Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; human; loading ...; fig s2a
| Kühnl A, Musiol A, Heitzig N, Johnson D, Ehrhardt C, Grewal T, et al. Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus. MBio. 2018;9: pubmed publisher
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- flow cytometry; human; loading ...; fig 1b
- immunocytochemistry; human; loading ...
| Monel B, Compton A, Bruel T, Amraoui S, Burlaud Gaillard J, Roy N, et al. Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells. EMBO J. 2017;36:1653-1668 pubmed publisher
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| Sun Q, Lei N, Lu J, Gao R, Li Z, Liu L, et al. Interferon-induced Transmembrane Protein 3 Prevents Acute Influenza Pathogenesis in Mice. Biomed Environ Sci. 2020;33:295-305 pubmed publisher
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| Gobillot T, Humes D, Sharma A, Kikawa C, Overbaugh J. The Robust Restriction of Zika Virus by Type-I Interferon in A549 Cells Varies by Viral Lineage and Is Not Determined by IFITM3. Viruses. 2020;12: pubmed publisher
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| Wu X, Spence J, Das T, Yuan X, Chen C, Zhang Y, et al. Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase. Cell Chem Biol. 2020;27:571-585.e6 pubmed publisher
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| Lubow J, Virgilio M, Merlino M, Collins D, Mashiba M, Peterson B, et al. Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages. elife. 2020;9: pubmed publisher
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| Ali A, Syed S, Jamaluddin M, Colino Sanguino Y, Gallego Ortega D, Tanwar P. Cell Lineage Tracing Identifies Hormone-Regulated and Wnt-Responsive Vaginal Epithelial Stem Cells. Cell Rep. 2020;30:1463-1477.e7 pubmed publisher
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| Zani A, Zhang L, McMichael T, Kenney A, Chemudupati M, Kwiek J, et al. Interferon-Induced Transmembrane Proteins Inhibit Cell Fusion Mediated by Trophoblast Syncytins. J Biol Chem. 2019;: pubmed publisher
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| Hegyesi H, Sándor N, Safrany G, Lovas V, Kovacs A, Takács A, et al. Radio-detoxified LPS alters bone marrow-derived extracellular vesicles and endothelial progenitor cells. Stem Cell Res Ther. 2019;10:313 pubmed publisher
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| Wang Q, Su L. Vpr Enhances HIV-1 Env Processing and Virion Infectivity in Macrophages by Modulating TET2-Dependent IFITM3 Expression. MBio. 2019;10: pubmed publisher
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| Sharma A, McLaughlin R, Basom R, Kikawa C, OhAinle M, Yount J, et al. Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner. PLoS Pathog. 2019;15:e1007925 pubmed publisher
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| Kummer S, Avinoam O, Kräusslich H. IFITM3 Clusters on Virus Containing Endosomes and Lysosomes Early in the Influenza A Infection of Human Airway Epithelial Cells. Viruses. 2019;11: pubmed publisher
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| Du S, Jiang Y, Xu W, Bai J, Tian M, Wang M, et al. Construction, expression and antiviral activity analysis of recombinant adenovirus expressing human IFITM3 in vitro. Int J Biol Macromol. 2019;131:925-932 pubmed publisher
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| Spence J, He R, Hoffmann H, Das T, Thinon E, Rice C, et al. IFITM3 directly engages and shuttles incoming virus particles to lysosomes. Nat Chem Biol. 2019;15:259-268 pubmed publisher
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| Appourchaux R, Delpeuch M, Zhong L, Burlaud Gaillard J, Tartour K, Savidis G, et al. Functional Mapping of Regions Involved in the Negative Imprinting of Virion Particle Infectivity and in Target Cell Protection by Interferon-Induced Transmembrane Protein 3 against HIV-1. J Virol. 2019;93: pubmed publisher
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| Tammineni E, Carrillo E, Soto Acosta R, Angel Ambrocio A, Garcia M, Bautista Carbajal P, et al. The β4 subunit of Cav1.2 channels is required for an optimal interferon response in cardiac muscle cells. Sci Signal. 2018;11: pubmed publisher
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| Petrillo C, Thorne L, Unali G, Schiroli G, Giordano A, Piras F, et al. Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells. Cell Stem Cell. 2018;23:820-832.e9 pubmed publisher
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| Yu J, Liu S. The Inhibition of HIV-1 Entry Imposed by Interferon Inducible Transmembrane Proteins Is Independent of Co-Receptor Usage. Viruses. 2018;10: pubmed publisher
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| Xu B, Pan Q, Liang C. Role of MxB in Alpha Interferon-Mediated Inhibition of HIV-1 Infection. J Virol. 2018;92: pubmed publisher
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| McMichael T, Zhang Y, Kenney A, Zhang L, Zani A, Lu M, et al. IFITM3 Restricts Human Metapneumovirus Infection. J Infect Dis. 2018;218:1582-1591 pubmed publisher
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| Thinon E, Fernandez J, Molina H, Hang H. Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites. J Proteome Res. 2018;17:1907-1922 pubmed publisher
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| Roesch F, OhAinle M, Emerman M. A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery. Retrovirology. 2018;15:26 pubmed publisher
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| Li C, Du S, Tian M, Wang Y, Bai J, Tan P, et al. The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection. Front Immunol. 2018;9:228 pubmed publisher
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| Tsai C, Chi H, Chi L, Yang H, Tsai M, Lee K, et al. Argininosuccinate synthetase 1 contributes to gastric cancer invasion and progression by modulating autophagy. FASEB J. 2018;32:2601-2614 pubmed publisher
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| Shan J, Zhao B, Shan Z, Nie J, Deng R, Xiong R, et al. Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation. PLoS Pathog. 2017;13:e1006773 pubmed publisher
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| McMichael T, Zhang L, Chemudupati M, Hach J, Kenney A, Hang H, et al. The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity. J Biol Chem. 2017;292:21517-21526 pubmed publisher
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| Chesarino N, Compton A, McMichael T, Kenney A, Zhang L, Soewarna V, et al. IFITM3 requires an amphipathic helix for antiviral activity. EMBO Rep. 2017;18:1740-1751 pubmed publisher
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| Sareila O, Hagert C, Kelkka T, Linja M, Xu B, Kihlberg J, et al. Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms. Antioxid Redox Signal. 2017;27:1473-1490 pubmed publisher
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| Wrensch F, Hoffmann M, Gärtner S, Nehlmeier I, Winkler M, Pohlmann S. Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins. J Virol. 2017;91: pubmed publisher
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| Poddar S, Hyde J, Gorman M, Farzan M, Diamond M. The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses. J Virol. 2016;90:8780-94 pubmed publisher
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| Gorman M, Poddar S, Farzan M, Diamond M. The Interferon-Stimulated Gene Ifitm3 Restricts West Nile Virus Infection and Pathogenesis. J Virol. 2016;90:8212-25 pubmed publisher
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| Wilkins J, Zheng Y, Yu J, Liang C, Liu S. Nonhuman Primate IFITM Proteins Are Potent Inhibitors of HIV and SIV. PLoS ONE. 2016;11:e0156739 pubmed publisher
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| Muñoz Moreno R, Cuesta Geijo M, Martínez Romero C, Barrado Gil L, Galindo I, Garcia Sastre A, et al. Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection. PLoS ONE. 2016;11:e0154366 pubmed publisher
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| Zeng X, Wang S, Chi X, Chen S, Huang S, Lin Q, et al. Infection of goats with goatpox virus triggers host antiviral defense through activation of innate immune signaling. Res Vet Sci. 2016;104:40-9 pubmed publisher
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| Yu J, Li M, Wilkins J, Ding S, Swartz T, Esposito A, et al. IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein. Cell Rep. 2015;13:145-156 pubmed publisher
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| Koyama N, Hakura A, Toritsuka N, Sonoda J, Seki Y, Tohyama O, et al. Wif1 and Ifitm3 gene expression preferentially altered in the colon mucosa of benzo[a]pyrene pre-treated mice following exposure to dextran sulfate sodium. Chem Biol Interact. 2015;240:164-70 pubmed publisher
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| Chesarino N, McMichael T, Yount J. E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3. PLoS Pathog. 2015;11:e1005095 pubmed publisher
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| Chen Z, Luo G, Wang Q, Wang S, Chi X, Huang Y, et al. Muscovy duck reovirus infection rapidly activates host innate immune signaling and induces an effective antiviral immune response involving critical interferons. Vet Microbiol. 2015;175:232-43 pubmed publisher
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| Qian J, Le Duff Y, Wang Y, Pan Q, Ding S, Zheng Y, et al. Primate lentiviruses are differentially inhibited by interferon-induced transmembrane proteins. Virology. 2015;474:10-8 pubmed publisher
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| Yu M, Qi W, Huang Z, Zhang K, Ye J, Liu R, et al. Expression profile and histological distribution of IFITM1 and IFITM3 during H9N2 avian influenza virus infection in BALB/c mice. Med Microbiol Immunol. 2015;204:505-14 pubmed publisher
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| Zhang W, Zhang L, Zan Y, Du N, Yang Y, Tien P. Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins. J Gen Virol. 2015;96:170-82 pubmed publisher
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| Zhu X, He Z, Yuan J, Wen W, Huang X, Hu Y, et al. IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection. Cell Microbiol. 2015;17:105-18 pubmed publisher
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| Jia R, Xu F, Qian J, Yao Y, Miao C, Zheng Y, et al. Identification of an endocytic signal essential for the antiviral action of IFITM3. Cell Microbiol. 2014;16:1080-93 pubmed publisher
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