This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CENPJ
catalog :
11517-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 5c
Kim J, Ki S, Joung J, Scott E, Heynen Genel S, Aza Blanc P, et al. Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation. Biochim Biophys Acta. 2016;1863:1307-18 pubmed publisher
Shohayeb B, Ho U, Yeap Y, Parton R, Millard S, Xu Z, et al. The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development. Hum Mol Genet. 2020;29:248-263 pubmed publisher
Holdgaard S, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen J, et al. Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. Nat Commun. 2019;10:4176 pubmed publisher
Ganapathi Sankaran D, Stemm Wolf A, Pearson C. CEP135 isoform dysregulation promotes centrosome amplification in breast cancer cells. Mol Biol Cell. 2019;30:1230-1244 pubmed publisher
Ding W, Wu Q, Sun L, Pan N, Wang X. Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex. J Neurosci. 2019;39:1994-2010 pubmed publisher
Inoko A, Yano T, Miyamoto T, Matsuura S, Kiyono T, Goshima N, et al. Albatross/FBF1 contributes to both centriole duplication and centrosome separation. Genes Cells. 2018;23:1023-1042 pubmed publisher
Sydor A, Coyaud E, Rovelli C, Laurent E, Liu H, Raught B, et al. PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN. elife. 2018;7: pubmed publisher
Ogungbenro Y, Tena T, Gaboriau D, Lalor P, Dockery P, Philipp M, et al. Centrobin controls primary ciliogenesis in vertebrates. J Cell Biol. 2018;217:1205-1215 pubmed publisher
Gupta A, Tsuchiya Y, Ohta M, Shiratsuchi G, Kitagawa D. NEK7 is required for G1 progression and procentriole formation. Mol Biol Cell. 2017;28:2123-2134 pubmed publisher
Jayaraman D, Kodani A, Gonzalez D, Mancias J, Mochida G, Vagnoni C, et al. Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate. Neuron. 2016;92:813-828 pubmed publisher
Watanabe Y, Honda S, Konishi A, Arakawa S, Murohashi M, Yamaguchi H, et al. Autophagy controls centrosome number by degrading Cep63. Nat Commun. 2016;7:13508 pubmed publisher
Fu W, Wang L, Kim S, Li J, Dynlacht B. Role for the IFT-A Complex in Selective Transport to the Primary Cilium. Cell Rep. 2016;17:1505-1517 pubmed publisher
Tsuchiya Y, Yoshiba S, Gupta A, Watanabe K, Kitagawa D. Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole. Nat Commun. 2016;7:12567 pubmed publisher
Meitinger F, Anzola J, Kaulich M, Richardson A, Stender J, Benner C, et al. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016;214:155-66 pubmed publisher
Kim M, O Rourke B, Soni R, Jallepalli P, Hendrickson R, Tsou M. Promotion and Suppression of Centriole Duplication Are Catalytically Coupled through PLK4 to Ensure Centriole Homeostasis. Cell Rep. 2016;16:1195-1203 pubmed publisher
Wang W, Acehan D, Kao C, Jane W, Uryu K, Tsou M. De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly. elife. 2015;4: pubmed publisher
Dahl K, Sankaran D, Bayless B, Pinter M, Galati D, Heasley L, et al. A Short CEP135 Splice Isoform Controls Centriole Duplication. Curr Biol. 2015;25:2591-6 pubmed publisher
Van de Mark D, Kong D, Loncarek J, Stearns T. MDM1 is a microtubule-binding protein that negatively regulates centriole duplication. Mol Biol Cell. 2015;26:3788-802 pubmed publisher
Shukla A, Kong D, Sharma M, Magidson V, Loncarek J. Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation. Nat Commun. 2015;6:8077 pubmed publisher
Wong Y, Anzola J, Davis R, Yoon M, Motamedi A, Kroll A, et al. Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4. Science. 2015;348:1155-60 pubmed publisher
Garcez P, Díaz Alonso J, Crespo Enríquez I, Castro D, Bell D, Guillemot F. Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1. Nat Commun. 2015;6:6474 pubmed publisher
Gudi R, Haycraft C, Bell P, Li Z, Vasu C. Centrobin-mediated regulation of the centrosomal protein 4.1-associated protein (CPAP) level limits centriole length during elongation stage. J Biol Chem. 2015;290:6890-902 pubmed publisher
Shiratsuchi G, Takaoka K, Ashikawa T, Hamada H, Kitagawa D. RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity. EMBO J. 2015;34:97-114 pubmed publisher
product information
CatalogNo :
11517-1-AP
AntigenName :
CENPJ
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
centromere protein J
Immunogen :
Recombinant Protein
Species :
human, mouse, rat, zebra fish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
BM032, CENP J, CENPJ, centromere protein J, CPAP, LAG 3 associated protein, LAP, LIP1, LYST interacting protein 1, MCPH6
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC024209
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Organelle Marker;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; WB 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.