This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
PADI2
catalog :
12110-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 29
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig 3i
  • western blot; human; 1:1000; loading ...; fig 3g
Casanova V, Sousa F, Shakamuri P, Svoboda P, Buch C, D Acremont M, et al. Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection. Front Immunol. 2020;11:85 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s2a
Chaudhury A, Cheema S, Fachini J, Kongchan N, Lu G, Simon L, et al. CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT. Nat Commun. 2016;7:13362 pubmed publisher
  • western blot; human; fig 5c
Cantarino N, Fernández Figueras M, Valero V, Musulen E, Malinverni R, Granada I, et al. A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma. Int J Cancer. 2016;139:1106-16 pubmed publisher
Hamamoto Y, Ouhara K, Munenaga S, Shoji M, Ozawa T, Hisatsune J, et al. Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model. Arthritis Res Ther. 2020;22:249 pubmed publisher
Li F, Miao L, Xue T, Qin H, Mondal S, Thompson P, et al. Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells. J Exp Clin Cancer Res. 2019;38:414 pubmed publisher
Byrd A, Carmona Rivera C, O Neil L, Carlucci P, Cisar C, Rosenberg A, et al. Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa. Sci Transl Med. 2019;11: pubmed publisher
Song S, Xiang Z, Li J, Ji J, Yan R, Zhu Z, et al. A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein. Front Oncol. 2019;9:304 pubmed publisher
Falcão A, Meijer M, Scaglione A, Rinwa P, Agirre E, Liang J, et al. PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. Cell Rep. 2019;27:1090-1102.e10 pubmed publisher
Zhou Q, Song C, Liu X, Qin H, Miao L, Zhang X. Peptidylarginine deiminase 4 overexpression resensitizes MCF-7/ADR breast cancer cells to adriamycin via GSK3β/p53 activation. Cancer Manag Res. 2019;11:625-636 pubmed publisher
Sharma P, Lioutas A, Fernandez Fuentes N, Quilez J, Carbonell Caballero J, Wright R, et al. Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription. Mol Cell. 2019;73:84-96.e7 pubmed publisher
Liu Y, Lightfoot Y, Seto N, Carmona Rivera C, Moore E, Goel R, et al. Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus. JCI Insight. 2018;3: pubmed publisher
Hollingsworth T, Radic M, Beranova Giorgianni S, Giorgianni F, Wang Y, Iannaccone A. Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4). Invest Ophthalmol Vis Sci. 2018;59:3808-3815 pubmed publisher
Kim S, Park J, Kim M, Jang B, Jeon Y, Kim H, et al. Accumulation of citrullinated glial fibrillary acidic protein in a mouse model of bile duct ligation-induced hepatic fibrosis. PLoS ONE. 2018;13:e0201744 pubmed publisher
Zhao J, Duan X, Yang L, Liu J, He Y, Guo Z, et al. Activity-dependent Synaptic Recruitment of Neuroligin 1 in Spinal Dorsal Horn Contributed to Inflammatory Pain. Neuroscience. 2018;388:1-10 pubmed publisher
DeVore S, Young C, Li G, Sundararajan A, Ramaraj T, Mudge J, et al. Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells. Mol Cell Biol. 2018;38: pubmed publisher
Marre M, McGinty J, Chow I, DeNicola M, Beck N, Kent S, et al. Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes. Diabetes. 2018;67:1356-1368 pubmed publisher
Ledet M, Anderson R, Harman R, Muth A, Thompson P, Coonrod S, et al. BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway. BMC Cancer. 2018;18:412 pubmed publisher
Nemmara V, Subramanian V, Muth A, Mondal S, Salinger A, Maurais A, et al. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). ACS Chem Biol. 2018;13:712-722 pubmed publisher
Young C, Rothfuss H, Gard P, Muth A, Thompson P, Ashley R, et al. Citrullination regulates the expression of insulin-like growth factor-binding protein 1 (IGFBP1) in ovine uterine luminal epithelial cells. Reproduction. 2017;153:1-10 pubmed publisher
Chen D, Sun Q, Zhang L, Zhou X, Cheng X, Zhou D, et al. The lncRNA HOXA11-AS functions as a competing endogenous RNA to regulate PADI2 expression by sponging miR-125a-5p in liver metastasis of colorectal cancer. Oncotarget. 2017;8:70642-70652 pubmed publisher
Wang L, Song G, Zhang X, Feng T, Pan J, Chen W, et al. PADI2-Mediated Citrullination Promotes Prostate Cancer Progression. Cancer Res. 2017;77:5755-5768 pubmed publisher
Horibata S, Rogers K, Sadegh D, Anguish L, McElwee J, Shah P, et al. Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration. BMC Cancer. 2017;17:378 pubmed publisher
Funayama R, Taniguchi H, Mizuma M, Fujishima F, Kobayashi M, Ohnuma S, et al. Protein-arginine deiminase 2 suppresses proliferation of colon cancer cells through protein citrullination. Cancer Sci. 2017;108:713-718 pubmed publisher
Zhang X, Liu X, Zhang M, Li T, Muth A, Thompson P, et al. Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development. Sci Rep. 2016;6:38727 pubmed publisher
Khan S, Edwards B, Muth A, Thompson P, Cherrington B, Navratil A. GnRH Stimulates Peptidylarginine Deiminase Catalyzed Histone Citrullination in Gonadotrope Cells. Mol Endocrinol. 2016;30:1081-1091 pubmed
Cantarino N, Musulen E, Valero V, Peinado M, Perucho M, Moreno V, et al. Downregulation of the Deiminase PADI2 Is an Early Event in Colorectal Carcinogenesis and Indicates Poor Prognosis. Mol Cancer Res. 2016;14:841-8 pubmed publisher
Suzuki A, Kochi Y, Shoda H, Seri Y, Fujio K, Sawada T, et al. Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice. BMC Musculoskelet Disord. 2016;17:205 pubmed publisher
Okada Y, Muramatsu T, Suita N, Kanai M, Kawakami E, Iotchkova V, et al. Significant impact of miRNA-target gene networks on genetics of human complex traits. Sci Rep. 2016;6:22223 pubmed publisher
Lewallen D, Bicker K, Subramanian V, Clancy K, Slade D, Martell J, et al. Chemical Proteomic Platform To Identify Citrullinated Proteins. ACS Chem Biol. 2015;10:2520-8 pubmed publisher
product information
CatalogNo :
12110-1-AP
AntigenName :
PADI2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
peptidyl arginine deiminase, type II
Immunogen :
Recombinant Protein
Species :
dog, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, COIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
KIAA0994, PAD H19, PAD2, PADI2, PDI2, Peptidylarginine deiminase II
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC009701
Category :
Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:200 ; IP 1:300 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.