This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Cathepsin K
catalog :
11239-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; fig 5
Haque M, Song J, Fino K, Sandhu P, Song X, Lei F, et al. Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity. Sci Rep. 2016;6:20588 pubmed publisher
Qian Z, Zhong Z, Ni S, Li D, Zhang F, Zhou Y, et al. Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis. J Cell Mol Med. 2020;: pubmed publisher
Zhu M, Liu H, Sun K, Liu J, Mou Y, Qi D, et al. Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss. Biomed Pharmacother. 2020;123:109769 pubmed publisher
Zhong Z, Qian Z, Zhang X, Chen F, Ni S, Kang Z, et al. Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis. Front Pharmacol. 2019;10:1530 pubmed publisher
Fujii Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Kishida T, et al. Treadmill Running in Established Phase Arthritis Inhibits Joint Destruction in Rat Rheumatoid Arthritis Models. Int J Mol Sci. 2019;20: pubmed publisher
Yang S, Liu H, Zhu L, Li X, Liu D, Song X, et al. Ankle loading ameliorates bone loss from breast cancer-associated bone metastasis. FASEB J. 2019;:fj201900306RR pubmed publisher
Dong L, Wu J, Chen K, Xie J, Wang Y, Li D, et al. Mannan-Binding Lectin Attenuates Inflammatory Arthritis Through the Suppression of Osteoclastogenesis. Front Immunol. 2019;10:1239 pubmed publisher
Pi Y, Liang H, Yu Q, Yin Y, Xu H, Lei Y, et al. Low‑frequency pulsed electromagnetic field inhibits RANKL‑induced osteoclastic differentiation in RAW264.7 cells by scavenging reactive oxygen species. Mol Med Rep. 2019;19:4129-4136 pubmed publisher
Parks A, Nahata J, Edouard N, Temenoff J, Platt M. Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis. Sci Rep. 2019;9:5399 pubmed publisher
Lou Z, Peng Z, Wang B, Li X, Li X, Zhang X. miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway. J Bone Miner Metab. 2019;: pubmed publisher
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X. ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth. Theranostics. 2019;9:1387-1400 pubmed publisher
Liu H, Dong Y, Gao Y, Zhao L, Cai C, Qi D, et al. Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss. J Cell Physiol. 2019;234:11009-11022 pubmed publisher
Cai C, Liu C, Zhao L, Liu H, Li W, Guan H, et al. Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo. Front Pharmacol. 2018;9:1286 pubmed publisher
Sun J, Chang T, Li M, Sun L, Yan X, Yang Z, et al. SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization. Angiogenesis. 2018;21:635-652 pubmed publisher
Xu R, Shi G, Xu L, Gu Q, Fu Y, Zhang P, et al. Simvastatin improves oral implant osseointegration via enhanced autophagy and osteogenesis of BMSCs and inhibited osteoclast activity. J Tissue Eng Regen Med. 2018;12:1209-1219 pubmed publisher
Zhao L, Guan H, Song C, Wang Y, Liu C, Cai C, et al. YAP1 is essential for osteoclastogenesis through a TEADs-dependent mechanism. Bone. 2018;110:177-186 pubmed publisher
Li J, Yang S, Li X, Liu D, Wang Z, Guo J, et al. Role of endoplasmic reticulum stress in disuse osteoporosis. Bone. 2017;97:2-14 pubmed publisher
Zhang J, Xu H, Han Z, Chen P, Yu Q, Lei Y, et al. Pulsed electromagnetic field inhibits RANKL-dependent osteoclastic differentiation in RAW264.7 cells through the Ca2+-calcineurin-NFATc1 signaling pathway. Biochem Biophys Res Commun. 2017;482:289-295 pubmed publisher
Li X, Yang J, Liu D, Li J, Niu K, Feng S, et al. Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis. Sci Rep. 2016;6:24668 pubmed publisher
Sun T, Jiang D, Zhang L, Su Q, Mao W, Jiang C. Expression profile of cathepsins indicates the potential of cathepsins B and D as prognostic factors in breast cancer patients. Oncol Lett. 2016;11:575-583 pubmed
Kozawa E, Cheng X, Urakawa H, Arai E, Yamada Y, Kitamura S, et al. Increased expression and activation of cathepsin K in human osteoarthritic cartilage and synovial tissues. J Orthop Res. 2016;34:127-34 pubmed publisher
Xue Y, Wang L, Xia D, Li Q, Gao S, Dong M, et al. Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations. J Dent Res. 2015;94:674-81 pubmed publisher
Sumida K, Ubara Y, Hoshino J, Hayami N, Suwabe T, Hiramatsu R, et al. Bone histomorphometry in a long-term hemodialysis patient with hypoparathyroidism and sarcoidosis. Osteoporos Int. 2015;26:1435-41 pubmed publisher
product information
CatalogNo :
11239-1-AP
AntigenName :
Cathepsin K
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
cathepsin K
Immunogen :
Recombinant Protein
Species :
human, mouse, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Cathepsin K, Cathepsin O, Cathepsin O2, Cathepsin X, catK, CTS02, CTSK, CTSO, CTSO1, CTSO2, PKND, PYCD
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC016058
Category :
Binding Proteins;Disease Related;Metabolism;Plasma/Serum;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.