This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
OXCT1
catalog :
12175-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:10,000; loading ...; fig 1b
Major J, Dewan A, Salih M, Leddy J, Tuana B. E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy. PLoS ONE. 2017;12:e0170066 pubmed publisher
Dai J, Jiang L, Qiu L, Shao Y, Shi P, Li J. WHSC1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Activating mTORC1 Signaling. Onco Targets Ther. 2020;13:7033-7044 pubmed publisher
Monsálves Álvarez M, Morales P, Castro Sepúlveda M, Sepúlveda C, Rodriguez J, Chiong M, et al. β-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle. Nutrients. 2020;12: pubmed publisher
Goldberg E, Molony R, Kudo E, Sidorov S, Kong Y, Dixit V, et al. Ketogenic diet activates protective γδ T cell responses against influenza virus infection. Sci Immunol. 2019;4: pubmed publisher
Zeng J, Zhou S, Zhao J, Jin M, Kang D, Yang Y, et al. Role of OXCT1 in ovine adipose and preadipocyte differentiation. Biochem Biophys Res Commun. 2019;512:779-785 pubmed publisher
Stumpf S, Berghoff S, Trevisiol A, Spieth L, Düking T, Schneider L, et al. Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease. Acta Neuropathol. 2019;138:147-161 pubmed publisher
Nishimura T, Nakata A, Chen X, Nishi K, Meguro Horike M, Sasaki S, et al. Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2. Oncogene. 2019;38:2464-2481 pubmed publisher
Puchalska P, Martin S, Huang X, Lengfeld J, Dániel B, Graham M, et al. Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis. Cell Metab. 2019;29:383-398.e7 pubmed publisher
Zhang J, Jia P, Liu Q, Cong M, Gao Y, Shi H, et al. Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo. J Lipid Res. 2018;59:625-634 pubmed publisher
Schatton D, Pla Martín D, Marx M, Hansen H, Mourier A, Nemazanyy I, et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017;216:675-693 pubmed publisher
Huang D, Li T, Wang L, Zhang L, Yan R, Li K, et al. Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress. Cell Res. 2016;26:1112-1130 pubmed publisher
Youm Y, Nguyen K, Grant R, Goldberg E, Bodogai M, Kim D, et al. The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Nat Med. 2015;21:263-9 pubmed publisher
product information
CatalogNo :
12175-1-AP
AntigenName :
OXCT1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
3-oxoacid CoA transferase 1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
3 oxoacid CoA transferase 1, OXCT, OXCT1, SCOT, SCOT s
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC009001
Category :
Cytoskeleton/Scaffold Proteins;Metabolism;Organelle Marker;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:200 ; IP 1:1000 ; WB 1:4000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.