This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
IDH1
catalog :
12332-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, western blot knockout validation
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; loading ...; fig s4j
Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed publisher
  • western blot; human; loading ...; fig 5g
Zhu Z, Li C, Zeng Y, Ding J, Qu Z, Gu J, et al. PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs. Cell Stem Cell. 2017;20:274-289.e7 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 5i
Liu L, Shah S, Fan J, Park J, Wellen K, Rabinowitz J. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nat Chem Biol. 2016;12:345-52 pubmed publisher
  • western blot; human; tbl 1
Richarson A, Scott D, Zagnitko O, Aza Blanc P, Chang C, Russler Germain D. Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation. elife. 2016;5:e10860 pubmed publisher
Sellers K, Allen T, Bousamra M, Tan J, Méndez Lucas A, Lin W, et al. Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes. Br J Cancer. 2019;: pubmed publisher
Liu L, Li T, Song G, He Q, Yin Y, Lu J, et al. Insight into novel RNA-binding activities via large-scale analysis of lncRNA-bound proteome and IDH1-bound transcriptome. Nucleic Acids Res. 2019;: pubmed publisher
White K, Kim M, Han C, Park H, Ding D, Boyd K, et al. Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice. Sci Rep. 2018;8:5039 pubmed publisher
Xiang S, Gu H, Jin L, Thorne R, Zhang X, Wu M. LncRNA IDH1-AS1 links the functions of c-Myc and HIF1? via IDH1 to regulate the Warburg effect. Proc Natl Acad Sci U S A. 2018;115:E1465-E1474 pubmed publisher
Zang S, Tang Q, Dong F, Liu H, Li L, Guo F, et al. Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1. Oncol Rep. 2017;38:3583-3591 pubmed publisher
Liu D, Zheng X, Zho Y, Yi W, Li Z, Hu X, et al. HIF-1? inhibits IDH-1 expression in osteosarcoma. Oncol Rep. 2017;38:336-342 pubmed publisher
White K, Kim M, Ding D, Han C, Park H, Meneses Z, et al. G6pd Deficiency Does Not Affect the Cytosolic Glutathione or Thioredoxin Antioxidant Defense in Mouse Cochlea. J Neurosci. 2017;37:5770-5781 pubmed publisher
Intlekofer A, Wang B, Liu H, Shah H, Carmona Fontaine C, Rustenburg A, et al. L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH. Nat Chem Biol. 2017;13:494-500 pubmed publisher
Chen X, Li Q, Wang C, Xu W, Han L, Liu Y, et al. Prognostic and diagnostic potential of isocitrate dehydrogenase 1 in esophageal squamous cell carcinoma. Oncotarget. 2016;7:86148-86160 pubmed publisher
Chen K, Zhang J, Guo Z, Ma Q, Xu Z, Zhou Y, et al. Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer. Cell Res. 2016;26:103-18 pubmed publisher
Huang L, Zou Y, Weng H, Li H, Liu J, Yang W. Proteomic profile in Perna viridis after exposed to Prorocentrum lima, a dinoflagellate producing DSP toxins. Environ Pollut. 2015;196:350-7 pubmed
product information
CatalogNo :
12332-1-AP
AntigenName :
IDH1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
isocitrate dehydrogenase 1 (NADP+), soluble
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
IDCD, IDH, IDH1, IDP, IDPC, NADP(+) specific ICDH, Oxalosuccinate decarboxylase, PICD
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC012846
Category :
Binding Proteins;Disease Related;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:25 ; IHC 1:50 ; IP 1:600 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.