY5Y cells. Neurosci Lett. 2019;698:169-172 pubmed publisher
Zhang Y, Xie J, Xu X, Hu J, Xu T, Jin S, et al. Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting. Neurosci Bull. 2019;: pubmed publisher
Hu W, Feng Z, Xu J, Jiang Z, Feng M. Brain-derived neurotrophic factor modified human umbilical cord mesenchymal stem cells-derived cholinergic-like neurons improve spatial learning and memory ability in Alzheimer's disease rats. Brain Res. 2019;1710:61-73 pubmed publisher
Yang Q, Lin J, Zhang H, Liu Y, Kan M, Xiu Z, et al. Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments. J Mol Neurosci. 2019;67:62-71 pubmed publisher
Shentu Y, Huo Y, Feng X, Gilbert J, Zhang Q, Liuyang Z, et al. CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer's Disease. Cell Rep. 2018;24:713-723 pubmed publisher
Zhao Y, Zhang L, Yu P, Gou Y, Zhao J, You L, et al. Ceruloplasmin, a Potential Therapeutic Agent for Alzheimer's Disease. Antioxid Redox Signal. 2018;28:1323-1337 pubmed publisher
Hou H, Fan Q, He W, Suh H, Hu X, Yan R. BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus. Stem Cell Reports. 2017;9:217-230 pubmed publisher
Wang X, Liu D, Liang Y, Xing L, Zhao W, Qin X, et al. Cystatin C Shifts APP Processing from Amyloid-? Production towards Non-Amyloidgenic Pathway in Brain Endothelial Cells. PLoS ONE. 2016;11:e0161093 pubmed publisher
Zhang Y, Yang X, Jin G, Yang X, Zhang Y. Polysaccharides from Pleurotus ostreatus alleviate cognitive impairment in a rat model of Alzheimer's disease. Int J Biol Macromol. 2016;92:935-941 pubmed publisher
Hayakawa M, Itoh M, Ohta K, Li S, Ueda M, Wang M, et al. Quercetin reduces eIF2α phosphorylation by GADD34 induction. Neurobiol Aging. 2015;36:2509-18 pubmed publisher
product information
CatalogNo :
12807-1-AP
AntigenName :
BACE1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
beta-site APP-cleaving enzyme 1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Asp 2, ASP2, Aspartyl protease 2, BACE, BACE1, Beta secretase 1, HSPC104, KIAA1149, Memapsin 2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC036084
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Neurology;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:200 ; IP 1:500 ; WB 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.