This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
GRP78/BIP
catalog :
11587-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
citations: 179
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 3a
Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, et al. Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma. Biomed Pharmacother. 2019;118:109188 pubmed publisher
  • western blot; human; loading ...; fig 7c
Du T, Li H, Fan Y, Yuan L, Guo X, Zhu Q, et al. The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis. Nat Commun. 2019;10:2914 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3e
Andrew R, Fisher K, Heesom K, Kellett K, Hooper N. Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms. J Neurochem. 2019;149:399-412 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 5a
Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X. PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways. Exp Ther Med. 2017;13:1993-1999 pubmed publisher
  • western blot; rat; 1:500; fig 2a
Wu J, Hu G, Lu Y, Zheng J, Chen J, Wang X, et al. Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein ?-CCAAT-enhancer-binding protein ? activation. Int J Biochem Cell Biol. 2016;79:181-193 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig s1
Sharoar M, Shi Q, Ge Y, He W, Hu X, Perry G, et al. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016;21:1263-71 pubmed publisher
Lin Q, Zhou S, Huang Y, Huo Z, Chen C, Luo X, et al. ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy. Front Microbiol. 2020;11:1745 pubmed publisher
Li B, Yao J, Guo K, He F, Chen K, Lin Z, et al. Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators. Eur J Med Chem. 2020;204:112608 pubmed publisher
Lu F, Lu B, Zhang L, Wen J, Wang M, Zhang S, et al. Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration. J Cell Mol Med. 2020;: pubmed publisher
Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, et al. Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1. J Cell Mol Med. 2020;: pubmed publisher
Lei Q, Yi T, Li H, Yan Z, Lv Z, Li G, et al. Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78). Sci Rep. 2020;10:10604 pubmed publisher
Wang Y, Li C, Li J, Wang G, Li L. Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
Pang X, Qiao Q, Vonglorkham S, Feng Z, Pang L, Chen S, et al. Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy. Biomed Pharmacother. 2020;129:110375 pubmed publisher
Tang X, Yu Q, Wen X, Qi D, Peng J, He J, et al. Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue. Shock. 2020;54:110-118 pubmed publisher
Zhang M, Ma Z, Li R, Guo S, Qiu Y, Gao X. Proteomic Analysis Reveals Proteins and Pathways Associated with Lactation in Bovine Mammary Epithelial Cell-Derived Exosomes. J Proteome Res. 2020;19:3211-3219 pubmed publisher
Liu C, Zhang A. ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling. Environ Toxicol. 2020;35:1100-1113 pubmed publisher
Liao D, Chen Y, Guo Y, Wang C, Liu N, Gong Q, et al. Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway. J Inflamm Res. 2020;13:195-206 pubmed publisher
Huang P, Guo Y, Zhao Z, Ning W, Wang H, Gu C, et al. UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT. Aging (Albany NY). 2020;12:10275-10289 pubmed publisher
Yang B, Qin Q, Xu L, Lv X, Liu Z, Song E, et al. Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36. Chem Res Toxicol. 2020;33:1497-1507 pubmed publisher
Jin Z, Chen Y, Weng X, Huang A, Lin S, Li H. Cleavage of cyclic AMP-responsive element-binding protein H aggravates myocardial hypoxia reperfusion injury in a hepatocyte-myocardial cell co-culture system. J Int Med Res. 2020;48:300060520904835 pubmed publisher
Xiong Y, Jin E, Yin Q, Che C, He S. Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells. Biol Trace Elem Res. 2020;: pubmed publisher
Sun S, Ji Z, Fu J, Wang X, Zhang L. Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway. Environ Sci Pollut Res Int. 2020;27:26163-26171 pubmed publisher
Hicks D, Jones A, Corbett N, Fisher K, Pickering Brown S, Ashe M, et al. Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network. Neurochem Res. 2020;45:1711-1728 pubmed publisher
Li S, Hao M, Li B, Chen M, Chen J, Tang J, et al. CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade. Cell Death Dis. 2020;11:279 pubmed publisher
Xiong Y, Xin D, Hu Q, Wang L, Qiu J, Yuan H, et al. Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage. Neural Regen Res. 2020;15:1920-1930 pubmed publisher
Zhou Z, Hu B, Lyu Q, Xie T, Wang J, Cai Q. miR-384-5p promotes spinal cord injury recovery in rats through suppressing of autophagy and endoplasmic reticulum stress. Neurosci Lett. 2020;727:134937 pubmed publisher
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, et al. Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biol. 2020;32:101514 pubmed publisher
Sümegi A, Hendrik Z, Gáll T, Felszeghy E, Szakszon K, Antal Szalmas P, et al. A novel splice site indel alteration in the EIF2AK3 gene is responsible for the first cases of Wolcott-Rallison syndrome in Hungary. BMC Med Genet. 2020;21:61 pubmed publisher
Zhang X, Wang Y, Tong J, Ning X, Zhou F, Yang X, et al. Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells. FEBS Open Bio. 2020;10:827-834 pubmed publisher
Yan W, Long P, Wei D, Yan W, Zheng X, Chen G, et al. Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study. BMC Ophthalmol. 2020;20:55 pubmed publisher
Sun F, Liao Y, Qu X, Xiao X, Hou S, Chen Z, et al. Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity. Cell Rep. 2020;30:1835-1847.e9 pubmed publisher
Samanta S, Tamura S, Dubeau L, Mhawech Fauceglia P, Miyagi Y, Kato H, et al. Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma. Sci Rep. 2020;10:2160 pubmed publisher
Xiong Y, Yin Q, Jin E, Chen H, He S. Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells. Molecules. 2020;25: pubmed publisher
Zhao L, Zhao J, Gao R, Tian Y, Zhang Y, Tang W, et al. Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis. Biomed Pharmacother. 2020;123:109783 pubmed publisher
Liu J, Wei L, Wang Z, Song S, Lin Z, Zhu J, et al. Protective effect of Liraglutide on diabetic retinal neurodegeneration via inhibiting oxidative stress and endoplasmic reticulum stress. Neurochem Int. 2020;133:104624 pubmed publisher
Zhang W, Zhu T, Chen L, Luo W, Chao J. MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR. Am J Physiol Heart Circ Physiol. 2020;318:H59-H71 pubmed publisher
Huang Y, Xiao Z, Guan Z, Shen Y, Jiang Y, Xu X, et al. A light-triggered self-reinforced nanoagent for targeted chemo-photodynamic therapy of breast cancer bone metastases via ER stress and mitochondria mediated apoptotic pathways. J Control Release. 2019;319:119-134 pubmed publisher
Harvey R, Pöyry T, Stoneley M, Willis A. Signaling from mTOR to eIF2α mediates cell migration in response to the chemotherapeutic doxorubicin. Sci Signal. 2019;12: pubmed publisher
Yang S, Zhu J, Zhou X, Wang H, Li X, Zhao A. Induction of the unfolded protein response (UPR) during pseudorabies virus infection. Vet Microbiol. 2019;239:108485 pubmed publisher
Ning J, Lin Z, Zhao X, Zhao B, Miao J. Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells. Cell Death Dis. 2019;10:858 pubmed publisher
Lv C, Wu H, Wu L, Xu G, Yang Z, Shen Q. Sevoflurane modulates AQPs (1,5) expression and endoplasmic reticulum stress in mice lung with allergic airway inflammation. Biosci Rep. 2019;39: pubmed publisher
Okubo K, Isono M, Asano T, Sato A. Lopinavir-Ritonavir Combination Induces Endoplasmic Reticulum Stress and Kills Urological Cancer Cells. Anticancer Res. 2019;39:5891-5901 pubmed publisher
Ma Y, Di Z, Cao Q, Xu W, Bi S, Yu J, et al. Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway. Acta Pharmacol Sin. 2019;: pubmed publisher
Liu Y, Wang X, Zhen Z, Yu Y, Qiu Y, Xiang W. GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway. Cell Mol Biol Lett. 2019;24:57 pubmed publisher
Tang Q, Ren L, Liu J, Li W, Zheng X, Wang J, et al. Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis. Cell Prolif. 2019;:e12706 pubmed publisher
Pan T, Li L, Zhang J, Yang Z, Shi D, Yang Y, et al. Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling. J Cancer. 2019;10:4777-4792 pubmed publisher
Hu J, Wu Q, Wang Z, Hong J, Chen R, Li B, et al. Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress. Biomed Pharmacother. 2019;120:109475 pubmed publisher
Xin X, Zhang R, Yuan X, Liu L. Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line. Med Sci Monit. 2019;25:7100-7114 pubmed publisher
Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, et al. Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway. Oxid Med Cell Longev. 2019;2019:8781690 pubmed publisher
Chen J, Hung C, Keller J, Lin H, Wu Y. Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation. BMC Ophthalmol. 2019;19:168 pubmed publisher
Hou Y, Fu J, Sun S, Jin Y, Wang X, Zhang L. BDE-209 induces autophagy and apoptosis via IRE1α/Akt/mTOR signaling pathway in human umbilical vein endothelial cells. Environ Pollut. 2019;253:429-438 pubmed publisher
Chang L, Wang Z, Ma F, Tran B, Zhong R, Xiong Y, et al. ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway. Oxid Med Cell Longev. 2019;2019:6173685 pubmed publisher
Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, et al. Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo. Theranostics. 2019;9:4084-4100 pubmed publisher
Hicks D, Cross L, Williamson R, Rattray M. Endoplasmic Reticulum Stress Signalling Induces Casein Kinase 1-Dependent Formation of Cytosolic TDP-43 Inclusions in Motor Neuron-Like Cells. Neurochem Res. 2019;: pubmed publisher
Luo R, Song Y, Liao Z, Yin H, Zhan S, Wang K, et al. Impaired calcium homeostasis via advanced glycation end products promotes apoptosis through endoplasmic reticulum stress in human nucleus pulposus cells and exacerbates intervertebral disc degeneration in rats. FEBS J. 2019;286:4356-4373 pubmed publisher
Wu T, Jiang N, Ji Z, Shi G. The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury. Life Sci. 2019;:116569 pubmed publisher
Liu L, Guo Y, Zheng J, Lu Y, Shen Y, Huang C, et al. Paneth cell ablation increases the small intestinal injury during acute necrotizing pancreatitis in rats. Mol Med Rep. 2019;20:473-484 pubmed publisher
Ye J, Qi L, Chen K, Li R, Song S, Zhou C, et al. Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo. Int J Oncol. 2019;55:331-339 pubmed publisher
Terajima M, Taga Y, Cabral W, Liu Y, Nagasawa M, Sumida N, et al. Cyclophilin B control of lysine post-translational modifications of skin type I collagen. PLoS Genet. 2019;15:e1008196 pubmed publisher
Xie Y, Zhou X, Yuan H, Qiu J, Xin D, Chu X, et al. Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress. Neural Regen Res. 2019;14:1734-1742 pubmed publisher
Huang W, Liang Y, Ma X. Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells. Cancer Cell Int. 2019;19:151 pubmed publisher
Xu W, Wu Y, Hu Z, Sun L, Dou G, Zhang Z, et al. Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity. Mol Ther Nucleic Acids. 2019;16:778-790 pubmed publisher
Tang S, Wang J, Liu J, Huang Y, Zhou Y, Yang S, et al. Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway. Ren Fail. 2019;41:455-466 pubmed publisher
Xu C, Zhou L, Wu K, Li Y, Xu J, Jiang D, et al. Abnormal Glucose Metabolism and Insulin Resistance Are Induced via the IRE1α/XBP-1 Pathway in Subclinical Hypothyroidism. Front Endocrinol (Lausanne). 2019;10:303 pubmed publisher
Sun J, Liu Y, Yu J, Wu J, Gao W, Ran L, et al. Effects of APS Activates Hepatic Insulin Signaling in HFD-induced IR Mice. J Mol Endocrinol. 2019;: pubmed publisher
Liu K, Liu Y, Xu Y, Nandakumar K, Shen X, Lin J, et al. Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and Aβ formation. J Cell Biochem. 2019;: pubmed publisher
Wu Y, Su T, Dai G, Su J, Liu C. Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway. Mar Drugs. 2019;17: pubmed publisher
Li H, Zhao W, Wang L, Luo Q, Yin N, Lu X, et al. Human placenta-derived mesenchymal stem cells inhibit apoptosis of granulosa cells induced by IRE1α pathway in autoimmune POF mice. Cell Biol Int. 2019;: pubmed publisher
Gao Z, Peng M, Chen L, Yang X, Li H, Shi R, et al. Prion Protein Protects Cancer Cells against Endoplasmic Reticulum Stress Induced Apoptosis. Virol Sin. 2019;34:222-234 pubmed publisher
Zhao Y, Yan J, Li A, Zhang Z, Li Z, Guo K, et al. Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats. Toxicol Lett. 2019;310:31-38 pubmed publisher
Wu S, Zhu X, Guo B, Zheng T, Ren J, Zeng W, et al. Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells. J Ophthalmol. 2019;2019:9028483 pubmed publisher
Cao X, He Y, Li X, Xu Y, Liu X. The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs. Am J Transl Res. 2019;11:641-654 pubmed
Li C, Li L, Chen K, Wang Y, YANG F, Wang G. UFL1 Alleviates Lipopolysaccharide-Induced Cell Damage and Inflammation via Regulation of the TLR4/NF-κB Pathway in Bovine Mammary Epithelial Cells. Oxid Med Cell Longev. 2019;2019:6505373 pubmed publisher
Moss S, Taylor I, Ruggero D, Gestwicki J, Shokat K, Mukherjee S. A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis. Cell Host Microbe. 2019;25:454-462.e6 pubmed publisher
Xu K, Han B, Bai Y, Ma X, Ji Z, Xiong Y, et al. MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer. Cell Death Dis. 2019;10:152 pubmed publisher
Wei Q, Zhang J, Su L, Zhao X, Zhao B, Miao J, et al. Low-concentration HCP1 inhibits apoptosis in vascular endothelial cells. Biochem Biophys Res Commun. 2019;511:92-98 pubmed publisher
Xu S, Di Z, He Y, Wang R, Ma Y, Sun R, et al. Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress. J Neuroinflammation. 2019;16:35 pubmed publisher
Sun X, Zhao D, Lu F, Peng S, Yu M, Liu N, et al. Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys44 to prevent cardiac structural damage in diabetic cardiomyopathy. Br J Pharmacol. 2019;: pubmed publisher
Gao L, Chen H, Li C, Xiao Y, Yang D, Zhang M, et al. ER stress activation impairs the expression of circadian clock and clock-controlled genes in NIH3T3 cells via an ATF4-dependent mechanism. Cell Signal. 2019;57:89-101 pubmed publisher
Chen Z, Chen J, Wu L, Li B, Tian Y, Xian M, et al. Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats. Biomed Environ Sci. 2019;32:1-10 pubmed publisher
Wu W, Li W, Wei J, Wang C, Yao Y, Zhu W, et al. Chronic intermittent hypoxia accelerates liver fibrosis in rats with combined hypoxia and nonalcoholic steatohepatitis via angiogenesis rather than endoplasmic reticulum stress. Acta Biochim Biophys Sin (Shanghai). 2019;51:159-167 pubmed publisher
Zhang Y, Sun R, Geng S, Shan Y, Li X, Fang W. Porcine Circovirus Type 2 Induces ORF3-Independent Mitochondrial Apoptosis via PERK Activation and Elevation of Cytosolic Calcium. J Virol. 2019;93: pubmed publisher
Dong Z, Coates D, Liu Q, Sun H, Li C. Quantitative proteomic analysis of deer antler stem cells as a model of mammalian organ regeneration. J Proteomics. 2019;195:98-113 pubmed publisher
Wei Y, Meng M, Tian Z, Xie F, Yin Q, Dai C, et al. Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis. Pharmacol Res. 2019;141:114-122 pubmed publisher
Guo L, Ma L, Liu C, Lei Y, Tang N, Huang Y, et al. ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer. Oncol Rep. 2019;41:1603-1615 pubmed publisher
Ullah O, Li Z, Ali I, Xu L, Liu H, Jin H, et al. Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos. In Vitro Cell Dev Biol Anim. 2019;55:82-93 pubmed publisher
Nie J, Duan Q, He M, Li X, Wang B, Zhou C, et al. Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na+ and Ca2+ handling. J Cell Physiol. 2019;234:11587-11601 pubmed publisher
Li S, Jiang Z, Chai W, Xu Y, Wang Y. Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons. Neurochem Int. 2019;122:73-84 pubmed publisher
Jia Y, Li Z, Feng Y, Cui R, Dong Y, Zhang X, et al. Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress. Oxid Med Cell Longev. 2018;2018:4756846 pubmed publisher
Cao X, Dai Y, Liu M, Yuan X, Wang C, Huang Y, et al. High-fat diet induces aberrant hepatic lipid secretion in blunt snout bream by activating endoplasmic reticulum stress-associated IRE1/XBP1 pathway. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1864:213-223 pubmed publisher
Gáll T, Pethő D, Nagy A, Hendrik Z, Mehes G, Potor L, et al. Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells. Front Physiol. 2018;9:1595 pubmed publisher
Zhu J, Wang R, Xu T, Zhang S, Zhao Y, Li Z, et al. Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway. Front Pharmacol. 2018;9:1277 pubmed publisher
Zhao M, Zhang X, Gao L, Song Y, Xu C, Yu C, et al. Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?. Int J Endocrinol. 2018;2018:4215848 pubmed publisher
Peng X, Yang T, He L, Chen X, Jiang Y, Zhang H, et al. Impact of GADD34 on Apoptosis of Tonsillar Mononuclear Cells from IgA Nephropathy Patients by Regulating Eif2α Phosphorylation. Cell Physiol Biochem. 2018;50:2203-2215 pubmed publisher
Liu Z, Dong W, Yang B, Peng L, Xia X, Pu L, et al. Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis. Chem Res Toxicol. 2018;31:1230-1239 pubmed publisher
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, et al. Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism. Int Immunopharmacol. 2018;65:256-267 pubmed publisher
Jin G, Zhang Y, Cong W, Wu X, Wang X, Wu S, et al. Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking. PLoS Biol. 2018;16:e2006483 pubmed publisher
Liao D, Xiang D, Dang R, Xu P, Wang J, Han W, et al. Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes. Oxid Med Cell Longev. 2018;2018:9125601 pubmed publisher
Xu Y, Sun D, Song C, Wang R, Dong X. MnTMPyP inhibits paraquat-induced pulmonary epithelial-like cell injury by inhibiting oxidative stress. J Toxicol Sci. 2018;43:545-555 pubmed publisher
Chen Y, Zhang B, Cao S, Huang W, Liu N, Yang W. GanDouLing combined with Penicillamine improves cerebrovascular injury via PERK/eIF2α/CHOP endoplasmic reticulum stress pathway in the mouse model of Wilson's disease. Biosci Rep. 2018;38: pubmed publisher
Lee K, Haddad A, Osme A, Kim C, Borzou A, Ilchenko S, et al. Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits. Mol Cell Proteomics. 2018;17:2371-2386 pubmed publisher
Men L, Yu S, Yao J, Li Y, Ren D, Du J. Selenoprotein S protects against adipocyte death through mediation of the IRE1α-sXBP1 pathway. Biochem Biophys Res Commun. 2018;503:2866-2871 pubmed publisher
Duan Y, Jin Y, Guo M, Duan L, Wang J. Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture. J Cancer. 2018;9:2723-2733 pubmed publisher
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, et al. Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity. Sci Total Environ. 2018;645:363-371 pubmed publisher
Geng W, Qin F, Ren J, Xiao S, Wang A. Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice. Exp Cell Res. 2018;369:243-250 pubmed publisher
Wang X, Han X, Li M, Han Y, Zhang Y, Zhao S, et al. Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress. Microvasc Res. 2018;119:98-104 pubmed publisher
Li Z, Meng Z, Lu J, Chen F, Wong W, Tse G, et al. TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2018;120:1-11 pubmed publisher
Montibeller L, de Belleroche J. Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes. Cell Stress Chaperones. 2018;23:897-912 pubmed publisher
Li Y, Xie Y, Hao J, Liu J, Ning Y, Tang Q, et al. ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration. Exp Cell Res. 2018;368:167-173 pubmed publisher
Xu J, Wang J, Cheng Y, Li X, He M, Zhu J, et al. Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats. Biomed Res Int. 2018;2018:1864107 pubmed publisher
Wang Z, Cui R, Wang K. Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78. Exp Ther Med. 2018;15:2818-2823 pubmed publisher
Lee Y, Lin K, Wu B, Chuang S, Wu W, Lee Y, et al. Epigallocatechin-3-gallate alleviates bladder overactivity in a rat model with metabolic syndrome and ovarian hormone deficiency through mitochondria apoptosis pathways. Sci Rep. 2018;8:5358 pubmed publisher
Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T. Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells. Oxid Med Cell Longev. 2018;2018:3853409 pubmed publisher
Deng Q, Liang L, Liu Q, Duan W, Jiang Y, Zhang L. Autophagy is a major mechanism for the dual effects of curcumin on renal cell carcinoma cells. Eur J Pharmacol. 2018;826:24-30 pubmed publisher
Aumailley L, Roux Dalvai F, Kelly I, Droit A, Lebel M. Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein. PLoS ONE. 2018;13:e0193170 pubmed publisher
Cui X, Zhou Z, Zhu K, Feng R, Han J, Li M, et al. A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function. DNA Cell Biol. 2018;37:449-456 pubmed publisher
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product information
CatalogNo :
11587-1-AP
AntigenName :
GRP78/BIP
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Immunogen :
Recombinant Protein
Species :
bovine, chicken, cow, hamster, human, mouse, porcine, rat, sika deer, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, CoIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
BIP, GRP 78, GRP78, Heat shock 70 kDa protein 5, HSP A5, HSPA5, MIF2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC020235
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Immunology;Membrane Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:200 ; IP 1:1000 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.