This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
STIM1
catalog :
11565-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 20
Reference
Angenendt A, Steiner R, Knörck A, Schwär G, Konrad M, Krause E, et al. Orai, STIM, and PMCA contribute to reduced calcium signal generation in CD8+ T cells of elderly mice. Aging (Albany NY). 2020;12:3266-3286 pubmed publisher
Stein B, Calzolari D, Hellberg K, Hu Y, He L, Hung C, et al. Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. Cell Rep. 2019;29:3331-3348.e7 pubmed publisher
Kulkarni R, Elmi A, Alcantara Adap E, Hubrack S, Nader N, Yu F, et al. miRNA-dependent regulation of STIM1 expression in breast cancer. Sci Rep. 2019;9:13076 pubmed publisher
Togao M, Nakayama S, Ikenaka Y, Mizukawa H, Makino Y, Kubota A, et al. Bioimaging of Pb and STIM1 in mice liver, kidney and brain using Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) and immunohistochemistry. Chemosphere. 2019;238:124581 pubmed publisher
Li S, Yao M, Niu C, Liu D, Tang Z, Gu C, et al. Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel. Biochem Biophys Res Commun. 2019;516:1066-1072 pubmed publisher
Yu F, Hubrack S, Chakraborty S, Sun L, Alcantara Adap E, Kulkarni R, et al. Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis. Proc Natl Acad Sci U S A. 2019;116:10392-10401 pubmed publisher
Kang F, Zhou M, Huang X, Fan J, Wei L, Boulanger J, et al. E-syt1 Re-arranges STIM1 Clusters to Stabilize Ring-shaped ER-PM Contact Sites and Accelerate Ca2+ Store Replenishment. Sci Rep. 2019;9:3975 pubmed publisher
Wu L, Zhang D, Zhou L, Pei Y, Zhuang Y, Cui W, et al. FUN14 domain-containing 1 promotes breast cancer proliferation and migration by activating calcium-NFATC1-BMI1 axis. EBioMedicine. 2019;41:384-394 pubmed publisher
Yang Z, Pan L, Liu S, Li F, Lv W, Shu Y, et al. Inhibition of stromal-interacting molecule 1-mediated store-operated Ca2+ entry as a novel strategy for the treatment of acquired imatinib-resistant gastrointestinal stromal tumors. Cancer Sci. 2018;109:2792-2800 pubmed publisher
Sharma A, Ramena G, Yin Y, PREMKUMAR L, Elble R. CLCA2 is a positive regulator of store-operated calcium entry and TMEM16A. PLoS ONE. 2018;13:e0196512 pubmed publisher
Kircher S, Merino Wong M, Niemeyer B, Alansary D. Profiling calcium signals of in vitro polarized human effector CD4+ T cells. Biochim Biophys Acta Mol Cell Res. 2018;1865:932-943 pubmed publisher
Zhang S, Miao Y, Zheng X, Gong Y, Zhang J, Zou F, et al. STIM1 and STIM2 differently regulate endogenous Ca2+ entry and promote TGF-?-induced EMT in breast cancer cells. Biochem Biophys Res Commun. 2017;488:74-80 pubmed publisher
Soni D, Regmi S, Wang D, Debroy A, Zhao Y, Vogel S, et al. Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca2+ entry regulates disassembly of adherens junctions. Am J Physiol Lung Cell Mol Physiol. 2017;312:L1003-L1017 pubmed publisher
Huang W, Ren C, Huang G, Liu J, Liu W, Wang L, et al. Inhibition of store-operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate. Oncol Lett. 2017;13:921-929 pubmed publisher
Shi J, Miralles F, Kinet J, Birnbaumer L, Large W, Albert A. Evidence that Orai1 does not contribute to store-operated TRPC1 channels in vascular smooth muscle cells. Channels (Austin). 2017;11:329-339 pubmed publisher
Gruszczynska Biegala J, Sladowska M, Kuznicki J. AMPA Receptors Are Involved in Store-Operated Calcium Entry and Interact with STIM Proteins in Rat Primary Cortical Neurons. Front Cell Neurosci. 2016;10:251 pubmed
Shi J, Miralles F, Birnbaumer L, Large W, Albert A. Store-operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells. J Physiol. 2017;595:1039-1058 pubmed publisher
Zhang H, Sun A, Kim J, Graham V, FINCH E, Nepliouev I, et al. STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node. Proc Natl Acad Sci U S A. 2015;112:E5618-27 pubmed publisher
MacGlashan D. Expression profiling of human basophils: modulation by cytokines and secretagogues. PLoS ONE. 2015;10:e0126435 pubmed publisher
Wang Y, Chaudhari S, Ren Y, Ma R. Impairment of hepatic nuclear factor-4α binding to the Stim1 promoter contributes to high glucose-induced upregulation of STIM1 expression in glomerular mesangial cells. Am J Physiol Renal Physiol. 2015;308:F1135-45 pubmed publisher
product information
CatalogNo :
11565-1-AP
AntigenName :
STIM1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
stromal interaction molecule 1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
D11S4896E, GOK, STIM1, stromal interaction molecule 1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC021300
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Neurology;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:25 ; IHC 1:50 ; IP 1:1000 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.