IRF3 | Proteintech Group 11312-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

IRF3

catalog :

11312-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 39

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4b	Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, et al. Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS Pathog. 2019;15:e1008002 pubmed publisher
immunocytochemistry; human; loading ...; fig 2d western blot; human; loading ...; fig 2b	Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, et al. NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1. J Immunol. 2019;: pubmed publisher
western blot; mouse; 1:2000; loading ...; fig 3a, 3c, 4a	Liu Z, Wu C, Pan Y, Liu H, Wang X, Yang Y, et al. NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages. Sci Adv. 2019;5:eaav0163 pubmed publisher
western blot; mouse; 1:3000; loading ...; fig s4a	Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed publisher
western blot; human; loading ...; fig 5A western blot; mouse; loading ...; fig 2A	Bakshi S, Taylor J, Strickson S, McCartney T, Cohen P. Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon ?. Biochem J. 2017;474:1163-1174 pubmed publisher
western blot; human; loading ...; fig 7c	Zhang X, Zheng Z, Liu X, Shu B, Mao P, Bai B, et al. Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway. J Neuroinflammation. 2016;13:209 pubmed publisher
	Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, et al. Silica particles disorganize the polarization of pulmonary macrophages in mice. Ecotoxicol Environ Saf. 2020;193:110364 pubmed publisher
	Xue M, Liang H, Ji X, Liu Y, Ge Y, Hou L, et al. Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology. Nutr Metab (Lond). 2019;16:87 pubmed publisher
	Hu S, Sun H, Yin L, Li J, Mei S, Xu F, et al. PKR-dependent cytosolic cGAS foci are necessary for intracellular DNA sensing. Sci Signal. 2019;12: pubmed publisher
	Wan W, Wang L, Chen X, Zhu S, Shang W, Xiao G, et al. A Subcellular Quantitative Proteomic Analysis of Herpes Simplex Virus Type 1-Infected HEK 293T Cells. Molecules. 2019;24: pubmed publisher
	Lou Y, Han M, Liu H, Niu Y, Liang Y, Guo J, et al. Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection. Cell Mol Immunol. 2019;: pubmed publisher
	Zhu W, Li J, Zhang R, Cai Y, Wang C, Qi S, et al. TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity. EMBO J. 2019;:e102075 pubmed publisher
	Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed publisher
	Sanjo H, Nakayama J, Yoshizawa T, Fehling H, Akira S, Taki S. Cutting Edge: TAK1 Safeguards Macrophages against Proinflammatory Cell Death. J Immunol. 2019;203:783-788 pubmed publisher
	Chavez Valdez R, Mottahedin A, Stridh L, Yellowhair T, Jantzie L, Northington F, et al. Evidence for Sexual Dimorphism in the Response to TLR3 Activation in the Developing Neonatal Mouse Brain: A Pilot Study. Front Physiol. 2019;10:306 pubmed publisher
	Guan X, Zhang M, Fu M, Luo S, Hu Q. Herpes Simplex Virus Type 2 Immediate Early Protein ICP27 Inhibits IFN-β Production in Mucosal Epithelial Cells by Antagonizing IRF3 Activation. Front Immunol. 2019;10:290 pubmed publisher
	Su Z, Dziedzic S, Hu D, Barrett V, Broekema N, Li W, et al. ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner. Cell Death Differ. 2019;26:1077-1088 pubmed publisher
	Yang Q, Tang J, Pei R, Gao X, Guo J, Xu C, et al. Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3. J Mol Cell Biol. 2019;11:158-169 pubmed publisher
	Wang X, Wu J, Wu Y, Chen H, Zhang S, Li J, et al. Inhibition of cGAS-STING-TBK1 signaling pathway by DP96R of ASFV China 2018/1. Biochem Biophys Res Commun. 2018;506:437-443 pubmed publisher
	Gao X, Chen D, Hu X, Zhou Y, Wang Y, Wu C, et al. PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria. J Innate Immun. 2018;10:315-327 pubmed publisher
	Cai J, Chen H, Peng S, Meng J, Wang Y, Zhou Y, et al. USP7-TRIM27 axis negatively modulates antiviral type I IFN signaling. FASEB J. 2018;32:5238-5249 pubmed publisher
	Zhou P, Ding X, Wan X, Liu L, Yuan X, Zhang W, et al. MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation. Nat Commun. 2018;9:1243 pubmed publisher
	Xie J, Li Y, Shen X, Goh G, Zhu Y, Cui J, et al. Dampened STING-Dependent Interferon Activation in Bats. Cell Host Microbe. 2018;23:297-301.e4 pubmed publisher
	Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, et al. PTEN-L promotes type I interferon responses and antiviral immunity. Cell Mol Immunol. 2018;15:48-57 pubmed publisher
	Lian S, Guo J, Wang L, Li W, Wang J, Ji H, et al. Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats. Oncotarget. 2017;8:115304-115314 pubmed publisher
	Yi C, Zhao Z, Wang S, Sun X, Zhang D, Sun X, et al. Influenza A Virus PA Antagonizes Interferon-? by Interacting with Interferon Regulatory Factor 3. Front Immunol. 2017;8:1051 pubmed publisher
	Zhao M, Wan B, Li H, He J, Chen X, Wang L, et al. Porcine 2', 5'-oligoadenylate synthetase 2 inhibits porcine reproductive and respiratory syndrome virus replication in vitro. Microb Pathog. 2017;111:14-21 pubmed publisher
	Zhang H, Ye H, Liu S, Deng C, Li X, Shi P, et al. West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5. J Virol. 2017;91: pubmed publisher
	Jiang Z, Song F, Li Y, Xue D, Deng G, Li M, et al. Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells. Mediators Inflamm. 2017;2017:9891673 pubmed publisher
	Nie Y, Ran Y, Zhang H, Huang Z, Pan Z, Wang S, et al. GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome. PLoS Pathog. 2017;13:e1006328 pubmed publisher
	Song S, Peng P, Tang Z, Zhao J, Wu W, Li H, et al. Decreased expression of STING predicts poor prognosis in patients with gastric cancer. Sci Rep. 2017;7:39858 pubmed publisher
	Lang X, Tang T, Jin T, Ding C, Zhou R, Jiang W. TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity. J Exp Med. 2017;214:459-473 pubmed publisher
	Liu C, Yue R, Yang Y, Cui Y, Yang L, Zhao D, et al. AIM2 inhibits autophagy and IFN-? production during M. bovis infection. Oncotarget. 2016;7:46972-46987 pubmed publisher
	Zeng L, Gao Y, Ge X, Zhang Q, Peng C, Yang X, et al. Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1 Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. J Virol. 2016;90:6573-6582 pubmed publisher
	Li S, Zhu M, Pan R, Fang T, Cao Y, Chen S, et al. The tumor suppressor PTEN has a critical role in antiviral innate immunity. Nat Immunol. 2016;17:241-9 pubmed publisher
	Li L, Qin J, Guo S, Zhang P, Gong J, Zhang X, et al. Attenuation of cerebral ischemic injury in interferon regulatory factor 3-deficient rat. J Neurochem. 2016;136:871-883 pubmed publisher
	Zhu M, Fang T, Li S, Meng K, Guo D. Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3. J Immunol. 2015;195:289-97 pubmed publisher
	Li M, Guo S, Zhang P, Gong J, Zheng A, Zhang Y, et al. Vinexin-Î² deficiency protects against cerebral ischaemia/reperfusion injury by inhibiting neuronal apoptosis. J Neurochem. 2015;134:211-21 pubmed publisher
	Zhang M, Liu Y, Wang P, Guan X, He S, Luo S, et al. HSV-2 immediate-early protein US1 inhibits IFN-Î² production by suppressing association of IRF-3 with IFN-Î² promoter. J Immunol. 2015;194:3102-15 pubmed publisher

product information

CatalogNo :

11312-1-AP

AntigenName :

IRF3

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

interferon regulatory factor 3

Immunogen :

Recombinant Protein

Species :

human, mouse, pig, rat, sheep, swine

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, IF, FC, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

interferon regulatory factor 3, IRF 3, IRF3

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC009395

Category :

Binding Proteins;Cytoskeleton/Scaffold Proteins;Immunology;Metabolism;Oncogene(s) and Tumor Suppressor(s);Signal transduction;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

FC 1:0 ; IF 1:25 ; IHC 1:50 ; IP 1:1000 ; WB 1:5000 ;