This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
KRAS
catalog :
12063-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 42
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; fig 5e
  • western blot; human; loading ...; fig 4c
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, et al. ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer. Mol Ther Oncolytics. 2019;14:299-312 pubmed publisher
  • western blot; mouse; fig 5c
Adams C, Htwe H, Marsh T, Wang A, Montoya M, Subbaraj L, et al. Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer. elife. 2019;8: pubmed publisher
Xiong X, Rao G, Roy R, Zhang Y, Means N, Dey A, et al. Ubiquitin-binding associated protein 2 regulates KRAS activation and macropinocytosis in pancreatic cancer. FASEB J. 2020;: pubmed publisher
Kumazaki M, Shimomura I, Kiyono T, Ochiya T, Yamamoto Y. Cell-type specific tumorigenesis with Ras oncogenes in human lung epithelial cells. Biochem Biophys Res Commun. 2020;525:483-490 pubmed publisher
Zhang X, Ma N, Yao W, Li S, Ren Z. RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer. Cancer Cell Int. 2019;19:356 pubmed publisher
Sale M, Minihane E, Monks N, Gilley R, Richards F, Schifferli K, et al. Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors. Nat Commun. 2019;10:5167 pubmed publisher
Che Y, Siprashvili Z, Kovalski J, Jiang T, Wozniak G, Elcavage L, et al. KRAS regulation by small non-coding RNAs and SNARE proteins. Nat Commun. 2019;10:5118 pubmed publisher
Chen S, Li D, Zhang H, Yu D, Chen R, Zhang B, et al. The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure. Environ Int. 2019;131:104943 pubmed publisher
Huang L, Wang Y, Chen J, Wang Y, Zhao Y, Wang Y, et al. Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma. Cell Death Dis. 2019;10:513 pubmed publisher
Zhang W, He P, Wang S, Adili A, Chen Z, Zhang C, et al. Characterization of Protein Profiling and mRNA Expression of LLC Exosomes. Protein J. 2019;: pubmed publisher
Ida K, Miyamoto T, Higuchi S, Takeuchi H, Yamada S, Ono M, et al. Effectiveness of a genetic test panel designed for gynecological cancer: an exploratory study. Med Oncol. 2019;36:62 pubmed publisher
Chen Y, Liu Z, Wang H, Tang Z, Liu Y, Liang Z, et al. VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer. Int J Cancer. 2019;: pubmed publisher
Zhao Y, Zhong S, Zhang S, Bi J, Xiao Z, Wang S, et al. UBN2 promotes tumor progression via the Ras/MAPK pathway and predicts poor prognosis in colorectal cancer. Cancer Cell Int. 2019;19:126 pubmed publisher
Chen Z, Yang D, Jiang X, Tian L, Sun J, Tian D, et al. Final-2 targeted glycolysis mediated apoptosis and autophagy in human lung adenocarcinoma cells but failed to inhibit xenograft in nude mice. Food Chem Toxicol. 2019;130:1-11 pubmed publisher
Gao L, Hu Y, Tian Y, Fan Z, Wang K, Li H, et al. Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition. Nat Commun. 2019;10:1665 pubmed publisher
Chen Z, Tian D, Liao X, Zhang Y, Xiao J, Chen W, et al. Apigenin Combined With Gefitinib Blocks Autophagy Flux and Induces Apoptotic Cell Death Through Inhibition of HIF-1α, c-Myc, p-EGFR, and Glucose Metabolism in EGFR L858R+T790M-Mutated H1975 Cells. Front Pharmacol. 2019;10:260 pubmed publisher
Xu H, Zhou S, Xia H, Yu H, Tang Q, Bi F. MEK nuclear localization promotes YAP stability via sequestering β-TrCP in KRAS mutant cancer cells. Cell Death Differ. 2019;: pubmed publisher
Mo X, Tang C, Niu Q, Ma T, Du Y, Fu H. HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers. Cell Chem Biol. 2019;26:331-339.e3 pubmed publisher
Dai X, Xia H, Zhou S, Tang Q, Bi F. Zoledronic acid enhances the efficacy of the MEK inhibitor trametinib in KRAS mutant cancers. Cancer Lett. 2018;442:202-212 pubmed publisher
Gao P, Wang X, Jin Y, Hu W, Duan Y, Shi A, et al. Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells. Breast Cancer Res. 2018;20:112 pubmed publisher
Du Z, Song X, Yan F, Wang J, Zhao Y, Liu S. Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells. Int J Oncol. 2018;: pubmed publisher
Akao Y, Kumazaki M, Shinohara H, Sugito N, Kuranaga Y, Tsujino T, et al. Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143. Cancer Sci. 2018;109:1455-1467 pubmed publisher
Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, et al. Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway. Cancer Lett. 2018;418:135-146 pubmed publisher
Chen M, Lin M, Wang X. Overexpression of miR-19a inhibits colorectal cancer angiogenesis by suppressing KRAS expression. Oncol Rep. 2018;39:619-626 pubmed publisher
Wang Y, Li J, Guo S, Ouyang Y, Yin L, Liu S, et al. Lin28B facilitates the progression and metastasis of pancreatic ductal adenocarcinoma. Oncotarget. 2017;8:60414-60428 pubmed publisher
Tsuboi M, Taniuchi K, Shimizu T, Saito M, Saibara T. The transcription factor HOXB7 regulates ERK kinase activity and thereby stimulates the motility and invasiveness of pancreatic cancer cells. J Biol Chem. 2017;292:17681-17702 pubmed publisher
Liu W, Zhang B, Hu Q, Qin Y, Xu W, Shi S, et al. A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism. Int J Oncol. 2017;50:1792-1800 pubmed publisher
Huang Y, Yang C, Wei P, Huynh T, Whang Peng J, Meng T, et al. Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways. J Hematol Oncol. 2017;10:60 pubmed publisher
Liang C, Qin Y, Zhang B, Ji S, Shi S, Xu W, et al. Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma. Mol Cancer Res. 2017;15:201-212 pubmed publisher
Kobayashi T, Nakazono K, Tokuda M, Mashima Y, Dynlacht B, Itoh H. HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma. EMBO Rep. 2017;18:334-343 pubmed publisher
Liang C, Qin Y, Zhang B, Ji S, Shi S, Xu W, et al. ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer. Cancer Lett. 2017;388:303-311 pubmed publisher
Wang Y, Chen Y, Liu S, Ye Y, Jiao H, Wang S, et al. MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42. Oncotarget. 2016;7:84826-84838 pubmed publisher
Song H, Biancucci M, Kang H, O Callaghan C, Park S, Principe D, et al. SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status. Oncotarget. 2016;7:80336-80349 pubmed publisher
Ye Y, Wu P, Gu C, Deng D, Jiao H, Li T, et al. miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression. Oncotarget. 2016;7:61312-61324 pubmed publisher
Wang S, Zhang W, Wu X, Zhang M, Weng M, Zhou D, et al. Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206. Oncotarget. 2016;7:37857-37867 pubmed publisher
Kim E, Ilic N, Shrestha Y, Zou L, Kamburov A, Zhu C, et al. Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles. Cancer Discov. 2016;6:714-26 pubmed publisher
Tanaka T, Ikegami Y, Nakazawa H, Kuriyama N, Oki M, Hanai J, et al. Low-Dose Farnesyltransferase Inhibitor Suppresses HIF-1? and Snail Expression in Triple-Negative Breast Cancer MDA-MB-231 Cells In Vitro. J Cell Physiol. 2017;232:192-201 pubmed publisher
Ramraj S, Aravindan S, Somasundaram D, Herman T, Natarajan M, Aravindan N. Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease. Oncotarget. 2016;7:18605-19 pubmed publisher
Ji H, Lee J, Wang Y, Pang Y, Zhang T, Xia Y, et al. EGFR phosphorylates FAM129B to promote Ras activation. Proc Natl Acad Sci U S A. 2016;113:644-9 pubmed publisher
Xu Q, Fu R, Yin G, Liu X, Liu Y, Xiang M. Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells. Gene. 2016;578:263-73 pubmed publisher
Chu P, Yang M, Kulp S, Salunke S, Himmel L, Fang C, et al. Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells. Oncogene. 2016;35:3897-908 pubmed publisher
Liu W, Ning R, Chen R, Huang X, Dai Q, Hu J, et al. Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells. Mol Carcinog. 2016;55:440-57 pubmed publisher
product information
CatalogNo :
12063-1-AP
AntigenName :
KRAS
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
C K RAS, c Ki ras, GTPase KRas, K Ras 2, K RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS, KRAS1, KRAS2, KRAS2A, KRAS2B, KRAS2B speicifc, Krasa, Krasb, NS3, RASK2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC013572
Category :
Binding Proteins;Cell Cycle;Disease Related;Membrane Proteins;Oncogene(s) and Tumor Suppressor(s);Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:800 ; IP 1:1000 ; WB 1:5000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.