This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
FKBP65
catalog :
12172-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 8
Reference
Ramadori G, Ioris R, Villanyi Z, Firnkes R, Panasenko O, Allen G, et al. FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth. Cell Rep. 2020;30:3851-3863.e6 pubmed publisher
Terajima M, Taga Y, Cabral W, Liu Y, Nagasawa M, Sumida N, et al. Cyclophilin B control of lysine post-translational modifications of skin type I collagen. PLoS Genet. 2019;15:e1008196 pubmed publisher
Ishikawa Y, Holden P, Bachinger H. Heat shock protein 47 and 65-kDa FK506-binding protein weakly but synergistically interact during collagen folding in the endoplasmic reticulum. J Biol Chem. 2017;292:17216-17224 pubmed publisher
Chen Y, Terajima M, Banerjee P, Guo H, Liu X, Yu J, et al. FKBP65-dependent peptidyl-prolyl isomerase activity potentiates the lysyl hydroxylase 2-driven collagen cross-link switch. Sci Rep. 2017;7:46021 pubmed publisher
Lietman C, Lim J, Grafe I, Chen Y, Ding H, Bi X, et al. Fkbp10 Deletion in Osteoblasts Leads to Qualitative Defects in Bone. J Bone Miner Res. 2017;32:1354-1367 pubmed publisher
Durán I, Martin J, Weis M, Krejci P, Konik P, Li B, et al. A Chaperone Complex Formed by HSP47, FKBP65, and BiP Modulates Telopeptide Lysyl Hydroxylation of Type I Procollagen. J Bone Miner Res. 2017;32:1309-1319 pubmed publisher
Gjaltema R, van der Stoel M, Boersema M, Bank R. Disentangling mechanisms involved in collagen pyridinoline cross-linking: The immunophilin FKBP65 is critical for dimerization of lysyl hydroxylase 2. Proc Natl Acad Sci U S A. 2016;113:7142-7 pubmed publisher
Durán I, Nevarez L, Sarukhanov A, Wu S, Lee K, Krejci P, et al. HSP47 and FKBP65 cooperate in the synthesis of type I procollagen. Hum Mol Genet. 2015;24:1918-28 pubmed publisher
product information
CatalogNo :
12172-1-AP
AntigenName :
FKBP65
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
FK506 binding protein 10, 65 kDa
Immunogen :
Recombinant Protein
Species :
chicken, human, mouse
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
65 kDa FK506 binding protein, 65 kDa FKBP, FK506 binding protein 10, FKBP 10, FKBP 65, FKBP10, FKBP6, FKBP65, hFKBP65, Immunophilin FKBP65, PPIase FKBP10, Rotamase
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC016467
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:600 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.