This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CD31
catalog :
11265-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 62
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:100; fig 3
Liu L, Tong Q, Liu S, Cui J, Zhang Q, Sun W, et al. ZEB1 Upregulates VEGF Expression and Stimulates Angiogenesis in Breast Cancer. PLoS ONE. 2016;11:e0148774 pubmed publisher
Xie M, Yu T, Jing X, Ma L, Fan Y, Yang F, et al. Exosomal circSHKBP1 promotes gastric cancer progression via regulating the miR-582-3p/HUR/VEGF axis and suppressing HSP90 degradation. Mol Cancer. 2020;19:112 pubmed publisher
Zhao Y, Wang L, Peng A, Liu X, Wang Y, Huang S, et al. The neuroprotective and neurorestorative effects of growth differentiation factor 11 in cerebral ischemic injury. Brain Res. 2020;1737:146802 pubmed publisher
Zong J, Jiang J, Shi P, Liu J, Wang W, Li B, et al. Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-β/Smad3 signaling and promoting angiogenesis. Am J Transl Res. 2020;12:478-492 pubmed
Zeng Z, Du H, Xiong L, Zeng X, Zhang P, Cai J, et al. BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest. Life Sci. 2020;244:117342 pubmed publisher
Zhai L, Liu Y, Zhao W, Chen Q, Guo T, Wei W, et al. Aerobic and resistance training enhances endothelial progenitor cell function via upregulation of caveolin-1 in mice with type 2 diabetes. Stem Cell Res Ther. 2020;11:10 pubmed publisher
Wang M, Yan J, Cao X, Hua P, Li Z. Hydrogen sulfide modulates epithelial-mesenchymal transition and angiogenesis in non-small cell lung cancer via HIF-1α activation. Biochem Pharmacol. 2020;172:113775 pubmed publisher
Shao J, Li Y, Zhou C, Geng M, Zhang G, Zhang N, et al. TIPE1 accelerates atherogenesis by inducing endothelial dysfunction in response to oxidative stress. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165578 pubmed publisher
Xia B, Wang J. Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression. Drug Des Devel Ther. 2019;13:3837-3844 pubmed publisher
Li Z, Chen B, Dong W, Kong M, Fan Z, Yu L, et al. MKL1 promotes endothelial-to-mesenchymal transition and liver fibrosis by activating TWIST1 transcription. Cell Death Dis. 2019;10:899 pubmed publisher
Li Z, Chen B, Dong W, Kong M, Shao Y, Fan Z, et al. The Chromatin Remodeler Brg1 Integrates ROS Production and Endothelial-Mesenchymal Transition to Promote Liver Fibrosis in Mice. Front Cell Dev Biol. 2019;7:245 pubmed publisher
Yu L, Fu J, Yu N, Wu Y, Han N. Long non-coding RNA MALAT1 participates in the pathological angiogenesis of diabetic retinopathy in oxygen-induced retinopathy mouse model by sponging miR-203a-3p. Can J Physiol Pharmacol. 2019;: pubmed publisher
Zhu Y, Yu F, Tan Y, Hong Y, Meng T, Liu Y, et al. Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells. Theranostics. 2019;9:6764-6779 pubmed publisher
Zhang M, Weng H, Zheng J. NAD+ repletion inhibits the endothelial-to-mesenchymal transition induced by TGF-β in endothelial cells through improving mitochondrial unfolded protein response. Int J Biochem Cell Biol. 2019;117:105635 pubmed publisher
Zhang D, Yang Y, Liang C, Liu J, Wang H, Liu S, et al. poFUT1 promotes uterine angiogenesis and vascular remodeling via enhancing the O-fucosylation on uPA. Cell Death Dis. 2019;10:775 pubmed publisher
Gao X, Zhang Y, Zhang R, Zhao Z, Zhang H, Wu J, et al. Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis. Exp Ther Med. 2019;18:3062-3070 pubmed publisher
Han Y, Liu C, Zhang D, Men H, Huo L, Geng Q, et al. Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle. Int J Oncol. 2019;: pubmed publisher
Fang L, He Y, Liu Y, Ding H, Tong Y, Hu L, et al. Adjustment of Microvessel Area by Stromal Area to Improve Survival Prediction in Non-Small Cell Lung Cancer. J Cancer. 2019;10:3397-3406 pubmed publisher
Hou P, Chen F, Yong H, Lin T, Li J, Pan Y, et al. PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α. J Exp Clin Cancer Res. 2019;38:301 pubmed publisher
Hou P, Li H, Yong H, Chen F, Chu S, Zheng J, et al. PinX1 represses renal cancer angiogenesis via the mir-125a-3p/VEGF signaling pathway. Angiogenesis. 2019;: pubmed publisher
Nagai Okatani C, Nishigori M, Sato T, Minamino N, Kaji H, Kuno A. Wisteria floribunda agglutinin staining for the quantitative assessment of cardiac fibrogenic activity in a mouse model of dilated cardiomyopathy. Lab Invest. 2019;: pubmed publisher
Cheng F, Zhang P, Xiao Q, Li Y, Dong M, Wang H, et al. The Prognostic and Therapeutic Potential of LRIG3 and Soluble LRIG3 in Glioblastoma. Front Oncol. 2019;9:447 pubmed publisher
Yao Y, Li Y, Song Q, Hu C, Xie W, Xu C, et al. Angiogenic Factor AGGF1-Primed Endothelial Progenitor Cells Repair Vascular Defect in Diabetic Mice. Diabetes. 2019;: pubmed publisher
Wang H, Wang S, Zheng M, Dai L, Wang K, Gao X, et al. Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial-mesenchymal transition in salivary adenoid cystic carcinoma. Cell Prolif. 2019;52:e12600 pubmed publisher
Cvetanova B, Shen Y, Shyur L. Cumingianoside A, a Phyto-Triterpenoid Saponin Inhibits Acquired BRAF Inhibitor Resistant Melanoma Growth via Programmed Cell Death. Front Pharmacol. 2019;10:30 pubmed publisher
Zhu X, Wang Y, Jiang Q, Jiang H, Lu J, Wang Y, et al. All-trans retinoic acid protects mesenchymal stem cells from immune thrombocytopenia by regulating the complement-IL-1β loop. Haematologica. 2019;: pubmed publisher
Qu S, Wu J, Bao Q, Yao B, Duan R, Chen X, et al. Osterix promotes the migration and angiogenesis of breast cancer by upregulation of S100A4 expression. J Cell Mol Med. 2019;23:1116-1127 pubmed publisher
Wang B, Wang X, Hou D, Huang Q, Zhan W, Chen C, et al. Exosomes derived from acute myeloid leukemia cells promote chemoresistance by enhancing glycolysis-mediated vascular remodeling. J Cell Physiol. 2019;234:10602-10614 pubmed publisher
Yuan R, Shi W, Xin Q, Yang B, Hoi M, Lee S, et al. Tetramethylpyrazine and Paeoniflorin Inhibit Oxidized LDL-Induced Angiogenesis in Human Umbilical Vein Endothelial Cells via VEGF and Notch Pathways. Evid Based Complement Alternat Med. 2018;2018:3082507 pubmed publisher
Zhang Q, Yi D, Xue B, Wen W, Lu Y, Abdelmaksou A, et al. CD90 determined two subpopulations of glioma-associated mesenchymal stem cells with different roles in tumour progression. Cell Death Dis. 2018;9:1101 pubmed publisher
Li Z, Liu X, Tian F, Li J, Wang Q, Gu C. MKP2 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells through a JNK-dependent pathway. Clin Sci (Lond). 2018;132:2339-2355 pubmed publisher
Peng Y, Wang Y, Tang N, Sun D, Lan Y, Yu Z, et al. Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway. J Exp Clin Cancer Res. 2018;37:248 pubmed publisher
Liu H, Tang L, Li X, Li H. Triptolide inhibits vascular endothelial growth factor-mediated angiogenesis in human breast cancer cells. Exp Ther Med. 2018;16:830-836 pubmed publisher
Hong S, Chen S, Wang X, Sun D, Yan Z, Tai J, et al. ATAD2 silencing decreases VEGFA secretion through targeting has-miR-520a to inhibit angiogenesis in colorectal cancer. Biochem Cell Biol. 2018;96:761-768 pubmed publisher
Sun X, Huang S, Zhang X, Wang X. CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia. Oncotarget. 2018;9:27574-27584 pubmed publisher
He W, Ye S, Zeng C, Xue S, Hu X, Zhang X, et al. Hypothermic oxygenated perfusion (HOPE) attenuates ischemia/reperfusion injury in the liver through inhibition of the TXNIP/NLRP3 inflammasome pathway in a rat model of donation after cardiac death. FASEB J. 2018;:fj201800028RR pubmed publisher
Mei L, Rao J, Liu Y, Li M, Zhang Z, He Q. Effective treatment of the primary tumor and lymph node metastasis by polymeric micelles with variable particle sizes. J Control Release. 2018;292:67-77 pubmed publisher
Zhu Y, Wen L, Shao S, Tan Y, Meng T, Yang X, et al. Inhibition of tumor-promoting stroma to enforce subsequently targeting AT1R on tumor cells by pathological inspired micelles. Biomaterials. 2018;161:33-46 pubmed publisher
Zhang F, Lu S, He J, Jin H, Wang F, Wu L, et al. Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α. Theranostics. 2018;8:610-626 pubmed publisher
Xie H, Wang F, Chen X, Ying H. miR?126 is essential for endothelial phenotype expression during endothelial differentiation in adipose?derived stem cells. Mol Med Rep. 2018;17:442-446 pubmed publisher
Fu S, Chen H, Lin X, Yang L, Ge Z. Collagen triple helix repeat containing 1 promotes tumor angiogenesis in gastrointestinal stromal tumors. Oncol Lett. 2017;14:7499-7505 pubmed publisher
Chen X, Han Y, Zhang B, Liu Y, Wang S, Liao T, et al. Caffeic acid phenethyl ester promotes haematopoietic stem/progenitor cell homing and engraftment. Stem Cell Res Ther. 2017;8:255 pubmed publisher
Hao Y, Zheng C, Wang L, Zhang J, Niu X, Song Q, et al. Tumor acidity-activatable manganese phosphate nanoplatform for amplification of photodynamic cancer therapy and magnetic resonance imaging. Acta Biomater. 2017;62:293-305 pubmed publisher
Wang J, Liu K, Wang X, Sun D. Juglone reduces growth and migration of U251 glioblastoma cells and disrupts angiogenesis. Oncol Rep. 2017;38:1959-1966 pubmed publisher
Alloza I, Goikuria H, Idro J, Triviño J, Fernández Velasco J, Elizagaray E, et al. RNAseq based transcriptomics study of SMCs from carotid atherosclerotic plaque: BMP2 and IDs proteins are crucial regulators of plaque stability. Sci Rep. 2017;7:3470 pubmed publisher
Gao W, Li S, Liu Z, Sun Y, Cao W, Tong L, et al. Targeting and destroying tumor vasculature with a near-infrared laser-activated "nanobomb" for efficient tumor ablation. Biomaterials. 2017;139:1-11 pubmed publisher
Tan K, Zheng K, Li D, Lu H, Wang S, Sun X. Impact of adipose tissue or umbilical cord derived mesenchymal stem cells on the immunogenicity of human cord blood derived endothelial progenitor cells. PLoS ONE. 2017;12:e0178624 pubmed publisher
Zhu J, Wang H, Zhang X, Xie Y. Regulation of angiogenic behaviors by oxytocin receptor through Gli1-indcued transcription of HIF-1α in human umbilical vein endothelial cells. Biomed Pharmacother. 2017;90:928-934 pubmed publisher
Fang L, He Y, Tong Y, Hu L, Xin W, Liu Y, et al. Flattened microvessel independently predicts poor prognosis of patients with non-small cell lung cancer. Oncotarget. 2017;8:30092-30099 pubmed publisher
Yu C, Suriguga -, Gong M, Liu W, Cui N, Wang Y, et al. High glucose induced endothelial to mesenchymal transition in human umbilical vein endothelial cell. Exp Mol Pathol. 2017;102:377-383 pubmed publisher
Zimmerer R, Ludwig N, Kampmann A, Bittermann G, Spalthoff S, Jungheim M, et al. CD24+ tumor-initiating cells from oral squamous cell carcinoma induce initial angiogenesis in vivo. Microvasc Res. 2017;112:101-108 pubmed publisher
Zhang F, Hao M, Jin H, Yao Z, Lian N, Wu L, et al. Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis. Br J Pharmacol. 2017;174:409-423 pubmed publisher
Guo X, Wei S, Lu M, Shao Z, Lu J, Xia L, et al. Dose-dependent Effects of Strontium Ranelate on Ovariectomy Rat Bone Marrow Mesenchymal Stem Cells and Human Umbilical Vein Endothelial Cells. Int J Biol Sci. 2016;12:1511-1522 pubmed
Li G, Zheng J, Xu B, Ling J, Qiu W, Wang Y. Simvastatin inhibits tumor angiogenesis in HER2-overexpressing human colorectal cancer. Biomed Pharmacother. 2017;85:418-424 pubmed publisher
Mendoza A, Woodruff T, Wignall S, O Halloran T. Zinc availability during germline development impacts embryo viability in Caenorhabditis elegans. Comp Biochem Physiol C Toxicol Pharmacol. 2017;191:194-202 pubmed publisher
Jia Y, Wang Z, Zang A, Jiao S, Chen S, Fu Y. Tetramethylpyrazine inhibits tumor growth of lung cancer through disrupting angiogenesis via BMP/Smad/Id-1 signaling. Int J Oncol. 2016;48:2079-86 pubmed publisher
Zhang Y, Yang J, Wang T, Wang S, Liu J, Yin C, et al. Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction. J Sex Med. 2016;13:350-60 pubmed publisher
Deng Y, Guo Y, Liu P, Zeng R, Ning Y, Pei G, et al. Blocking protein phosphatase 2A signaling prevents endothelial-to-mesenchymal transition and renal fibrosis: a peptide-based drug therapy. Sci Rep. 2016;6:19821 pubmed publisher
Dinsmore C, Reiter J. Endothelial primary cilia inhibit atherosclerosis. EMBO Rep. 2016;17:156-66 pubmed publisher
Vishnubalaji R, Atteya M, Al Nbaheen M, Oreffo R, Aldahmash A, Alajez N. Angiogenic Potential of Human Neonatal Foreskin Stromal Cells in the Chick Embryo Chorioallantoic Membrane Model. Stem Cells Int. 2015;2015:257019 pubmed publisher
Wang H, Wang S, Song W, Pan Y, Yu H, Si T, et al. Expression of prostate-specific membrane antigen in lung cancer cells and tumor neovasculature endothelial cells and its clinical significance. PLoS ONE. 2015;10:e0125924 pubmed publisher
Chen K, Yu G, Gumireddy K, Li A, Yao W, Gao L, et al. ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer. Oncotarget. 2015;6:6959-76 pubmed
product information
CatalogNo :
11265-1-AP
AntigenName :
CD31
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
platelet/endothelial cell adhesion molecule
Immunogen :
Recombinant Protein
Species :
human, monkey, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CD31, EndoCAM, GPIIA, PECA1, PECAM 1, PECAM1, VEC marker
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC022512
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;IVD;Membrane Proteins;Signal transduction;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:800 ; IP 1:300 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.