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product summary
company name :
Proteintech Group
product type :
antibody
product name :
VCAM-1
catalog :
11444-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry
citations: 37
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:500; loading ...; fig 6f
Zhou Z, Zhou Q, Wu X, Xu S, Hu X, Tao X, et al. VCAM-1 secreted from cancer-associated fibroblasts enhances the growth and invasion of lung cancer cells through AKT and MAPK signaling. Cancer Lett. 2020;473:62-73 pubmed publisher
Wu B, Jiang M, Liu X, Huang C, Gu Z, Cao Y. Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo. Nanotoxicology. 2020;:1-22 pubmed publisher
Jiang Y, Jiang L, Wang Y, Ma D, Li X. Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence. Front Pharmacol. 2020;11:512 pubmed publisher
Xiao H, Sun X, Liu R, Chen Z, Lin Z, Yang Y, et al. Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy. Pharmacol Res. 2020;151:104559 pubmed publisher
Liu C, Feng R, Zou J, Xia F, Wan J. 20(S)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of Panax notoginseng in ApoE Deficient Mice. Molecules. 2019;24: pubmed publisher
Yang S, Chen Y, Duan Y, Ma C, Liu L, Li Q, et al. Therapeutic potential of NaoXinTong Capsule on the developed diabetic nephropathy in db/db mice. Biomed Pharmacother. 2019;118:109389 pubmed publisher
Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, et al. Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis. Pharmacol Res. 2019;148:104414 pubmed publisher
He M, Long P, Guo L, Zhang M, Wang S, He H. Fushiming Capsule Attenuates Diabetic Rat Retina Damage via Antioxidation and Anti-Inflammation. Evid Based Complement Alternat Med. 2019;2019:5376439 pubmed publisher
Sun L, Zhang W, Li Z, Li M, Guo J, Wang H, et al. The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage. Sci Rep. 2019;9:11510 pubmed publisher
Zhang R, Qi F, Zhao F, Li G, Shao S, Zhang X, et al. Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer. Cell Death Dis. 2019;10:273 pubmed publisher
Yang D, Xiao C, Long F, Wu W, Huang M, Qu L, et al. Fra-1 plays a critical role in angiotensin II-induced vascular senescence. FASEB J. 2019;33:7603-7614 pubmed publisher
Zhao S, Liang M, Wang Y, Hu J, Zhong Y, Li J, et al. Chrysin Suppresses Vascular Endothelial Inflammation via Inhibiting the NF-κB Signaling Pathway. J Cardiovasc Pharmacol Ther. 2019;24:278-287 pubmed publisher
Jiang F, Wu G, Li W, Yang J, Yan J, Wang Y, et al. Preparation and protective effects of 1,8-cineole-loaded self-microemulsifying drug delivery system on lipopolysaccharide-induced endothelial injury in mice. Eur J Pharm Sci. 2019;127:14-23 pubmed publisher
Liu X, Du H, Chen D, Yuan H, Chen W, Jia W, et al. Cyclophilin D deficiency protects against the development of mitochondrial ROS and cellular inflammation in aorta. Biochem Biophys Res Commun. 2018;: pubmed publisher
Luo X, Yang D, Wu W, Long F, Xiao C, Qin M, et al. Critical role of histone demethylase Jumonji domain-containing protein 3 in the regulation of neointima formation following vascular injury. Cardiovasc Res. 2018;114:1894-1906 pubmed publisher
Shen D, Tian L, Shen T, Sun H, Liu P. Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice. Cell Physiol Biochem. 2018;47:2261-2277 pubmed publisher
Zhang H, Wang Y, Gao C, Gu Y, Huang J, Wang J, et al. Salvianolic acid A attenuates kidney injury and inflammation by inhibiting NF-κB and p38 MAPK signaling pathways in 5/6 nephrectomized rats. Acta Pharmacol Sin. 2018;39:1855-1864 pubmed publisher
Chen X, Wu Q, Jiang H, Wang J, Zhao Y, Xu Y, et al. SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells. Acta Biochim Biophys Sin (Shanghai). 2018;50:635-642 pubmed publisher
Yang D, Xiao C, Long F, Su Z, Jia W, Qin M, et al. HDAC4 regulates vascular inflammation via activation of autophagy. Cardiovasc Res. 2018;114:1016-1028 pubmed publisher
Crider A, Feng T, Pandya C, Davis T, Nair A, Ahmed A, et al. Complement component 3a receptor deficiency attenuates chronic stress-induced monocyte infiltration and depressive-like behavior. Brain Behav Immun. 2018;70:246-256 pubmed publisher
Teng Y, Feng C, Liu Y, Jin H, Gao Y, Li T. Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats. Exp Anim. 2018;67:313-320 pubmed publisher
Ma C, Zhang W, Yang X, Liu Y, Liu L, Feng K, et al. Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy. Br J Pharmacol. 2018;175:1486-1503 pubmed publisher
Zhang F, Lu S, He J, Jin H, Wang F, Wu L, et al. Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α. Theranostics. 2018;8:610-626 pubmed publisher
Sun H, Chen D, Wang P, Wan M, Zhang C, Zhang Z, et al. Salusin-? Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma. Oxid Med Cell Longev. 2017;2017:6905217 pubmed publisher
Liu Y, Lin H, Lai S, Huang C, Huang B, Chen P, et al. MiR-181b modulates EGFR-dependent VCAM-1 expression and monocyte adhesion in glioblastoma. Oncogene. 2017;36:5006-5022 pubmed publisher
Guo X, Sun M, Dai C, Zhang X, Yin Q, Ling J, et al. Macrophage-stimulated microRNA expression in mural cells promotes transplantation-induced neointima formation. Oncotarget. 2017;8:30100-30111 pubmed publisher
Liu S, Yuan Y, Zhou Y, Zhao M, Chen Y, Cheng J, et al. Phloretin attenuates hyperuricemia-induced endothelial dysfunction through co-inhibiting inflammation and GLUT9-mediated uric acid uptake. J Cell Mol Med. 2017;21:2553-2562 pubmed publisher
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J. Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells. Diabetes Res Clin Pract. 2017;124:30-40 pubmed publisher
Zhang Q, Waqas Y, Yang P, Sun X, Liu Y, Ahmed N, et al. Cytological study on the regulation of lymphocyte homing in the chicken spleen during LPS stimulation. Oncotarget. 2017;8:7405-7419 pubmed publisher
Wang D, Li S, Fu J, Zhang S, Bai L, Guo L. Resveratrol defends blood-brain barrier integrity in experimental autoimmune encephalomyelitis mice. J Neurophysiol. 2016;116:2173-2179 pubmed publisher
Li L, Bian T, Lyu J, Cui D, Lei L, Yan F. Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide. Int Immunopharmacol. 2016;38:204-13 pubmed publisher
Feng H, Pyykko I, Zou J. Involvement of Ubiquitin-Editing Protein A20 in Modulating Inflammation in Rat Cochlea Associated with Silver Nanoparticle-Induced CD68 Upregulation and TLR4 Activation. Nanoscale Res Lett. 2016;11:240 pubmed publisher
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu K, et al. Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs. Biomed Pharmacother. 2016;80:63-72 pubmed publisher
Liu Y, Yang G, Zhang J, Xing K, Dai L, Cheng L, et al. Anti-TNF-α monoclonal antibody reverses psoriasis through dual inhibition of inflammation and angiogenesis. Int Immunopharmacol. 2015;28:731-43 pubmed publisher
Lehrke M, Kahles F, Makowska A, Tilstam P, Diebold S, Marx J, et al. PDE4 inhibition reduces neointima formation and inhibits VCAM-1 expression and histone methylation in an Epac-dependent manner. J Mol Cell Cardiol. 2015;81:23-33 pubmed publisher
Wu S, Xu H, Peng J, Wang C, Jin Y, Liu K, et al. Potent anti-inflammatory effect of dioscin mediated by suppression of TNF-α-induced VCAM-1, ICAM-1and EL expression via the NF-κB pathway. Biochimie. 2015;110:62-72 pubmed publisher
Jin Y, Liu K, Peng J, Wang C, Kang L, Chang N, et al. Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway. Toxicol Lett. 2015;232:149-58 pubmed publisher
product information
CatalogNo :
11444-1-AP
AntigenName :
VCAM-1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
vascular cell adhesion molecule 1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CD106, INCAM 100, V CAM 1, VCAM 1, VCAM1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC017276
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;Neurology;Signal transduction;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.