This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
YME1L1
catalog :
11510-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, western blot knockout validation
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 6g
Richter F, Dennerlein S, Nikolov M, Jans D, Naumenko N, Aich A, et al. ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. J Cell Biol. 2019;218:598-614 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2b
Tsai C, Wu Y, Pao P, Phillips C, Williams C, Miller C, et al. Proteolytic control of the mitochondrial calcium uniporter complex. Proc Natl Acad Sci U S A. 2017;114:4388-4393 pubmed publisher
Horibata Y, Mitsuhashi S, Shimizu H, Maejima S, Sakamoto H, Aoyama C, et al. The phosphatidylcholine transfer protein StarD7 is important for myogenic differentiation in mouse myoblast C2C12 cells and human primary skeletal myoblasts. Sci Rep. 2020;10:2845 pubmed publisher
Anderson C, Kahl A, Fruitman H, Qian L, Zhou P, Manfredi G, et al. Prohibitin levels regulate OMA1 activity and turnover in neurons. Cell Death Differ. 2019;: pubmed publisher
Crisol B, Veiga C, Braga R, Lenhare L, Baptista I, Gaspar R, et al. NAD+ precursor increases aerobic performance in mice. Eur J Nutr. 2019;: pubmed publisher
Zhao Y, Sun X, Hu D, Prosdocimo D, Hoppel C, Jain M, et al. ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects. Nat Commun. 2019;10:1371 pubmed publisher
Mohanraj K, Wasilewski M, Benincá C, Cysewski D, Poznanski J, Sakowska P, et al. Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7. EMBO Mol Med. 2019;11: pubmed publisher
Nakazawa H, Ikeda K, Shinozaki S, Yasuhara S, Yu Y, Martyn J, et al. Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle. FEBS Open Bio. 2019;9:348-363 pubmed publisher
Sekine S, Wang C, Sideris D, Bunker E, Zhang Z, Youle R. Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1. Mol Cell. 2019;73:1028-1043.e5 pubmed publisher
Sprenger H, Wani G, Hesseling A, König T, Patron M, MacVicar T, et al. Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 2019;11: pubmed publisher
Zurita Rendón O, Shoubridge E. LONP1 Is Required for Maturation of a Subset of Mitochondrial Proteins, and Its Loss Elicits an Integrated Stress Response. Mol Cell Biol. 2018;38: pubmed publisher
Consolato F, Maltecca F, Tulli S, Sambri I, Casari G. m-AAA and i-AAA complexes coordinate to regulate OMA1, the stress-activated supervisor of mitochondrial dynamics. J Cell Sci. 2018;131: pubmed publisher
Saita S, Tatsuta T, Lampe P, König T, Ohba Y, Langer T. PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. EMBO J. 2018;37: pubmed publisher
Wu L, Chang H, Ting P, Wang D. Laminar shear stress promotes mitochondrial homeostasis in endothelial cells. J Cell Physiol. 2018;233:5058-5069 pubmed publisher
Vukotic M, Nolte H, König T, Saita S, Ananjew M, Kruger M, et al. Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria. Mol Cell. 2017;67:471-483.e7 pubmed publisher
Saita S, Nolte H, Fiedler K, Kashkar H, Venne A, Zahedi R, et al. PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. Nat Cell Biol. 2017;19:318-328 pubmed publisher
Wai T, Saita S, Nolte H, Müller S, König T, Richter Dennerlein R, et al. The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L. EMBO Rep. 2016;17:1844-1856 pubmed
Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, et al. Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016;97:1-14 pubmed publisher
Richter U, Lahtinen T, Marttinen P, Suomi F, Battersby B. Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness. J Cell Biol. 2015;211:373-89 pubmed publisher
Baburamani A, Hurling C, Stolp H, Sobotka K, Gressens P, Hagberg H, et al. Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury. Int J Mol Sci. 2015;16:22509-26 pubmed publisher
Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, et al. Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization. Cell Death Differ. 2016;23:380-92 pubmed publisher
product information
CatalogNo :
11510-1-AP
AntigenName :
YME1L1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
YME1-like 1 (S. cerevisiae)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
FTSH, FTSH1, Meg 4, MEG4, PAMP, YME1 like 1 (S. cerevisiae), YME1 like protein 1, YME1L, YME1L1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC023507
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:200 ; IP 1:500 ; WB 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.