This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
UCP2
catalog :
11081-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 16
Reference
Zhou H, Yuan D, Gao W, Tian J, Sun H, Yu S, et al. Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia. IUBMB Life. 2020;72:1659-1679 pubmed publisher
Lu B, Zhong J, Pan J, Yuan X, Ren M, Jiang L, et al. Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice. J Transl Med. 2019;17:422 pubmed publisher
Ikeda K, Onimaru H, Matsuura T, Kawakami K. Different impacts on brain function depending on the mode of delivery. Brain Res. 2019;: pubmed publisher
Huang J, Peng W, Zheng Y, Hao H, Li S, Yao Y, et al. Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes. Oxid Med Cell Longev. 2019;2019:2758262 pubmed publisher
Watamoto Y, Futawaka K, Hayashi M, Matsushita M, Mitsutani M, Murakami K, et al. Insulin-like growth factor-1 directly mediates expression of mitochondrial uncoupling protein 3 via forkhead box O4. Growth Horm IGF Res. 2019;46-47:24-35 pubmed publisher
Wang J, Yu R, Han Q, Huang H, Wang Y, Li H, et al. G-1 exhibit antidepressant effect, increase of hippocampal ERs expression and improve hippocampal redox status in aged female rats. Behav Brain Res. 2019;359:845-852 pubmed publisher
Zhong H, Liu M, Ji Y, Ma M, Chen K, Liang T, et al. Genipin Reverses HFD-Induced Liver Damage and Inhibits UCP2-Mediated Pyroptosis in Mice. Cell Physiol Biochem. 2018;49:1885-1897 pubmed publisher
Rodríguez Hidalgo M, Luna Sánchez M, Hidalgo Gutiérrez A, Barriocanal Casado E, Mascaraque C, Acuna Castroviejo D, et al. Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. Sci Rep. 2018;8:14013 pubmed publisher
Chen G, Zhang J, Chen Y, Zhang J, Wang T, Zeng Q. Insulin alleviates mitochondrial oxidative stress involving upregulation of superoxide dismutase 2 and uncoupling protein 2 in septic acute kidney injury. Exp Ther Med. 2018;15:3967-3975 pubmed publisher
Wang X, Sun B, Jiang Q, Wu R, Cai M, Yao Y, et al. mRNA m6A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes. Int J Obes (Lond). 2018;42:1912-1924 pubmed publisher
Chen K, Xu Z, Liu Y, Wang Z, Li Y, Xu X, et al. Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury. Sci Transl Med. 2017;9: pubmed publisher
He K, Li X, Xiao Y, Yong Y, Zhang Z, Li S, et al. Hypolipidemic effects of Myrica rubra extracts and main compounds in C57BL/6j mice. Food Funct. 2016;7:3505-15 pubmed publisher
Chen G, Yan J, Wang X, Zheng M, Jiang J, Zhou X, et al. Mechanism of uncoupling protein 2?mediated myocardial injury in hypothermic preserved rat hearts. Mol Med Rep. 2016;14:1857-64 pubmed publisher
He K, Hu Y, Ma H, Zou Z, Xiao Y, Yang Y, et al. Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways. Biochim Biophys Acta. 2016;1862:1696-709 pubmed publisher
Yu S, Du C, Chen W, Lei Q, Li N, Qi S, et al. Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression. Sci Rep. 2015;5:17935 pubmed publisher
Xie X, Zhang J, Chen D, Pan H, Wu Z, Ge D, et al. Effects of ghrelin on postresuscitation brain injury in a rat model of cardiac arrest. Shock. 2015;43:490-6 pubmed publisher
product information
CatalogNo :
11081-1-AP
AntigenName :
UCP2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
uncoupling protein 2 (mitochondrial, proton carrier)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
BMIQ4, SLC25A8, UCP 2, UCP2, UCPH
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC011737
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.