This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
MTAP
catalog :
11475-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; fig 3
  • western blot; human; fig 4
Bistulfi G, Affronti H, Foster B, Karasik E, Gillard B, Morrison C, et al. The essential role of methylthioadenosine phosphorylase in prostate cancer. Oncotarget. 2016;7:14380-93 pubmed publisher
Zhang T, Bauer C, Newman A, Uribe A, Athineos D, Blyth K, et al. Polyamine pathway activity promotes cysteine essentiality in cancer cells. Nat Metab. 2020;: pubmed publisher
Affronti H, Rowsam A, Pellerite A, Rosario S, Long M, Jacobi J, et al. Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy. Nat Commun. 2020;11:52 pubmed publisher
Guo J, Li X, Zhang W, Chen Y, Zhu S, Chen L, et al. HSP60-regulated Mitochondrial Proteostasis and Protein Translation Promote Tumor Growth of Ovarian Cancer. Sci Rep. 2019;9:12628 pubmed publisher
Abrahão Machado L, Antunes B, Filippi R, Volc S, Boldrini E, Menezes W, et al. Loss of MTAP expression is a negative prognostic marker in Ewing sarcoma family of tumors. Biomark Med. 2018;12:35-44 pubmed publisher
Tamiya H, Kim H, Klymenko O, Kim H, Feng Y, Zhang T, et al. SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth. J Clin Invest. 2018;128:517-530 pubmed publisher
Affronti H, Long M, Rosario S, Gillard B, Karasik E, Boerlin C, et al. Dietary folate levels alter the kinetics and molecular mechanism of prostate cancer recurrence in the CWR22 model. Oncotarget. 2017;8:103758-103774 pubmed publisher
Henrich F, Singer K, Poller K, Bernhardt L, Strobl C, Limm K, et al. Suppressive effects of tumor cell-derived 5'-deoxy-5'-methylthioadenosine on human T cells. Oncoimmunology. 2016;5:e1184802 pubmed publisher
He H, Lee Y, Shiue Y, Lee S, Chen T, Li C. Characterization and Prognostic Significance of Methylthioadenosine Phosphorylase Deficiency in Nasopharyngeal Carcinoma. Medicine (Baltimore). 2015;94:e2271 pubmed publisher
Becker A, Scapulatempo Neto C, Menezes W, Clara C, Machado H, Oliveira R, et al. Expression of Methylthioadenosine Phosphorylase (MTAP) in Pilocytic Astrocytomas. Pathobiology. 2015;82:84-9 pubmed publisher
product information
CatalogNo :
11475-1-AP
AntigenName :
MTAP
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
methylthioadenosine phosphorylase
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
c86fus, MSAP, MTA phosphorylase, MTAP, MTAPase
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC018625
Category :
Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:50 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.