Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; fig 6
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| Li Y, Yang J, Zhang X, Liu H, Guo J. KDM6A suppresses hepatocellular carcinoma cell proliferation by negatively regulating the TGF-β/SMAD signaling pathway. Exp Ther Med. 2020;20:2774-2782 pubmed publisher
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| Zheng S, Wan L, Ge D, Jiang F, Qian Z, Tang J, et al. LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma. Cell Death Dis. 2020;11:576 pubmed publisher
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| Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, et al. WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling. Oxid Med Cell Longev. 2020;2020:7950457 pubmed publisher
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| Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, et al. Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression. Biomed Pharmacother. 2020;127:110132 pubmed publisher
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| Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, et al. TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis. J Cell Mol Med. 2020;24:5224-5237 pubmed publisher
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| Shao Q, Jiang C, Xia Y, Zhao M, Zhang Q, Jin B, et al. Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway. Int J Clin Exp Pathol. 2019;12:867-875 pubmed
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| Tran B, Yu Y, Chang L, Tan B, Jia W, Xiong Y, et al. A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway. Int J Nanomedicine. 2019;14:10061-10077 pubmed publisher
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| Zhou X, Xiong J, Lu S, Luo L, Chen Z, Yang F, et al. Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway. Am J Chin Med. 2019;47:1541-1569 pubmed publisher
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| Fan P, Li Z, Zuo C, Fang M. Promotion effects of mono-2-ethyhexyl phthalate (MEHP) on migration and invasion of human melanoma cells via activation of TGF-β signals. Cell Biochem Funct. 2019;: pubmed publisher
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| Lei R, Li J, Liu F, Li W, Zhang S, Wang Y, et al. HIF-1α promotes the keloid development through the activation of TGF-β/Smad and TLR4/MyD88/NF-κB pathways. Cell Cycle. 2019;18:3239-3250 pubmed publisher
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| Jin J, Sun H, Liu D, Wang H, Liu Q, Chen H, et al. LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury. Neuroscience. 2019;: pubmed publisher
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| Yuan J, Tan L, Yin Z, Zhu W, Tao K, Wang G, et al. MIR17HG-miR-18a/19a axis, regulated by interferon regulatory factor-1, promotes gastric cancer metastasis via Wnt/β-catenin signalling. Cell Death Dis. 2019;10:454 pubmed publisher
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| Xue K, Zhang J, Li C, Li J, Wang C, Zhang Q, et al. The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis. J Cell Mol Med. 2019;23:4229-4243 pubmed publisher
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| Hu B, Mao Z, Du Q, Jiang X, Wang Z, Xiao Z, et al. miR-93-5p targets Smad7 to regulate the transforming growth factor-β1/Smad3 pathway and mediate fibrosis in drug-resistant prolactinoma. Brain Res Bull. 2019;149:21-31 pubmed publisher
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| Guo Y, Cui W, Pei Y, Xu D. Platelets promote invasion and induce epithelial to mesenchymal transition in ovarian cancer cells by TGF-β signaling pathway. Gynecol Oncol. 2019;153:639-650 pubmed publisher
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| Xie H, Su D, Zhang J, Ji D, Mao J, Hao M, et al. Raw and vinegar processed Curcuma wenyujin regulates hepatic fibrosis via bloking TGF-β/Smad signaling pathways and up-regulation of MMP-2/TIMP-1 ratio. J Ethnopharmacol. 2019;: pubmed publisher
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| Zhao J, Meng M, Zhang J, Li L, Zhu X, Zhang L, et al. Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction. Mol Med Rep. 2019;19:3168-3178 pubmed publisher
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| Lewis D, Pruitt H, Jain N, Ciccaglione M, McCaffery J, Xia Z, et al. A Feedback Loop between Hypoxia and Matrix Stress Relaxation Increases Oxygen-Axis Migration and Metastasis in Sarcoma. Cancer Res. 2019;79:1981-1995 pubmed publisher
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| Wang B, Xu X, Yang Z, Zhang L, Liu Y, Ma A, et al. POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1. EBioMedicine. 2019;41:320-332 pubmed publisher
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| He W, Liang B, Wang C, Li S, Zhao Y, Huang Q, et al. MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer. Oncogene. 2019;38:4637-4654 pubmed publisher
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| Yan L, You W, Sheng N, Gong J, Hu L, Tan G, et al. A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer. Aging (Albany NY). 2018;10:3774-3793 pubmed publisher
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| Ye X, He L, Ma J, Li Y, Zhang M, Yang J, et al. Downregulation of Glt25d1 aggravates carbon tetrachloride‑induced acute hepatic injury through activation of the TGF‑β1/Smad2 signaling pathway. Mol Med Rep. 2018;18:3611-3618 pubmed publisher
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| Hu B, Mao Z, Jiang X, He D, Wang Z, Wang X, et al. Role of TGF-β1/Smad3-mediated fibrosis in drug resistance mechanism of prolactinoma. Brain Res. 2018;1698:204-212 pubmed publisher
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| Lu H, Wu L, Liu L, Ruan Q, Zhang X, Hong W, et al. Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization. Biochem Pharmacol. 2018;154:203-212 pubmed publisher
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| Deng W, Gao M, Lei X, Lv J, Zhao H, He K, et al. Gene Correction Reverses Ciliopathy and Photoreceptor Loss in iPSC-Derived Retinal Organoids from Retinitis Pigmentosa Patients. Stem Cell Reports. 2018;10:1267-1281 pubmed publisher
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| Li J, Zou K, Yu L, Zhao W, Lu Y, Mao J, et al. MicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer. Mol Ther Nucleic Acids. 2018;10:426-437 pubmed publisher
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| Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q. PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis. Cell Death Dis. 2018;9:307 pubmed publisher
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| Wang E, Fan Q, Yue Y, Xu L. Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway. Med Sci Monit. 2018;24:846-854 pubmed
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| Xiao Y, Ye J, Zhou Y, Huang J, Liu X, Huang B, et al. Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-?/Smads signaling pathway. Arch Biochem Biophys. 2018;640:37-46 pubmed publisher
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| Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z. CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-?B/ iNOS pathway in STZ-induced diabetic mice. Oncotarget. 2017;8:114506-114525 pubmed publisher
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| Zhao B, Liu L, Mao J, Liu K, Fan W, Liu J, et al. Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro. Biomed Pharmacother. 2017;96:1036-1044 pubmed publisher
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| Cai Y, Ma W, Xiao Y, Wu B, Li X, Liu F, et al. High doses of baicalin induces kidney injury and fibrosis through regulating TGF-?/Smad signaling pathway. Toxicol Appl Pharmacol. 2017;333:1-9 pubmed publisher
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| Lei K, Liang X, Gao Y, Xu B, Xu Y, Li Y, et al. Lnc-ATB contributes to gastric cancer growth through a MiR-141-3p/TGF?2 feedback loop. Biochem Biophys Res Commun. 2017;484:514-521 pubmed publisher
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| Zhang X, Fan Q, Li Y, Yang Z, Yang L, Zong Z, et al. Transforming growth factor-beta1 suppresses hepatocellular carcinoma proliferation via activation of Hippo signaling. Oncotarget. 2017;8:29785-29794 pubmed publisher
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| Xiang J, Fu X, Ran W, Wang Z. Grhl2 reduces invasion and migration through inhibition of TGF?-induced EMT in gastric cancer. Oncogenesis. 2017;6:e284 pubmed publisher
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| Zhuang X, Lv M, Zhong Z, Zhang L, Jiang R, Chen J. Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways. J Exp Clin Cancer Res. 2016;35:130 pubmed publisher
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| Yan N, Wen L, Peng R, Li H, Liu H, Peng H, et al. Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy. J Diabetes Res. 2016;2016:8738760 pubmed publisher
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| You S, Ma L, Zhao J, Zhang S, Liu T. Phenylethanol Glycosides from Cistanche tubulosa Suppress Hepatic Stellate Cell Activation and Block the Conduction of Signaling Pathways in TGF-β1/smad as Potential Anti-Hepatic Fibrosis Agents. Molecules. 2016;21:102 pubmed publisher
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| Zhang X, Xiao J, Li R, Qin X, Wang F, Mao Y, et al. Metformin alleviates vascular calcification induced by vitamin D3 plus nicotine in rats via the AMPK pathway. Vascul Pharmacol. 2016;81:83-90 pubmed publisher
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| Dong D, Yin L, Qi Y, Xu L, Peng J. Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats. Nutrients. 2015;7:4829-50 pubmed publisher
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| Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, et al. Potent effects of dioscin against liver fibrosis. Sci Rep. 2015;5:9713 pubmed publisher
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| Chen M, Zhang J, Wang J, Gao L, Chen X, Xiao J. Anti-fibrotic effects of neferine on carbon tetrachloride-induced hepatic fibrosis in mice. Am J Chin Med. 2015;43:231-40 pubmed publisher
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