This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
KLF4
catalog :
11880-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 40
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; 1:500; loading ...; fig 5d
  • immunoprecipitation; human; 1:500; loading ...; fig 5a
  • western blot; human; 1:500; loading ...; fig 5a
Zhu P, Wang Y, Wu J, Huang G, Liu B, Ye B, et al. LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells. Nat Commun. 2016;7:13608 pubmed publisher
Jiang Y, Gong H, Jiang S, She C, Cao Y. Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids. Sci Total Environ. 2020;748:141384 pubmed publisher
Wu B, Jiang M, Liu X, Huang C, Gu Z, Cao Y. Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo. Nanotoxicology. 2020;:1-22 pubmed publisher
Sun L, Lin P, Chen Y, Yu H, Ren S, Wang J, et al. miR-182-3p/Myadm contribute to pulmonary artery hypertension vascular remodeling via a KLF4/p21-dependent mechanism. Theranostics. 2020;10:5581-5599 pubmed publisher
Shi D, Shi X, Xing K, Zhou H, Lu L, Wu W. miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis. Cell Signal. 2020;72:109650 pubmed publisher
Ignatova V, Stolz P, Kaiser S, Gustafsson T, Lastres P, Sanz Moreno A, et al. The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs. Genes Dev. 2020;34:715-729 pubmed publisher
Mei Y, Cai D, Dai X. Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features. J Cancer. 2020;11:1162-1169 pubmed publisher
Sun Q, Gong L, Qi R, Qing W, Zou M, Ke Q, et al. Oxidative stress-induced KLF4 activates inflammatory response through IL17RA and its downstream targets in retinal pigment epithelial cells. Free Radic Biol Med. 2020;147:271-281 pubmed publisher
Wang W, Fu S, Lin X, Zheng J, Pu J, Gu Y, et al. miR-92b-3p Functions As A Key Gene In Esophageal Squamous Cell Cancer As Determined By Co-Expression Analysis. Onco Targets Ther. 2019;12:8339-8353 pubmed publisher
Zhang Y, Cui G, Wang Y, Gong Y, Wang Y. SIRT1 activation alleviates brain microvascular endothelial dysfunction in peroxisomal disorders. Int J Mol Med. 2019;44:995-1005 pubmed publisher
Tao H, Lin H, Sun Z, Pei F, Zhang J, Chen S, et al. Klf4 Promotes Dentinogenesis and Odontoblastic Differentiation via Modulation of TGF-β Signaling Pathway and Interaction With Histone Acetylation. J Bone Miner Res. 2019;: pubmed publisher
Yang H, Li J, Yang C, Liu H, Cao Y. Multi-walled carbon nanotubes promoted lipid accumulation in human aortic smooth muscle cells. Toxicol Appl Pharmacol. 2019;374:11-19 pubmed publisher
Sun Z, Yu S, Chen S, Liu H, Chen Z. SP1 regulates KLF4 via SP1 binding motif governed by DNA methylation during odontoblastic differentiation of human dental pulp cells. J Cell Biochem. 2019;: pubmed publisher
Zhu X, Du J, Yu J, Guo R, Feng Y, Qiao L, et al. LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop. J Mol Cell Cardiol. 2019;126:60-69 pubmed publisher
Chen W, Zhuo M, Lü X, Xia X, Zhao Y, Huang Z, et al. SRC-3 protects intestine from DSS-induced colitis by inhibiting inflammation and promoting goblet cell differentiation through enhancement of KLF4 expression. Int J Biol Sci. 2018;14:2051-2064 pubmed publisher
Li S, Xiao F, Zhang J, Sun X, Wang H, Zeng Y, et al. Disruption of OCT4 Ubiquitination Increases OCT4 Protein Stability and ASH2L-B-Mediated H3K4 Methylation Promoting Pluripotency Acquisition. Stem Cell Reports. 2018;11:973-987 pubmed publisher
Li Z, Jia Y, Han S, Wang X, Han F, Zhang J, et al. Klf4 Alleviates Lipopolysaccharide-Induced Inflammation by Inducing Expression of MCP-1 Induced Protein 1 to Deubiquitinate TRAF6. Cell Physiol Biochem. 2018;47:2278-2290 pubmed publisher
Li Z, Chen B, Weng X, Yu L, Song M, Fang M, et al. The histone methyltransferase SETD1A regulates thrombomodulin transcription in vascular endothelial cells. Biochim Biophys Acta Gene Regul Mech. 2018;1861:752-761 pubmed publisher
Li S, Lin C, Zhang J, Tao H, Liu H, Yuan G, et al. Quaking promotes the odontoblastic differentiation of human dental pulp stem cells. J Cell Physiol. 2018;233:7292-7304 pubmed publisher
Guo Y, Zeng Q, Liu S, Yu Q, Wang P, Ma H, et al. Generation of an iPS cell line via a non-integrative method using urine-derived cells from a patient with USH2A-associated retinitis pigmentosa. Stem Cell Res. 2018;29:139-142 pubmed publisher
Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, et al. Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice. Nat Commun. 2018;9:1261 pubmed publisher
Sun D, Li Q, Ding D, Li X, Xie M, Xu Y, et al. Role of Krüppel-like factor 4 in cigarette smoke-induced pulmonary vascular remodeling. Am J Transl Res. 2018;10:581-591 pubmed
Zhang X, Chen J, Sun L, Xu Y. SIRT1 deacetylates KLF4 to activate Claudin-5 transcription in ovarian cancer cells. J Cell Biochem. 2018;119:2418-2426 pubmed publisher
Dou D, Zhao H, Li Z, Xu L, Xiong X, Wu X, et al. CHD1L Promotes Neuronal Differentiation in Human Embryonic Stem Cells by Upregulating PAX6. Stem Cells Dev. 2017;26:1626-1636 pubmed publisher
Zhai F, Cao C, Zhang L, Zhang J. miR-543 promotes colorectal cancer proliferation and metastasis by targeting KLF4. Oncotarget. 2017;8:59246-59256 pubmed publisher
Zhuang J, Shen L, Yang L, Huang X, Lu Q, Cui Y, et al. TGF?1 Promotes Gemcitabine Resistance through Regulating the LncRNA-LET/NF90/miR-145 Signaling Axis in Bladder Cancer. Theranostics. 2017;7:3053-3067 pubmed publisher
Wang T, Chen K, Hsu P, Lin H, Wang Y, Chen C, et al. microRNA let-7g suppresses PDGF-induced conversion of vascular smooth muscle cell into the synthetic phenotype. J Cell Mol Med. 2017;21:3592-3601 pubmed publisher
Xu L, Sun H, Zhang M, Jiang Y, Zhang C, Zhou J, et al. MicroRNA-145 protects follicular granulosa cells against oxidative stress-induced apoptosis by targeting Krüppel-like factor 4. Mol Cell Endocrinol. 2017;452:138-147 pubmed publisher
Liu G, Zhou S, Ding X, Fang C, Mi S, Gao X, et al. Soluble expression of recomb inant cMyc, Klf4, Oct4, and Sox2 proteins in bacteria and transduction into living cells. Int J Ophthalmol. 2017;10:560-566 pubmed publisher
Zheng J, Liu Y, Qiao Y, Zhang L, Lu S. miR-103 Promotes Proliferation and Metastasis by Targeting KLF4 in Gastric Cancer. Int J Mol Sci. 2017;18: pubmed publisher
Minami K, Taniguchi K, Sugito N, Kuranaga Y, Inamoto T, Takahara K, et al. MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells. Oncotarget. 2017;8:33064-33077 pubmed publisher
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, et al. Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission. EMBO J. 2017;36:1330-1347 pubmed publisher
Xiao W, Gao Z, Duan Y, Yuan W, Ke Y. Notch signaling plays a crucial role in cancer stem-like cells maintaining stemness and mediating chemotaxis in renal cell carcinoma. J Exp Clin Cancer Res. 2017;36:41 pubmed publisher
Zhou B, Zeng S, Li N, Yu L, Yang G, Yang Y, et al. Angiogenic Factor With G Patch and FHA Domains 1 Is a Novel Regulator of Vascular Injury. Arterioscler Thromb Vasc Biol. 2017;37:675-684 pubmed publisher
Liu Y, Lu R, Gu J, Chen Y, Zhang X, Zhang L, et al. Aldehyde dehydrogenase 1A1 up-regulates stem cell markers in benzo[a]pyrene-induced malignant transformation of BEAS-2B cells. Environ Toxicol Pharmacol. 2016;45:241-50 pubmed publisher
Stavri S, Simionescu M, Kardassis D, Gafencu A. Krüppel-like factor 4 synergizes with CREB to increase the activity of apolipoprotein E gene promoter in macrophages. Biochem Biophys Res Commun. 2015;468:66-72 pubmed publisher
Li W, Liu M, Su Y, Zhou X, Liu Y, Zhang X. The Janus-faced roles of Krüppel-like factor 4 in oral squamous cell carcinoma cells. Oncotarget. 2015;6:44480-94 pubmed publisher
Kissing S, Hermsen C, Repnik U, Nesset C, von Bargen K, Griffiths G, et al. Vacuolar ATPase in phagosome-lysosome fusion. J Biol Chem. 2015;290:14166-80 pubmed publisher
Zheng Y, Zou F, Wang J, Yin G, Le V, Fei Z, et al. Photodynamic therapy-mediated cancer vaccination enhances stem-like phenotype and immune escape, which can be blocked by thrombospondin-1 signaling through CD47 receptor protein. J Biol Chem. 2015;290:8975-86 pubmed publisher
Shan T, Zhou C, Yang R, Yan F, Zhang P, Fu Y, et al. Lithium chloride promotes the odontoblast differentiation of hair follicle neural crest cells by activating Wnt/?-catenin signaling. Cell Biol Int. 2015;39:35-43 pubmed publisher
product information
CatalogNo :
11880-1-AP
AntigenName :
KLF4
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
Kruppel-like factor 4 (gut)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, chIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
EZF, GKLF, KLF4, Krueppel like factor 4, Kruppel like factor 4 (gut)
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC030811
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Metabolism;Neurology;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:500 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.