This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
ACOX1
catalog :
10957-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 24
Reference
Wang J, Zhang Y, Zhuo Q, Tseng Y, Wang J, Ma Y, et al. TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter. Nutr Metab (Lond). 2020;17:46 pubmed publisher
He A, Chen X, Tan M, Chen Y, Lu D, Zhang X, et al. Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation. Mol Cell. 2020;79:30-42.e4 pubmed publisher
Miyamoto T, Hosoba K, Itabashi T, Iwane A, Akutsu S, Ochiai H, et al. Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome. EMBO J. 2020;39:e103499 pubmed publisher
Xu L, Xia H, Ni D, Hu Y, Liu J, Qin Y, et al. High-Dose Dexamethasone Manipulates the Tumor Microenvironment and Internal Metabolic Pathways in Anti-Tumor Progression. Int J Mol Sci. 2020;21: pubmed publisher
Iizuka Y, Chiba K, Kim H, Hirako S, Wada M, Matsumoto A. Impact of discontinuation of fish oil after pioglitazone-fish oil combination therapy in diabetic KK mice. J Nutr Biochem. 2020;76:108265 pubmed publisher
Zhang Y, Wang S, Zhao T, Yang L, Guo S, Shi Y, et al. Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells. Ecotoxicol Environ Saf. 2019;184:109611 pubmed publisher
Zhang Y, Zhang Z, Zhou L, Zhu J, Zhang X, Qi W, et al. Di (2-ethylhexyl) phthalate Disorders Lipid Metabolism via TYK2/STAT1 and Autophagy in Rats. Biomed Environ Sci. 2019;32:406-418 pubmed publisher
Luo Y, Xie C, Brocker C, Fan J, Wu X, Feng L, et al. Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6. Gastroenterology. 2019;: pubmed publisher
Luo M, Huang S, Zhang J, Zhang L, Mehmood K, Jiang J, et al. Effect of selenium nanoparticles against abnormal fatty acid metabolism induced by hexavalent chromium in chicken's liver. Environ Sci Pollut Res Int. 2019;: pubmed publisher
Wang J, Zhang Y, Tseng Y, Zhang J. miR-222 targets ACOX1, promotes triglyceride accumulation in hepatocytes. Hepatobiliary Pancreat Dis Int. 2019;: pubmed publisher
Yao L, Cao B, Cheng Q, Cai W, Ye C, Liang J, et al. Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice. Am J Physiol Gastrointest Liver Physiol. 2019;316:G527-G538 pubmed publisher
Kumar S, Rani R, Karns R, Gandhi C. Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression. FASEB J. 2019;33:3825-3840 pubmed publisher
Park H, He A, Tan M, Johnson J, Dean J, Pietka T, et al. Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest. 2019;129:694-711 pubmed publisher
Lyu Z, Mao Z, Li Q, Xia Y, Liu Y, He Q, et al. PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules. EBioMedicine. 2018;38:178-190 pubmed publisher
Eun S, Lee J, Nam I, Liu Z, So H, Choe S, et al. PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation. Exp Mol Med. 2018;50:4 pubmed publisher
Chen X, Tian M, Sun R, Zhang M, Zhou L, Jin L, et al. SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer. EMBO Rep. 2018;19: pubmed publisher
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z. Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury. Sci Rep. 2018;8:408 pubmed publisher
Lai Y, Liu H, Chiang W, Chen T, Chu L, Yu J, et al. MiR-31-5p-ACOX1 Axis Enhances Tumorigenic Fitness in Oral Squamous Cell Carcinoma Via the Promigratory Prostaglandin E2. Theranostics. 2018;8:486-504 pubmed publisher
Ferdinandusse S, Denis S, van Roermund C, Preece M, Koster J, Ebberink M, et al. A novel case of ACOX2 deficiency leads to recognition of a third human peroxisomal acyl-CoA oxidase. Biochim Biophys Acta Mol Basis Dis. 2018;1864:952-958 pubmed publisher
Xiao Y, Wang J, Yan W, Zhou K, Cao Y, Cai W. p38? MAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure. Cell Death Dis. 2017;8:e3110 pubmed publisher
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z. Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice. Sci Rep. 2017;7:8976 pubmed publisher
Sun Q, Zhang W, Zhong W, Sun X, Zhou Z. Dietary Fisetin Supplementation Protects Against Alcohol-Induced Liver Injury in Mice. Alcohol Clin Exp Res. 2016;40:2076-2084 pubmed publisher
Niewiadomski J, Zhou J, Roman H, Liu X, Hirschberger L, Locasale J, et al. Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice. Ann N Y Acad Sci. 2016;1363:99-115 pubmed publisher
Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed publisher
product information
CatalogNo :
10957-1-AP
AntigenName :
ACOX1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
acyl-Coenzyme A oxidase 1, palmitoyl
Immunogen :
Recombinant Protein
Species :
chicken, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ACOX, ACOX1, AOX, PALMCOX, Palmitoyl CoA oxidase, SCOX
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC010425
Category :
Cytoskeleton/Scaffold Proteins;Development;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:200 ; WB 1:4000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.