This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
TLE3
catalog :
11372-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig ex8b
Parolia A, Cieslik M, Chu S, Xiao L, Ouchi T, Zhang Y, et al. Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer. Nature. 2019;: pubmed publisher
Li Q, Sun Y, Jarugumilli G, Liu S, Dang K, Cotton J, et al. Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. Cell Stem Cell. 2020;26:675-692.e8 pubmed publisher
Wang L, Xu M, Kao C, Tsai S, Tsai M. Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1. J Clin Invest. 2019;: pubmed publisher
Ren Y, Xu X, Mao C, Han K, Xu Y, Cao B, et al. RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination. Acta Pharmacol Sin. 2019;: pubmed publisher
Pearson S, Loft A, Rajbhandari P, Simcox J, Lee S, Tontonoz P, et al. Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism. Genes Dev. 2019;33:747-762 pubmed publisher
Ogawa M, Yaginuma T, Nakatomi C, Nakajima T, Tada Shigeyama Y, Addison W, et al. Transducin-like enhancer of split 3 regulates proliferation of melanoma cells via histone deacetylase activity. Oncotarget. 2019;10:404-414 pubmed publisher
Xing S, Shao P, Li F, Zhao X, Seo W, Wheat J, et al. Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity. J Exp Med. 2018;215:2211-2226 pubmed publisher
Kokabu S, Nakatomi C, Matsubara T, Ono Y, Addison W, Lowery J, et al. The transcriptional co-repressor TLE3 regulates myogenic differentiation by repressing the activity of the MyoD transcription factor. J Biol Chem. 2017;292:12885-12894 pubmed publisher
Ortega F, Serrano M, Rodriguez Cuenca S, Moreno Navarrete J, Gómez Serrano M, Sabater M, et al. Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPARγ gene expression. J Mol Med (Berl). 2015;93:83-92 pubmed publisher
product information
CatalogNo :
11372-1-AP
AntigenName :
TLE3
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, co-IP, CoIP, ch-IP, chIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ESG, ESG3, GRG3, HsT18976, KIAA1547, TLE3
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC015729
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Metabolism;Signal transduction;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:50 ; IP 1:300 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.