| Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:1000; loading ...; fig 1d
| Yasuda K, Clatterbuck Soper S, Jackrel M, Shorter J, Mili S. FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination. J Cell Biol. 2017;216:1015-1034 pubmed publisher |
| Zhu Y, Liu Y, Yang F, Chen W, Jiang J, He P, et al. All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice. Mol Neurobiol. 2020;57:3603-3615 pubmed publisher |
| Pourhaghighi R, Ash P, Phanse S, Goebels F, Hu L, Chen S, et al. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst. 2020;10:333-350.e14 pubmed publisher |
| Han K, Wang F, Cao C, Ling H, Chen J, Chen R, et al. CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17. Mol Cancer. 2020;19:60 pubmed publisher |
| Ikenaka K, Ishigaki S, Iguchi Y, Kawai K, Fujioka Y, Yokoi S, et al. Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis. J Neuropathol Exp Neurol. 2020;79:370-377 pubmed publisher |
| Kuta R, Larochelle N, Fernandez M, Pal A, Minotti S, Tibshirani M, et al. Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models. Cell Stress Chaperones. 2020;25:173-191 pubmed publisher |
| Shelkovnikova T, An H, Skelt L, Tregoning J, Humphreys I, Buchman V. Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis. Cell Rep. 2019;29:4496-4508.e4 pubmed publisher |
| Casci I, Krishnamurthy K, Kour S, Tripathy V, Ramesh N, Anderson E, et al. Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization. Nat Commun. 2019;10:5583 pubmed publisher |
| Picchiarelli G, Demestre M, Zuko A, Been M, Higelin J, Dieterlé S, et al. FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis. Nat Neurosci. 2019;22:1793-1805 pubmed publisher |
| Rossaert E, Pollari E, Jaspers T, Van Helleputte L, Jarpe M, Van Damme P, et al. Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model. Acta Neuropathol Commun. 2019;7:107 pubmed publisher |
| Shi X, Wang X. LINC00473 mediates cyclin D1 expression through a balance between activation and repression signals in breast cancer cells. FEBS Lett. 2019;593:751-759 pubmed publisher |
| Baron D, Matheny T, Lin Y, Leszyk J, Kenna K, Gall K, et al. Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS. Hum Mol Genet. 2019;: pubmed publisher |
| He Z, Ruan X, Liu X, Zheng J, Liu Y, Liu L, et al. FUS/circ_002136/miR-138-5p/SOX13 feedback loop regulates angiogenesis in Glioma. J Exp Clin Cancer Res. 2019;38:65 pubmed publisher |
| Withers J, Li E, Vallery T, Yario T, Steitz J. Two herpesviral noncoding PAN RNAs are functionally homologous but do not associate with common chromatin loci. PLoS Pathog. 2018;14:e1007389 pubmed publisher |
| López Erauskin J, Tadokoro T, Baughn M, Myers B, McAlonis Downes M, Chillon Marinas C, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2018;100:816-830.e7 pubmed publisher |
| Wang H, Guo W, Mitra J, Hegde P, Vandoorne T, Eckelmann B, et al. Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis. Nat Commun. 2018;9:3683 pubmed publisher |
| Xiong D, Wu Y, Jin C, Li J, Gu J, Liao Y, et al. Elevated FUS/TLS expression is negatively associated with E-cadherin expression and prognosis of patients with non-small cell lung cancer. Oncol Lett. 2018;16:1791-1800 pubmed publisher |
| Shelkovnikova T, Kukharsky M, An H, Dimasi P, Alexeeva S, Shabir O, et al. Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis. Mol Neurodegener. 2018;13:30 pubmed publisher |
| Guo L, Kim H, Wang H, Monaghan J, Freyermuth F, Sung J, et al. Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains. Cell. 2018;173:677-692.e20 pubmed publisher |
| Cykowski M, Powell S, Appel J, Arumanayagam A, Rivera A, Appel S. Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis. Acta Neuropathol Commun. 2018;6:28 pubmed publisher |
| Mitsuhashi H, Ishimaru S, Homma S, Yu B, Honma Y, Beermann M, et al. Functional domains of the FSHD-associated DUX4 protein. Biol Open. 2018;7: pubmed publisher |
| Kahl A, Blanco I, Jackman K, Baskar J, Milaganur Mohan H, Rodney Sandy R, et al. Cerebral ischemia induces the aggregation of proteins linked to neurodegenerative diseases. Sci Rep. 2018;8:2701 pubmed publisher |
| Irwin D, McMillan C, Xie S, Rascovsky K, Van Deerlin V, Coslett H, et al. Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia. Brain. 2018;141:288-301 pubmed publisher |
| Kovacs G, Kwong L, Grossman M, Irwin D, Lee E, Robinson J, et al. Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases. Brain Pathol. 2018;28:274-283 pubmed publisher |
| Lyons S, Gudanis D, Coyne S, Gdaniec Z, Ivanov P. Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs. Nat Commun. 2017;8:1127 pubmed publisher |
| Lo Bello M, Di Fini F, Notaro A, Spataro R, Conforti F, La Bella V. ALS-Related Mutant FUS Protein Is Mislocalized to Cytoplasm and Is Recruited into Stress Granules of Fibroblasts from Asymptomatic FUS P525L Mutation Carriers. Neurodegener Dis. 2017;17:292-303 pubmed publisher |
| Tibshirani M, Zhao B, Gentil B, Minotti S, Marques C, Keith J, et al. Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis. Hum Mol Genet. 2017;26:4142-4152 pubmed publisher |
| Hawley Z, Campos Melo D, Strong M. Novel miR-b2122 regulates several ALS-related RNA-binding proteins. Mol Brain. 2017;10:46 pubmed publisher |
| Shelkovnikova T, Dimasi P, Kukharsky M, An H, Quintiero A, Schirmer C, et al. Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly. Cell Death Dis. 2017;8:e2788 pubmed publisher |
| Scekic Zahirovic J, Oussini H, Mersmann S, Drenner K, Wagner M, Sun Y, et al. Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis. Acta Neuropathol. 2017;133:887-906 pubmed publisher |
| Kar A, Vargas J, Chen C, Kowalak J, Gioio A, Kaplan B. Molecular determinants of cytochrome C oxidase IV mRNA axonal trafficking. Mol Cell Neurosci. 2017;80:32-43 pubmed publisher |
| Homma S, Beermann M, Yu B, BOYCE F, Miller J. Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4. Skelet Muscle. 2016;6:42 pubmed |
| Chen Y, Deng J, Wang P, Yang M, Chen X, Zhu L, et al. PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration. Hum Mol Genet. 2016;25:5059-5068 pubmed publisher |
| Kapeli K, Pratt G, Vu A, Hutt K, Martinez F, Sundararaman B, et al. Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nat Commun. 2016;7:12143 pubmed publisher |
| Van den Bossche T, Sleegers K, Cuyvers E, Engelborghs S, Sieben A, De Roeck A, et al. Phenotypic characteristics of Alzheimer patients carrying an ABCA7 mutation. Neurology. 2016;86:2126-33 pubmed publisher |
| Schoen M, Reichel J, Demestre M, Putz S, Deshpande D, Proepper C, et al. Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons. Front Cell Neurosci. 2015;9:496 pubmed publisher |
| Lim S, Choi W, Oh K, Xue Y, Choi J, Kim S, et al. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis. Mol Neurodegener. 2016;11:8 pubmed publisher |
| He J, Huang L, Qiu H, Li J, Luo L, Li Y, et al. A new design of a lentiviral shRNA vector with inducible co-expression of ARGONAUTE 2 for enhancing gene silencing efficiency. Cell Biosci. 2015;5:67 pubmed publisher |
| Muresan V, Ladescu Muresan Z. Shared Molecular Mechanisms in Alzheimer's Disease and Amyotrophic Lateral Sclerosis: Neurofilament-Dependent Transport of sAPP, FUS, TDP-43 and SOD1, with Endoplasmic Reticulum-Like Tubules. Neurodegener Dis. 2016;16:55-61 pubmed publisher |
| King A, Troakes C, Smith B, Nolan M, Curran O, Vance C, et al. ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation. Acta Neuropathol Commun. 2015;3:62 pubmed publisher |
| Robinson H, Deykin A, Bronovitsky E, Ovchinnikov R, Ustyugov A, Shelkovnikova T, et al. Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif. Amyotroph Lateral Scler Frontotemporal Degener. 2015;16:402-9 pubmed publisher |
| Bakkar N, Kousari A, Kovalik T, Li Y, Bowser R. RBM45 Modulates the Antioxidant Response in Amyotrophic Lateral Sclerosis through Interactions with KEAP1. Mol Cell Biol. 2015;35:2385-99 pubmed publisher |
| Tibshirani M, Tradewell M, Mattina K, Minotti S, Yang W, Zhou H, et al. Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1. Hum Mol Genet. 2015;24:773-86 pubmed publisher |
