FAK | Proteintech Group 12636-1-AP product information

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product summary

company name :

Proteintech Group

product type :

antibody

product name :

FAK

catalog :

12636-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 25

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 5	Alekhina O, Marchese A. ?-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4. J Biol Chem. 2016;291:26083-26097 pubmed
	Wu X, Bian F, Hu H, Zhu T, Li C, Zhou Q. Effects of Kindlin-2 on proliferation and migration of VSMC and integrinβ1 andβ3 activity via FAK-PI3K signaling pathway. PLoS ONE. 2020;15:e0225173 pubmed publisher
	Wang Y, Guo Q, Hei H, Tao J, Zhou Y, Dong J, et al. BK ablation attenuates osteoblast bone formation via integrin pathway. Cell Death Dis. 2019;10:738 pubmed publisher
	Cao D, Qi Z, Pang Y, Li H, Xie H, Wu J, et al. Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer. Cancer Res. 2019;79:2604-2618 pubmed publisher
	Zheng D, Chang X, Liu Y, Xu J, Gou W, Li Z, et al. 2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines. Cancer Biol Ther. 2019;20:513-523 pubmed publisher
	Liu S, Xu C, Wu W, Fu Z, He S, Qin M, et al. Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis. Int J Oncol. 2019;54:41-52 pubmed publisher
	Ai W, Dong L, Wang J, Li Z, Wang X, Gao J, et al. Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3780-3791 pubmed publisher
	Yu M, Li W, Wang Q, Wang Y, Lu F. Circadian regulator NR1D2 regulates glioblastoma cell proliferation and motility. Oncogene. 2018;37:4838-4853 pubmed publisher
	Liu J, Shuang Y, Li C, Zhou X, Huang Y, Zhang L. Expression of DCUN1D1 in laryngeal squamous cell carcinoma and its inhibiting effect on TU-177 cells after interfered by RNA. Clin Exp Pharmacol Physiol. 2018;45:461-466 pubmed publisher
	Wu B, Zhang L, Zhu Y, Zhang Y, Zheng F, Yang J, et al. Mesoderm/mesenchyme homeobox gene l promotes vascular smooth muscle cell phenotypic modulation and vascular remodeling. Int J Cardiol. 2018;251:82-89 pubmed publisher
	Zhang Y, Huang Y, Huang T, Pang W, Zhu J, LIU Y, et al. The Mammalian Target of Rapamycin and DNA methyltransferase 1 axis mediates vascular endothelial dysfunction in response to disturbed flow. Sci Rep. 2017;7:14996 pubmed publisher
	Yin L, Qi Y, Xu Y, Xu L, Han X, Tao X, et al. Dioscin Inhibits HSC-T6 Cell Migration via Adjusting SDC-4 Expression: Insights from iTRAQ-Based Quantitative Proteomics. Front Pharmacol. 2017;8:665 pubmed publisher
	Pan X, Zhang R, Xie C, Gan M, Yao S, Yao Y, et al. GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer. Am J Transl Res. 2017;9:4217-4226 pubmed
	Li X, Zhou X, Chen Y, Yu S, Chen X, Xia X, et al. Surface changes of nanotopography by carbon ion implantation to enhance the biocompatibility of silicone rubber: an in vitro study of the optimum ion fluence and adsorbed protein. J Mater Sci Mater Med. 2017;28:167 pubmed publisher
	Baba K, Kitajima Y, Miyake S, Nakamura J, Wakiyama K, Sato H, et al. Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines. Sci Rep. 2017;7:11127 pubmed publisher
	Luo H, Li Z, Ge H, Mei D, Zhao L, Jiang L, et al. HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice. Chem Biol Interact. 2017;277:1-7 pubmed publisher
	Xu L, Yin L, Tao X, Qi Y, Han X, Xu Y, et al. Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis. Food Chem Toxicol. 2017;107:318-328 pubmed publisher
	Zhang H, Ma R, Wang X, Su Z, Chen X, Shi D, et al. KIF26B, a novel oncogene, promotes proliferation and metastasis by activating the VEGF pathway in gastric cancer. Oncogene. 2017;36:5609-5619 pubmed publisher
	Xu C, Liu S, Qin M, Zhuge C, Qin L, Qin N, et al. SphK1 modulates cell migration and EMT-related marker expression by regulating the expression of p-FAK in colorectal cancer cells. Int J Mol Med. 2017;39:1277-1284 pubmed publisher
	Li Y, Wu Z, Yuan J, Sun L, Lin L, Huang N, et al. Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis. Cancer Lett. 2017;395:31-44 pubmed publisher
	Yin K, Zhu R, Wang S, Zhao R. Low-Level Laser Effect on Proliferation, Migration, and Antiapoptosis of Mesenchymal Stem Cells. Stem Cells Dev. 2017;26:762-775 pubmed publisher
	Lin C, Li X, Luo Q, Yang H, Li L, Zhou Q, et al. RELM-Î² promotes human pulmonary artery smooth muscle cell proliferation via FAK-stimulated surviving. Exp Cell Res. 2017;351:43-50 pubmed publisher
	Xie Y, Wang J, Zhang Y, Liu X, Wang X, Liu K, et al. Quantitative profiling of spreading-coupled protein tyrosine phosphorylation in migratory cells. Sci Rep. 2016;6:31811 pubmed publisher
	Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, et al. DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway. Med Oncol. 2015;32:115 pubmed publisher
	Liu C, Liu Y, Xu X, Wu H, Xie H, Chen L, et al. Potential effect of matrix stiffness on the enrichment of tumor initiating cells under three-dimensional culture conditions. Exp Cell Res. 2015;330:123-34 pubmed publisher

product information

CatalogNo :

12636-1-AP

AntigenName :

FAK

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

PTK2 protein tyrosine kinase 2

Immunogen :

Recombinant Protein

Species :

human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, IF, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

FADK, FADK 1, FAK, FAK1, Focal adhesion kinase 1, pp125FAK, Protein tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC028733

Category :

Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Disease Related;Immunology;Membrane Proteins;Metabolism;Senescence;Signal transduction;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

IF 1:50 ; IHC 1:100 ; IP 1:2000 ; WB 1:1000 ;